Kansas City Chiefs vs Los Angeles Chargers Odds

The Chiefs will play the Chargers on Friday, September 5th, 2025. The matchup takes place at Corinthians Arena. Watch this exciting Week 1 matchup at 8:20 pm EDT. Check local listings for coverage on YouTube.

Learn more about NFL betting with our handy tutorial and guide. Know when to bet the spread, moneyline, totals or props.


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Table of Contents

Key Matchup Stats

It's early in the 2025-26 NFL regular season for the Kansas City Chiefs and Los Angeles Chargers. Let's review some stats from the 2024 regular season to get an idea of how these teams will fare.

  • SportsBetting3.com Power Rankings - The Kansas City Chiefs had a 95.33 power ranking in the 2024 regular season. The power ranking for the Los Angeles Chargers in the 2024 regular season was 96.00.
  • Away Kansas City Chiefs - At the end of the 2024 regular season, the Kansas City Chiefs had a 7-2-0 record as an away team, ranking them 2nd in the regular season for away team wins.
  • Home Los Angeles Chargers - The Los Angeles Chargers finished the 2024 regular season with a 5-3-0 record as a home team. They ranked 4th for home team wins in the regular season standings.
  • Points Scored - The Kansas City Chiefs wound up 14th (385) in the regular season, with the Los Angeles Chargers ranked 11th (402) for points scored in the 2024 regular season.
  • Points Against - The Kansas City Chiefs finished 26th (326) in the regular season for points against. The Los Angeles Chargers wound up 29th (301) in the 2024 regular season for points against.
  • Team Records - The Kansas City Chiefs had a 15-2-0 regular season record, with the Los Angeles Chargers notching a 11-6-0 regular season standing last year.

Captain Shady Lines

A broken compass is right at least twice a day.

Captain Shady Lines
Captain Shady Lines

Arrr, mateys! The Kansas City Chiefs sail to Los Angeles Chargers' home turf. The Chiefs, with their mighty 15-2-0 record, be ready for battle.

Ye Chargers, with an 11-6-0 standing, be lookin' to defend their home turf. SportsBetting3.com says bet on this game and review the odds below!

Best Chiefs at Chargers Odds


Best Point Spread Betting Odds
Underdog

Los Angeles Chargers
Favorite

Kansas City Chiefs
The Kansas City Chiefs have a -3 -118 point spread at BetMGM OH. They are the point spread favorite in this matchup. The Los Angeles Chargers have a +3 -102 point spread at BetMGM OH. The Los Angeles Chargers are the point spread underdogs. Review how to bet on a point spread with our text and video tutorials.

Best Total Betting Odds
OverUnder
BetMGM has the best over line of 45.5 points. Risk $110 to win $100. BetMGM has the best under line of 45.5 points. Risk $110 to win $100. Our tutorial explains more about total bets.

Best Moneyline Betting Odds
Underdog

Los Angeles Chargers
Favorite

Kansas City Chiefs
The Kansas City Chiefs are the -175 moneyline favorite. Risk $175 to win $100 on the Kansas City Chiefs at BetMGM. The Los Angeles Chargers are the +145 underdog at BetMGM. Risk $100 to win $145 on the Los Angeles Chargers. Learn more about how to bet on money lines.

Matchup Odds FAQs

What is the point spread for the Kansas City Chiefs vs Los Angeles Chargers NFL game on Friday, September 5th, 2025?

The Kansas City Chiefs are -3 -118 point spread favorites at BetMGM, while the Los Angeles Chargers are +3 -102 point spread underdogs at BetMGM.

What is the over-under total line for the Kansas City Chiefs vs Los Angeles Chargers NFL game on Friday, September 5th, 2025?

The best over line is 45.5 -110 points at BetMGM, which means you risk $110 to win $100 betting the over. The best under line is 45.5 -110 points at BetMGM, and that means you risk $110 to win $100 betting the under.

What is the moneyline for the Kansas City Chiefs vs Los Angeles Chargers NFL game on Friday, September 5th, 2025?

The Kansas City Chiefs are the -175 moneyline favorite at BetMGM and the Los Angeles Chargers are the +145 moneyline underdog at BetMGM.

NFL Odds Example

NFL Odds and Outcomes Explained

Game
BetMGM Sports Betting BetMGM
Bet
Chiefs
Chargers
9/05/25 8:20pm EDT
-3 -118+3 -102
Bet $100 at BetMGM Ohio
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Underdog Los Angeles Chargers - Los Angeles Chargers bettors risk $100 to win $98.04 at -102 odds.

A +3 Los Angeles Chargers underdog bet wins if they lose by 2 or fewer, tie, or win outright. The bet pushes if they lose by 3. Your bet loses if they lose by 4 or more.

Favorite Kansas City Chiefs - Kansas City Chiefs bettors risk $100 to win $84.75 at -118 odds.

A -3 Kansas City Chiefs favorite bet wins if they win by 4 or more. The bet pushes if they win by 3. Your bet loses if they win by 2 or fewer, tie, or lose outright.

Kansas City Chiefs at Los Angeles Chargers Prop Bets

NFL Prop Bets
+ Displays more odds
BetMGM Sports Betting BetMGM
Bet
Chiefs
Chargers
First Team To Score
9/05/25 8:20pm EDT
-125-102Bet
Chiefs
Chargers
No Touchdown
To Score 1st Touchdown
9/05/25 8:20pm EDT
-140+105+10000Bet
Chiefs
Chargers
Game to Overtime
9/05/25 8:20pm EDT
Yes +750No -2500Bet
Chiefs
Chargers
Safety to be Scored
9/05/25 8:20pm EDT
Yes +1000No -3000Bet
BetMGM Sports Betting BetMGM
Justin Herbert
Interceptions Thrown
KC at LAC
9/05/25 8:20pm EDT
0.5 o +1050.5 u -140Bet
Patrick Mahomes
Interceptions Thrown
KC at LAC
9/05/25 8:20pm EDT
0.5 o +1000.5 u -135Bet
Justin Herbert
Longest Passing Completion
KC at LAC
9/05/25 8:20pm EDT
35.5 o -12035.5 u -110Bet
Patrick Mahomes
Longest Passing Completion
KC at LAC
9/05/25 8:20pm EDT
36.5 o -11036.5 u -118Bet
BetMGM Sports Betting BetMGM
Cameron Dicker
Total Kicking Points
KC at LAC
9/05/25 8:20pm EDT
6.5 o -1356.5 u +100Bet
Harrison Butker
Total Kicking Points
KC at LAC
9/05/25 8:20pm EDT
7.5 o +1057.5 u -140Bet
Justin Herbert
Total Pass Completions
KC at LAC
9/05/25 8:20pm EDT
20.5 o +10020.5 u -135Bet
Patrick Mahomes
Total Pass Completions
KC at LAC
9/05/25 8:20pm EDT
23.5 o -11523.5 u -115Bet
BetMGM Sports Betting BetMGM
Justin Herbert
Total Passing Yards
KC at LAC
9/05/25 8:20pm EDT
225.5 o -115225.5 u -115Bet
Patrick Mahomes
Total Passing Yards
KC at LAC
9/05/25 8:20pm EDT
249.5 o -115249.5 u -118Bet
Justin Herbert
Total Touchdown Passes
KC at LAC
9/05/25 8:20pm EDT
1.5 o +1051.5 u -140Bet
Patrick Mahomes
Total Touchdown Passes
KC at LAC
9/05/25 8:20pm EDT
1.5 o -1501.5 u +110Bet

Recent Meetings Since 2021

Recent Meetings Since 2021
WeekGameResultMargin
2024
Week 14
Chargers vs Chiefs
Sunday, December 8th, 2024
KC 19, LAC 17
GEHA Field at Arrowhead Stadium
Chiefs by 2
2024
Week 4
Chiefs vs Chargers
Sunday, September 29th, 2024
KC 17, LAC 10
SoFi Stadium
Chiefs by 7
2023
Week 18
Chiefs vs Chargers
Sunday, January 7th, 2024
KC 13, LAC 12
SoFi Stadium
Chiefs by 1
2023
Week 7
Chargers vs Chiefs
Sunday, October 22nd, 2023
KC 31, LAC 17
GEHA Field at Arrowhead Stadium
Chiefs by 14
2022
Week 11
Chiefs vs Chargers
Sunday, November 20th, 2022
KC 30, LAC 27
SoFi Stadium
Chiefs by 3
2022
Week 2
Chargers vs Chiefs
Thursday, September 15th, 2022
KC 27, LAC 24
GEHA Field at Arrowhead Stadium
Chiefs by 3
2021
Week 15
Chiefs vs Chargers
Thursday, December 16th, 2021
KC 34, LAC 28 (OT)
SoFi Stadium
Chiefs by 6
2021
Week 3
Chargers vs Chiefs
Sunday, September 26th, 2021
LAC 30, KC 24
GEHA Field at Arrowhead Stadium
Chargers by 6

Team Standings

2025-2026 NFL Regular Season Standings - Kansas City Chiefs, Los Angeles Chargers
Team W L T Pct PF PA Home Away Div Div% Conf Conf% Strk L5
Kansas City Chiefs0000.000000-0-00-0-00-0-00.0000-0-00.0000- -
Los Angeles Chargers0000.000000-0-00-0-00-0-00.0000-0-00.0000- -

Kansas City Chiefs & Los Angeles Chargers Futures Odds

Here are each team's Super Bowl, conference, and division futures odds. Review odds for other matchups and learn the best NFL bets.

Kansas City Chiefs Futures Odds
2025-26 Kansas City Chiefs Super Bowl Odds

Team
BetMGM Sports Betting BetMGM
Chiefs
+800
Bet
Los Angeles Chargers Futures Odds
2025-26 Los Angeles Chargers Super Bowl Odds

Team
BetMGM Sports Betting BetMGM
Chargers
+2800
Bet

Kansas City Chiefs & Los Angeles Chargers Team Pages

Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Kansas City Chiefs vs Los Angeles Chargers NFL Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Friday, September 5th, 2025 at 8:20 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's NFL page, look for the Kansas City Chiefs vs Los Angeles Chargers Game.

    Navigate to the sportsbook's NFL page. Next, look for live or upcoming matchups. Select the Kansas City Chiefs vs Los Angeles Chargers Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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