Indianapolis Colts vs Los Angeles Chargers Odds

The Colts will play the Chargers on Sunday, October 19th, 2025. The matchup takes place at SoFi Stadium. Watch this exciting Week 7 matchup at 4:05 pm EDT. Check local listings for coverage on CBS.

Learn more about NFL betting with our handy tutorial and guide. Know when to bet the spread, moneyline, totals or props.


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Table of Contents

Key Matchup Stats

The Indianapolis Colts and Los Angeles Chargers will take the field at SoFi Stadium for a key Week 7 matchup on Sunday, October 19th, 2025. Have a look at each team's key performance stats below as they continue to make their way through the 2025-26 NFL regular season.

  • SportsBetting3.com Power Rankings - Heading into Week 7 of the 2025-26 season, the Indianapolis Colts have a power ranking of 99.67. Our calculations have the Los Angeles Chargers at a 94.00 power ranking.
  • Away Indianapolis Colts - Now in the middle of the season, the Indianapolis Colts have a 1-1-0 record as an away team, ranking them 3rd in the league for away team wins.
  • Home Los Angeles Chargers - The Los Angeles Chargers come to this Week 7 matchup with a 2-1-0 record as a home team. They rank 3rd in the league for home team wins so far this season.
  • Points Scored - The Indianapolis Colts currently rank 1st (194) on the edge of Week 7, with the Los Angeles Chargers ranked 17th (127) for points scored to date.
  • Points Against - The Indianapolis Colts stand 20th (116) in the middle weeks of the regular season for points against. As for the Los Angeles Chargers, they currently rank 16th (125) for points against.
  • Team Records - Standings become more important now more than ever. Approaching Week 7, the Indianapolis Colts have a 5-1-0 record, with the Los Angeles Chargers at 4-2-0 for the 2025-26 regular season.

Captain Shady Lines

A broken compass is right at least twice a day.

Captain Shady Lines
Captain Shady Lines

Avast ye, ye scurvy dogs! The Colts be facing off against the Chargers in a crucial Week 7 battle on October 19th, 2025. The Colts be standin' at 5-1-0, while the Chargers be holdin' a 4-2-0 record.

Mid-season games be vital to each team's standings in the NFL regular season. This be no time to be takin' it easy, as every win be crucial.

This clash be happenin' at the mighty SoFi Stadium, a place of grandeur and fierce competition. The city and culture be addin' to the excitement of this matchup.

The SportsBetting3.com NFL Power Rankings favor the Colts with a 99.67 score over the Chargers' 94.00. Bet this game at BetMGM or our preferred sports betting partner BetRivers, look at this game's prop bets, and compare odds from partner sports betting sites. May the best team emerge victorious in this epic showdown on the gridiron!

Best Colts at Chargers Odds


Best Point Spread Betting Odds
Underdog

Indianapolis Colts
Favorite

Los Angeles Chargers
The Los Angeles Chargers have a -2.5 -115 point spread at BetMGM OH. They are the point spread favorite in this matchup. The Indianapolis Colts have a +2.5 -105 point spread at BetMGM OH. The Indianapolis Colts are the point spread underdogs. Review how to bet on a point spread with our text and video tutorials.

Best Total Betting Odds
OverUnder
BetMGM has the best over line of 48.5 points. Risk $110 to win $100. BetMGM has the best under line of 48.5 points. Risk $110 to win $100. Our tutorial explains more about total bets.

Best Moneyline Betting Odds
Underdog

Indianapolis Colts
Favorite

Los Angeles Chargers
The Los Angeles Chargers are the -145 moneyline favorite. Risk $145 to win $100 on the Los Angeles Chargers at BetMGM. The Indianapolis Colts are the +120 underdog at BetMGM. Risk $100 to win $120 on the Indianapolis Colts. Learn more about how to bet on money lines.

Matchup Odds FAQs

What is the point spread for the Indianapolis Colts vs Los Angeles Chargers NFL game on Sunday, October 19th, 2025?

The Los Angeles Chargers are -2.5 -115 point spread favorites at BetMGM, while the Indianapolis Colts are +2.5 -105 point spread underdogs at BetMGM.

What is the over-under total line for the Indianapolis Colts vs Los Angeles Chargers NFL game on Sunday, October 19th, 2025?

The best over line is 48.5 -110 points at BetMGM, which means you risk $110 to win $100 betting the over. The best under line is 48.5 -110 points at BetMGM, and that means you risk $110 to win $100 betting the under.

What is the moneyline for the Indianapolis Colts vs Los Angeles Chargers NFL game on Sunday, October 19th, 2025?

The Los Angeles Chargers are the -145 moneyline favorite at BetMGM and the Indianapolis Colts are the +120 moneyline underdog at BetMGM.

NFL Odds Example

NFL Odds and Outcomes Explained

Game
BetMGM Sports Betting BetMGM
Bet
Colts
Chargers
10/19/25 4:05pm EDT
+2.5 -105-2.5 -115
Bet $100 at BetMGM Ohio
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Underdog Indianapolis Colts - Indianapolis Colts bettors risk $100 to win $95.24 at -105 odds.

A +2.5 Indianapolis Colts underdog bet wins if they lose by 2 or fewer, tie, or win outright. Your bet loses if they lose by 3 or more.

Favorite Los Angeles Chargers - Los Angeles Chargers bettors risk $100 to win $86.96 at -115 odds.

A -2.5 Los Angeles Chargers favorite bet wins if they win by 3 or more. Your bet loses if they win by 2 or fewer, tie, or lose outright.

Indianapolis Colts at Los Angeles Chargers Prop Bets

NFL Prop Bets
+ Displays more odds
BetMGM Sports Betting BetMGM
Bet
Colts
Chargers
First Team To Score
10/19/25 4:05pm EDT
-105-120Bet
Colts
Chargers
No Touchdown
To Score 1st Touchdown
10/19/25 4:05pm EDT
-105-125+10000Bet
Colts
Chargers
Game to Overtime
10/19/25 4:05pm EDT
Yes +675No -2000Bet
Colts
Chargers
Safety to be Scored
10/19/25 4:05pm EDT
Yes +1000No -3000Bet
BetMGM Sports Betting BetMGM
Daniel Jones
Interceptions Thrown
IND at LAC
10/19/25 4:05pm EDT
0.5 o +1050.5 u -140Bet
Justin Herbert
Interceptions Thrown
IND at LAC
10/19/25 4:05pm EDT
0.5 o +1000.5 u -130Bet
Daniel Jones
Longest Passing Completion
IND at LAC
10/19/25 4:05pm EDT
34.5 o -11534.5 u -115Bet
Justin Herbert
Longest Passing Completion
IND at LAC
10/19/25 4:05pm EDT
35.5 o -11835.5 u -110Bet
BetMGM Sports Betting BetMGM
Cameron Dicker
Total Kicking Points
IND at LAC
10/19/25 4:05pm EDT
7.5 o -1157.5 u -115Bet
Michael Badgley
Total Kicking Points
IND at LAC
10/19/25 4:05pm EDT
6.5 o -1356.5 u +105Bet
Daniel Jones
Total Pass Completions
IND at LAC
10/19/25 4:05pm EDT
20.5 o +10020.5 u -135Bet
Justin Herbert
Total Pass Completions
IND at LAC
10/19/25 4:05pm EDT
24.5 o -11824.5 u -110Bet
BetMGM Sports Betting BetMGM
Daniel Jones
Total Passing Yards
IND at LAC
10/19/25 4:05pm EDT
221.5 o -115221.5 u -118Bet
Justin Herbert
Total Passing Yards
IND at LAC
10/19/25 4:05pm EDT
262.5 o -115262.5 u -115Bet
Daniel Jones
Total Touchdown Passes
IND at LAC
10/19/25 4:05pm EDT
1.5 o +1001.5 u -135Bet
Justin Herbert
Total Touchdown Passes
IND at LAC
10/19/25 4:05pm EDT
1.5 o -1751.5 u +130Bet

Recent Meetings Since 2021

Recent Meetings Since 2021
WeekGameResultMargin
2025
Week 7
Colts vs Chargers
Sunday, October 19th, 2025
IND 38, LAC 24
SoFi Stadium
Colts by 14
2022
Week 16
Chargers vs Colts
Monday, December 26th, 2022
LAC 20, IND 3
Lucas Oil Stadium
Chargers by 17

Team Standings

2025-2026 NFL Regular Season Standings - Indianapolis Colts, Los Angeles Chargers
Team W L T Pct PF PA Home Away Div Div% Conf Conf% Strk L5
Indianapolis Colts6100.8572321404-0-02-1-01-0-01.0005-0-01.0003W4-1-0
Los Angeles Chargers4300.5711511632-2-02-1-03-0-01.0004-1-00.8001L2-3-0

Indianapolis Colts & Los Angeles Chargers Futures Odds

Here are each team's Super Bowl, conference, and division futures odds. Review odds for other matchups and learn the best NFL bets.

Indianapolis Colts Futures Odds
2025-26 Indianapolis Colts Super Bowl Odds

Team
BetMGM Sports Betting BetMGM
Colts
+1200
Bet
Los Angeles Chargers Futures Odds
2025-26 Los Angeles Chargers Super Bowl Odds

Team
BetMGM Sports Betting BetMGM
Chargers
+3000
Bet

Indianapolis Colts & Los Angeles Chargers Team Pages

Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Indianapolis Colts vs Los Angeles Chargers NFL Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Sunday, October 19th, 2025 at 4:05 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's NFL page, look for the Indianapolis Colts vs Los Angeles Chargers Game.

    Navigate to the sportsbook's NFL page. Next, look for live or upcoming matchups. Select the Indianapolis Colts vs Los Angeles Chargers Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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