The Pirates will play the Cardinals on Thursday, August 28th, 2025. Your timezone's first pitch time is 2:15 pm EDT. Check local listings or your nearest streaming app for coverage.
Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.
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Table of Contents
- Best Odds
- Interactive Odds Example
- Prop Bets
- Team Futures Odds
- Team Pages
- Team Standings
- Other Games Today
Best Pirates at Cardinals Odds
| Underdog Pittsburgh Pirates | Favorite St. Louis Cardinals |
|---|---|
| Over | Under |
|---|---|
| Underdog St. Louis Cardinals | Favorite Pittsburgh Pirates |
|---|---|
Matchup Odds FAQs
The St. Louis Cardinals are the -120 moneyline favorite at BetMGM and the Pittsburgh Pirates are the +100 moneyline underdog at BetMGM.
The best over line is 8 -120 runs at BetMGM, which means you risk $120 to win $100 betting the over. The best under line is 8 +100 runs at BetMGM, and that means you risk $100 to win $100 betting the under.
The Pittsburgh Pirates are -1.5 +165 run line favorites at BetMGM, while the St. Louis Cardinals are +1.5 -200 run line underdogs at BetMGM.
MLB Odds Example
|
Game |
 BetMGMBet |
|---|---|
Pirates
Cardinals
8/28/25 2:15pm EDT | +100-120 |
- Pittsburgh Pirates bettors risk $100 to win $100 at +100 odds. The implied probability for Pittsburgh Pirates is 50%.
- St. Louis Cardinals bettors risk $100 to win $83.33 at -120 odds. The implied probability for St. Louis Cardinals is 54.55%.
Pittsburgh Pirates at St. Louis Cardinals Prop Bets
| BetMGM Bet |
|
|---|---|
Pirates
Cardinals
First Team to Score
8/28/25 2:15pm EDT | -165+130Bet |
Pirates
Cardinals
Tie
1st Inning Winner
8/28/25 2:15pm EDT | +270+320-135Bet |
Pirates
Cardinals
Tie
First 3 Innings Winner
8/28/25 2:15pm EDT | +125+154+290Bet |
Pirates
Cardinals
To Extra Innings
8/28/25 2:15pm EDT | Yes +725No -1200Bet |
| BetMGM | |
Pirates
Cardinals
1st Team to Score Will Win
8/28/25 2:15pm EDT | Yes -250No +190Bet |
Pirates
Total Runs
PIT at STL 8/28/25 2:15pm EDT | 3.5 o -1453.5 u +110Bet |
Cardinals
Total Runs
PIT at STL 8/28/25 2:15pm EDT | 3.5 o -1503.5 u +115Bet |
Braxton Ashcraft
Strikeouts Thrown
PIT at STL 8/28/25 2:15pm EDT | 3.5 o -1753.5 u +130Bet |
| BetMGM | |
Miles Mikolas
Strikeouts Thrown
PIT at STL 8/28/25 2:15pm EDT | 3.5 o -1103.5 u -115Bet |
Pittsburgh Pirates & St. Louis Cardinals Futures Odds
Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.
Pittsburgh Pirates World Series Odds|
Team | BetMGM |
|---|---|
| Pirates |
|
Team | BetMGM |
|---|---|
| Cardinals | +100000 Bet |
Pittsburgh Pirates & St. Louis Cardinals Team Pages
Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:
Team Standings
| Team | W | L | Pct | GB | Home | Away | RS | RA | Diff | Strk | L10 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| St. Louis Cardinals | 66 | 69 | 0.489 | +17.0 | 37-32 | 29-37 | 588 | 622 | -34 | W1 | 5-5 |
| Pittsburgh Pirates | 59 | 76 | 0.437 | +24.0 | 39-30 | 20-46 | 484 | 552 | -68 | L1 | 7-3 |
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the Pittsburgh Pirates vs St. Louis Cardinals MLB Game
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Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Thursday, August 28th, 2025 at 2:15 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
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Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
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Tap to the sportsbook's MLB page, look for the Pittsburgh Pirates vs St. Louis Cardinals Game.
Navigate to the sportsbook's MLB page. Next, look for live or upcoming matchups. Select the Pittsburgh Pirates vs St. Louis Cardinals Game.
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Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.
Other August 28, 2025 MLB Games
- Boston Red Sox vs Baltimore Orioles - 8/28/25 1:05pm EDT
- Arizona Diamondbacks vs Milwaukee Brewers - 8/28/25 2:10pm EDT
- Colorado Rockies vs Houston Astros - 8/28/25 2:10pm EDT
- Chicago Cubs vs San Francisco Giants - 8/28/25 3:45pm EDT
- Atlanta Braves vs Philadelphia Phillies - 8/28/25 6:45pm EDT
- Miami Marlins vs New York Mets - 8/28/25 7:10pm EDT
- New York Yankees vs Chicago White Sox - 8/28/25 7:40pm EDT