Oakland Athletics vs Houston Astros Odds

The Athletics will play the Astros on Wednesday, May 28th, 2025. Your timezone's first pitch time is 2:10 pm EDT. Check local listings or your nearest streaming app for coverage.

Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.


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Table of Contents

Key Matchup Stats

  • SportsBetting3.com Power Rankings - As the 2025 season continues, the Oakland Athletics possess a 86.67 SportsBetting3.com power ranking. The Houston Astros now have a 94.33 power ranking. Teams with a higher SportsBetting3.com power ranking will typically be moneyline favorites.
  • Visiting Oakland Athletics - The Oakland Athletics head into this matchup with a 14-12 record as a visiting team. This standing ranks them 4th Overall for visiting team wins.
  • Home Houston Astros - The Houston Astros will throw the first pitch possessing a 18-10 home team record. That puts them 3rd for home team wins in the Overall MLB standings.
  • Runs Scored - Oakland Athletics batters have produced 231 runs, ranking them 13th Overall, with the Houston Astros ranking 17th (214) for runs scored.
  • Runs Allowed - Oakland Athletics pitchers and fielders have allowed 308 runs, ranking them 2nd Overall for runs allowed. Meanwhile, the Houston Astros now rank 22nd Overall, allowing 190 runs.
  • Team Streaks - The Oakland Athletics won their last game. Their opponent, the Houston Astros have won their last 2 games.
  • Team Records - Let's review each team's records. The Oakland Athletics have a 23-31 Overall record (7.0 GB American West Division), with the Houston Astros notching a 28-25 Overall standing (1.5 GB American West Division).

Captain Shady Lines

A broken compass is right at least twice a day.

Captain Shady Lines
Captain Shady Lines

Avast, ye scallywags! The Oakland Athletics be playin' the Houston Astros on Wednesday...

Them A's be playin' like landlubbers with their sorry record lately...

But don't count 'em out just yet, they be lookin' to plunder...

Will the Astros be walkin' the plank or sendin' the A's to Davy Jones' locker?...

Check out this game's prop bets below and bet on MLB baseball at legal US sportsbooks...

The Astros be holdin' a better record, but anythin' can happen on the high seas...

The A's be needin' to shape up or it'll be a long voyage ahead...

Review each team's standing at the bottom of the page and may the best team win!

Best Athletics at Astros Odds


Best Moneyline Betting Odds
Underdog

Oakland Athletics
Favorite

Houston Astros
The Houston Astros are the -145 moneyline favorite. Risk $145 to win $100 on the Houston Astros at BetMGM. The Oakland Athletics are the +118 underdog at BetMGM. Risk $100 to win $118 on the Oakland Athletics. Learn more about how to bet on money lines.

Best Total Betting Odds
OverUnder
BetMGM has the best over line of 8.5 runs. Risk $100 to win $100. BetMGM has the best under line of 8.5 runs. Risk $120 to win $100. Our tutorial explains more about total bets.

Best Run Line Betting Odds
Underdog

Oakland Athletics
Favorite

Houston Astros
The Houston Astros have a -1.5 +145 run line at BetMGM OH. They are the run line favorite in this matchup. The Oakland Athletics have a +1.5 -175 run line at BetMGM OH. The Oakland Athletics are the run line underdogs. Review how to bet on a point spread with our text and video tutorials.

Matchup Odds FAQs

What is the moneyline for the Oakland Athletics vs Houston Astros MLB game on Wednesday, May 28th, 2025?

The Houston Astros are the -145 moneyline favorite at BetMGM and the Oakland Athletics are the +118 moneyline underdog at BetMGM.

What is the over-under total line for the Oakland Athletics vs Houston Astros MLB game on Wednesday, May 28th, 2025?

The best over line is 8.5 +100 runs at BetMGM, which means you risk $100 to win $100 betting the over. The best under line is 8.5 -120 runs at BetMGM, and that means you risk $120 to win $100 betting the under.

What is the run line for the Oakland Athletics vs Houston Astros MLB game on Wednesday, May 28th, 2025?

The Houston Astros are -1.5 +145 run line favorites at BetMGM, while the Oakland Athletics are +1.5 -175 run line underdogs at BetMGM.

MLB Odds Example

MLB Odds and Outcomes Explained

Game
BetMGM Sports Betting BetMGM
Bet
Athletics
Astros
5/28/25 2:10pm EDT
+118-145
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Possible Moneyline Outcomes
  • Oakland Athletics bettors risk $100 to win $118 at +118 odds. The implied probability for Oakland Athletics is 45.87%.
  • Houston Astros bettors risk $100 to win $68.97 at -145 odds. The implied probability for Houston Astros is 59.18%.

Oakland Athletics at Houston Astros Prop Bets

MLB Prop Bets
+ Displays more odds
BetMGM Sports Betting BetMGM
Bet
Athletics
Astros
First Team to Score
5/28/25 2:10pm EDT
-150+118Bet
Athletics
Astros
Tie
1st Inning Winner
5/28/25 2:10pm EDT
+300+290-135Bet
Athletics
Astros
Tie
First 3 Innings Winner
5/28/25 2:10pm EDT
+150+135+280Bet
Athletics
Astros
To Extra Innings
5/28/25 2:10pm EDT
Yes +750No -1200Bet
BetMGM Sports Betting BetMGM
Athletics
Astros
1st Team to Score Will Win
5/28/25 2:10pm EDT
Yes -250No +190Bet
Astros
Total Runs
OAK at HOU
5/28/25 2:10pm EDT
4.5 o +1104.5 u -145Bet
Lance McCullers Jr
Strikeouts Thrown
OAK at HOU
5/28/25 2:10pm EDT
4.5 o -1454.5 u +110Bet
Luis Severino
Strikeouts Thrown
OAK at HOU
5/28/25 2:10pm EDT
4.5 o +1004.5 u -130Bet

Oakland Athletics & Houston Astros Futures Odds

Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.

Oakland Athletics World Series Odds
2025 Oakland Athletics World Series Odds

Team
BetMGM Sports Betting BetMGM
Athletics
+50000
Bet
Houston Astros World Series Odds
2025 Houston Astros World Series Odds

Team
BetMGM Sports Betting BetMGM
Astros
+1100
Bet

Oakland Athletics & Houston Astros Team Pages

Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Standings

2025 MLB Regular Season Standings - Oakland Athletics, Houston Astros
Team W L Pct GB Home Away RS RA Diff Strk L10
Houston Astros28250.528+6.518-1010-15214190+24W26-4
Oakland Athletics23310.426+12.09-1914-12231308-77W11-9

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Oakland Athletics vs Houston Astros MLB Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Wednesday, May 28th, 2025 at 2:10 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's MLB page, look for the Oakland Athletics vs Houston Astros Game.

    Navigate to the sportsbook's MLB page. Next, look for live or upcoming matchups. Select the Oakland Athletics vs Houston Astros Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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