Louisville vs Syracuse Football Odds

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The Cardinals will play the Orange on Saturday, October 17th, 2026. The matchup takes place at JMA Wireless Dome. Watch this exciting Week 7 matchup at 7:30 pm EDT. Check local listings for coverage on ACC Network.

Learn more about College Football betting with our handy tutorial and guide. We explain spread, total and money line bets.


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Table of Contents

Key Matchup Stats

We're now well into the 2026 college football season. Week 7 action features a matchup between Louisville and Syracuse taking place at JMA Wireless Dome. The following are some key season stats to help you size up this game.

  • SportsBetting3.com Power Rankings - Louisville has a 95.33 conference power ranking for the 2026 season. The conference power ranking for Syracuse is 94.33.
  • Away Louisville - Heading into Week 7, Louisville currently has a 0-1 record as an away team for the 2026 regular season. This ranks them 4th in the ACC Conference for away team wins. Watch this stat carefully as the season progresses.
  • Home Syracuse - Syracuse has a 1-1 record as a home team. Looking ahead to this 2026 Week 7 matchup, they rank 4th in the ACC Conference for home team wins. Like the Louisville away record and ranking, you should continually keep tabs on this stat.
  • Points Scored - For the 2026 season, Louisville ranks 2nd (237) in the ACC Conference, with Syracuse currently ranking 12th (139) for points scored in the ACC Conference.
  • Points Against - Also in 2026, Louisville stands 2nd (166) in the ACC Conference for points scored by opponents in 2026. Syracuse sits at 10th (92) in the ACC Conference for points against in the 2026 season so far.
  • Team Records - Louisville has a 3-3 overall record for the 2026 regular season, with Syracuse currently 2-2 for the 2026 NCAAF regular season.

Best Cardinals at Orange Odds


Best Point Spread Betting Odds
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Best Total Betting Odds
OverUnder
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Best Moneyline Betting Odds
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Louisville at Syracuse Prop Bets

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College Football Prop Bets
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Louisville
Syracuse
10/17/26 7:30pm EDT
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Recent Meetings Since 2022

Recent Meetings Since 2022
WeekGameResultMargin
2026
Week 7		Louisville vs Syracuse
Saturday, October 17th, 2026		LOU 34, SYR 26
JMA Wireless Dome		Louisville by 8
2022
Week 1		Louisville vs Syracuse
Saturday, September 3rd, 2022		SYR 31, LOU 7
JMA Wireless Dome		Syracuse by 24

Team Standings

2026-2027 College Football Regular Season Standings - Louisville, Syracuse
Team Conf Conf% W L PF PA Home Away Strk
Louisville3-25.000432711923-11-1W2
Syracuse0-20.00022139921-11-1W1

Louisville & Syracuse Futures Odds

Latest NCAA Championship odds, if available, for each team. Review odds for other teams and learn the best College Football bets.

Louisville Championship Odds

No NCAA College Football Championship TM Louisville YR: futures available

Syracuse Championship Odds

No NCAA College Football Championship TM Syracuse YR: futures available

Louisville & Syracuse Team Pages

Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Schedules & Results


2026-27 Louisville Games & Results
WeekMatchupDate & Result
Week 1Louisville vs
Ole Miss		MISS 41, LOU 38
Sunday, September 6th, 2026
Week 2Villanova vs
Louisville		LOU 59, VILL 13
Friday, September 11th, 2026
Week 3SMU vs
Louisville		LOU 41, SMU 31
Saturday, September 19th, 2026
Week 4Wake Forest vs
Louisville		WAKE 30, LOU 27
Saturday, September 26th, 2026
Week 5Louisville vs
NC State		NCSU 31, LOU 28
Saturday, October 3rd, 2026
Week 6Florida State vs
Louisville		LOU 44, FSU 20
Friday, October 9th, 2026
Week 7Louisville vs
Syracuse		LOU 34, SYR 26
Saturday, October 17th, 2026
Week 9Stanford vs
Louisville		Saturday, October 31st, 2026
3:15 pm EDT
Week 10Louisville vs
Georgia Tech		Saturday, November 7th, 2026
7:30 pm EST
Week 11Louisville vs
North Carolina		Saturday, November 14th, 2026
12:00 am EST
Week 12Pittsburgh vs
Louisville		Saturday, November 21st, 2026
12:00 am EST
Week 13Louisville vs
Kentucky		Saturday, November 28th, 2026
12:00 am EST


2026-27 Syracuse Games & Results
WeekMatchupDate & Result
Week 1New Hampshire vs
Syracuse		SYR 66, UNH 3
Saturday, September 5th, 2026
Week 2California vs
Syracuse		CAL 21, SYR 18
Saturday, September 12th, 2026
Week 3Syracuse vs
Pittsburgh		PITT 27, SYR 13
Thursday, September 17th, 2026
Week 5Syracuse vs
UConn		SYR 42, CONN 41 (OT)
Saturday, October 3rd, 2026
Week 6Syracuse vs
Virginia		UVA 28, SYR 25
Saturday, October 10th, 2026
Week 7Louisville vs
Syracuse		LOU 34, SYR 26
Saturday, October 17th, 2026
Week 8Syracuse vs
North Carolina		SYR 31, UNC 30 (OT)
Saturday, October 24th, 2026
Week 9SMU vs
Syracuse		Saturday, October 31st, 2026
12:00 pm EDT
Week 10Clemson vs
Syracuse		Saturday, November 7th, 2026
12:00 pm EST
Week 11Syracuse vs
NC State		Saturday, November 14th, 2026
12:00 am EST
Week 12Syracuse vs
Boston College		Saturday, November 21st, 2026
12:00 am EST
Week 13Notre Dame vs
Syracuse		Saturday, November 28th, 2026
12:00 am EST

How to Bet on the Game

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How to Bet on the Louisville vs Syracuse College Football Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Saturday, October 17th, 2026 at 7:30 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's College Football page, look for the Louisville vs Syracuse Game.

    Navigate to the sportsbook's College Football page. Next, look for live or upcoming matchups. Select the Louisville vs Syracuse Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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