The Astros will play the Diamondbacks on Wednesday, July 23rd, 2025. Your timezone's first pitch time is 3:40 pm EDT. Check local listings or your nearest streaming app for coverage.
Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.
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Table of Contents
- Best Odds
- Interactive Odds Example
- Prop Bets
- Team Futures Odds
- Team Pages
- Team Standings
- Other Games Today
Best Astros at Diamondbacks Odds
| Underdog Houston Astros | Favorite Arizona Diamondbacks |
|---|---|
| Over | Under |
|---|---|
| Underdog Houston Astros | Favorite Arizona Diamondbacks |
|---|---|
Matchup Odds FAQs
The Arizona Diamondbacks are the -135 moneyline favorite at BetMGM and the Houston Astros are the +115 moneyline underdog at BetMGM.
The best over line is 8.5 +100 runs at BetMGM, which means you risk $100 to win $100 betting the over. The best under line is 8.5 -120 runs at BetMGM, and that means you risk $120 to win $100 betting the under.
The Arizona Diamondbacks are -1.5 +155 run line favorites at BetMGM, while the Houston Astros are +1.5 -190 run line underdogs at BetMGM.
MLB Odds Example
|
Game |
 BetMGMBet |
|---|---|
Astros
Diamondbacks
7/23/25 3:40pm EDT | +115-135 |
- Houston Astros bettors risk $100 to win $115 at +115 odds. The implied probability for Houston Astros is 46.51%.
- Arizona Diamondbacks bettors risk $100 to win $74.07 at -135 odds. The implied probability for Arizona Diamondbacks is 57.45%.
Houston Astros at Arizona Diamondbacks Prop Bets
| BetMGM Bet |
|
|---|---|
Astros
Diamondbacks
First Team to Score
7/23/25 3:40pm EDT | -125-102Bet |
Astros
Diamondbacks
Tie
1st Inning Winner
7/23/25 3:40pm EDT | +340+275-145Bet |
Astros
Diamondbacks
Tie
First 3 Innings Winner
7/23/25 3:40pm EDT | +175+120+270Bet |
Astros
Diamondbacks
To Extra Innings
7/23/25 3:40pm EDT | Yes +750No -1200Bet |
| BetMGM | |
Astros
Diamondbacks
1st Team to Score Will Win
7/23/25 3:40pm EDT | Yes -250No +190Bet |
Diamondbacks
Total Runs
HOU at ARI 7/23/25 3:40pm EDT | 4.5 o +1104.5 u -145Bet |
Astros
Total Runs
HOU at ARI 7/23/25 3:40pm EDT | 3.5 o -1403.5 u +105Bet |
Brandon Pfaadt
Strikeouts Thrown
HOU at ARI 7/23/25 3:40pm EDT | 5.5 o -1055.5 u -120Bet |
| BetMGM | |
Brandon Walter
Strikeouts Thrown
HOU at ARI 7/23/25 3:40pm EDT | 4.5 o +1154.5 u -150Bet |
Houston Astros & Arizona Diamondbacks Futures Odds
Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.
Houston Astros World Series Odds|
Team | BetMGM |
|---|---|
| Astros | +1600 Bet |
|
Team | BetMGM |
|---|---|
| Diamondbacks | +100000 Bet |
Houston Astros & Arizona Diamondbacks Team Pages
Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:
Team Standings
| Team | W | L | Pct | GB | Home | Away | RS | RA | Diff | Strk | L10 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Houston Astros | 74 | 60 | 0.552 | +8.5 | 40-28 | 34-32 | 569 | 550 | +19 | W2 | 5-5 |
| Arizona Diamondbacks | 66 | 69 | 0.489 | +17.0 | 34-32 | 32-37 | 667 | 657 | +10 | W2 | 6-4 |
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the Houston Astros vs Arizona Diamondbacks MLB Game
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Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Wednesday, July 23rd, 2025 at 3:40 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
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Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
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Tap to the sportsbook's MLB page, look for the Houston Astros vs Arizona Diamondbacks Game.
Navigate to the sportsbook's MLB page. Next, look for live or upcoming matchups. Select the Houston Astros vs Arizona Diamondbacks Game.
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Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.
Other July 23, 2025 MLB Games
- Cincinnati Reds vs Washington Nationals
- San Diego Padres vs Miami Marlins
- San Francisco Giants vs Atlanta Braves
- Detroit Tigers vs Pittsburgh Pirates
- Los Angeles Angels vs New York Mets
- Kansas City Royals vs Chicago Cubs
- St. Louis Cardinals vs Colorado Rockies
- Milwaukee Brewers vs Seattle Mariners
- Minnesota Twins vs Los Angeles Dodgers
- Baltimore Orioles vs Cleveland Guardians
- Boston Red Sox vs Philadelphia Phillies
- New York Yankees vs Toronto Blue Jays
- Chicago White Sox vs Tampa Bay Rays
- Oakland Athletics vs Texas Rangers