The Cubs will play the Padres on Wednesday, April 16th, 2025. Your timezone's first pitch time is 4:10 pm EDT. Check local listings or your nearest streaming app for coverage.
Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.
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Table of Contents
- Matchup Stats
- Captain Shady Lines
- Best Odds
- Interactive Odds Example
- Prop Bets
- Team Futures Odds
- Team Pages
- Team Standings
- Other Games Today
Key Matchup Stats
- SportsBetting3.com Power Rankings - The Chicago Cubs have a 97.00 power ranking. The power ranking for the San Diego Padres is 99.67.
- Visiting Chicago Cubs - The Chicago Cubs have a 7-4 record as a visiting team, ranking them 2nd Overall for visiting team wins.
- Home San Diego Padres - The San Diego Padres have a 11-0 record as a home team. They rank 1st for home team wins in the Overall standings.
- Runs Scored - The Chicago Cubs currently stand 1st (120) Overall, with the San Diego Padres ranking 5th (83) for runs scored.
- Runs Allowed - The Chicago Cubs are 4th (83) Overall for runs allowed. The San Diego Padres stand 24th (47) for runs allowed.
- Team Streaks - The Chicago Cubs lost their last game. Meanwhile, the San Diego Padres have won their last 5 games.
- Team Records - The Chicago Cubs have a 11-8 Overall record (0.0 GB National Central Division), with the San Diego Padres possessing a 14-3 Overall standing (0.0 GB National West Division).
Captain Shady Lines
A broken compass is right at least twice a day.
Avast ye scallywags! The Cubs be sailin' into enemy territory on Wednesday...
They be facin' the formidable Padres, who be holdin' a mighty record...
If ye be daring enough, head over to SportsBetting3.com and bet on this game... (Yar har har!)...
The odds be stacked against the Cubs, but never underestimate the heart of a pirate...
Review the odds below, and place yer bets wisely, me hearties! Good luck!
Best Cubs at Padres Odds
| Underdog Chicago Cubs | Favorite San Diego Padres |
|---|---|
| Over | Under |
|---|---|
| Underdog San Diego Padres | Favorite Chicago Cubs |
|---|---|
Matchup Odds FAQs
The San Diego Padres are the -120 moneyline favorite at BetMGM and the Chicago Cubs are the +100 moneyline underdog at BetMGM.
The best over line is 7.5 -115 runs at BetMGM, which means you risk $115 to win $100 betting the over. The best under line is 7.5 -105 runs at BetMGM, and that means you risk $105 to win $100 betting the under.
The Chicago Cubs are -1.5 +170 run line favorites at BetMGM, while the San Diego Padres are +1.5 -210 run line underdogs at BetMGM.
MLB Odds Example
|
Game |
 BetMGMBet |
|---|---|
Cubs
Padres
4/16/25 4:10pm EDT | +100-120 |
- Chicago Cubs bettors risk $100 to win $100 at +100 odds. The implied probability for Chicago Cubs is 50%.
- San Diego Padres bettors risk $100 to win $83.33 at -120 odds. The implied probability for San Diego Padres is 54.55%.
Chicago Cubs at San Diego Padres Prop Bets
| BetMGM Bet |
|
|---|---|
Cubs
Padres
First Team to Score
4/16/25 4:10pm EDT | -145+110Bet |
Cubs
Padres
Tie
1st Inning Winner
4/16/25 4:10pm EDT | +320+300-145Bet |
Cubs
Padres
Tie
First 3 Innings Winner
4/16/25 4:10pm EDT | +154+135+260Bet |
Cubs
Padres
To Extra Innings
4/16/25 4:10pm EDT | Yes +700No -1100Bet |
| BetMGM | |
Cubs
Padres
1st Team to Score Will Win
4/16/25 4:10pm EDT | Yes -250No +190Bet |
Cubs
Total Runs
CUB at SDG 4/16/25 4:10pm EDT | 3.5 o -1303.5 u -102Bet |
Padres
Total Runs
CUB at SDG 4/16/25 4:10pm EDT | 3.5 o -1303.5 u -102Bet |
Matthew Boyd
Strikeouts Thrown
CUB at SDG 4/16/25 4:10pm EDT | 4.5 o -1354.5 u +100Bet |
| BetMGM | |
Nick Pivetta
Strikeouts Thrown
CUB at SDG 4/16/25 4:10pm EDT | 5.5 o -1555.5 u +120Bet |
Chicago Cubs & San Diego Padres Futures Odds
Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.
Chicago Cubs World Series Odds|
Team | BetMGM |
|---|---|
| Cubs | +2000 Bet |
|
Team | BetMGM |
|---|---|
| Padres | +2000 Bet |
Chicago Cubs & San Diego Padres Team Pages
Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:
Team Standings
| Team | W | L | Pct | GB | Home | Away | RS | RA | Diff | Strk | L10 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| San Diego Padres | 17 | 11 | 0.607 | +2.5 | 12-4 | 5-7 | 106 | 83 | +23 | L4 | 3-7 |
| Chicago Cubs | 17 | 12 | 0.586 | +3.0 | 9-7 | 8-5 | 172 | 133 | +39 | L2 | 6-4 |
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the Chicago Cubs vs San Diego Padres MLB Game
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Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Wednesday, April 16th, 2025 at 4:10 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
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Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
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Tap to the sportsbook's MLB page, look for the Chicago Cubs vs San Diego Padres Game.
Navigate to the sportsbook's MLB page. Next, look for live or upcoming matchups. Select the Chicago Cubs vs San Diego Padres Game.
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Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.
Other April 16, 2025 MLB Games
- Atlanta Braves vs Toronto Blue Jays - 4/16/25 1:07pm EDT
- Detroit Tigers vs Milwaukee Brewers - 4/16/25 1:10pm EDT
- New York Mets vs Minnesota Twins - 4/16/25 1:10pm EDT
- Houston Astros vs St. Louis Cardinals - 4/16/25 1:15pm EDT
- Cleveland Guardians vs Baltimore Orioles - 4/16/25 6:35pm EDT
- Washington Nationals vs Pittsburgh Pirates - 4/16/25 6:40pm EDT
- Seattle Mariners vs Cincinnati Reds - 4/16/25 6:40pm EDT
- Arizona Diamondbacks vs Miami Marlins - 4/16/25 6:40pm EDT
- San Francisco Giants vs Philadelphia Phillies - 4/16/25 6:45pm EDT
- Kansas City Royals vs New York Yankees - 4/16/25 7:05pm EDT
- Boston Red Sox vs Tampa Bay Rays - 4/16/25 7:05pm EDT
- Oakland Athletics vs Chicago White Sox - 4/16/25 7:40pm EDT
- Los Angeles Angels vs Texas Rangers - 4/16/25 8:08pm EDT
- Colorado Rockies vs Los Angeles Dodgers - 4/16/25 10:10pm EDT