The Guardians will play the Diamondbacks on Wednesday, August 20th, 2025. Your timezone's first pitch time is 3:40 pm EDT. Check local listings or your nearest streaming app for coverage.
Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.
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Table of Contents
- Best Odds
- Interactive Odds Example
- Prop Bets
- Team Futures Odds
- Team Pages
- Team Standings
- Other Games Today
Best Guardians at Diamondbacks Odds
Underdog Cleveland Guardians | Favorite Arizona Diamondbacks |
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Over | Under |
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Underdog Arizona Diamondbacks | Favorite Cleveland Guardians |
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Matchup Odds FAQs
The Arizona Diamondbacks are the -120 moneyline favorite at BetMGM and the Cleveland Guardians are the +100 moneyline underdog at BetMGM.
The best over line is 9 -120 runs at BetMGM, which means you risk $120 to win $100 betting the over. The best under line is 9 +100 runs at BetMGM, and that means you risk $100 to win $100 betting the under.
The Cleveland Guardians are -1.5 +165 run line favorites at BetMGM, while the Arizona Diamondbacks are +1.5 -200 run line underdogs at BetMGM.
MLB Odds Example
Game |
![]() Bet |
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Guardians
Diamondbacks
8/20/25 3:40pm EDT | +100-120 |
- Cleveland Guardians bettors risk $100 to win $100 at +100 odds. The implied probability for Cleveland Guardians is 50%.
- Arizona Diamondbacks bettors risk $100 to win $83.33 at -120 odds. The implied probability for Arizona Diamondbacks is 54.55%.
Cleveland Guardians at Arizona Diamondbacks Prop Bets
![]() Bet |
|
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Guardians
Diamondbacks
First Team to Score
8/20/25 3:40pm EDT | -150+118Bet |
Guardians
Diamondbacks
Tie
1st Inning Winner
8/20/25 3:40pm EDT | +290+240-110Bet |
Guardians
Diamondbacks
Tie
First 3 Innings Winner
8/20/25 3:40pm EDT | +150+115+350Bet |
Guardians
Diamondbacks
To Extra Innings
8/20/25 3:40pm EDT | Yes +825No -1400Bet |
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Guardians
Diamondbacks
1st Team to Score Will Win
8/20/25 3:40pm EDT | Yes -250No +190Bet |
Diamondbacks
Total Runs
CLE at ARI 8/20/25 3:40pm EDT | 4.5 o -1104.5 u -118Bet |
Guardians
Total Runs
CLE at ARI 8/20/25 3:40pm EDT | 4.5 o -1104.5 u -118Bet |
Brandon Pfaadt
Strikeouts Thrown
CLE at ARI 8/20/25 3:40pm EDT | 4.5 o -1104.5 u -118Bet |
Cleveland Guardians & Arizona Diamondbacks Futures Odds
Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.
Cleveland Guardians World Series Odds
Team | ![]() |
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Guardians | +30000 Bet |
Team | ![]() |
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Diamondbacks | +100000 Bet |
Cleveland Guardians & Arizona Diamondbacks Team Pages
Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:
Team Standings
Team | W | L | Pct | GB | Home | Away | RS | RA | Diff | Strk | L10 |
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Cleveland Guardians | 66 | 66 | 0.500 | +15.5 | 33-32 | 33-34 | 508 | 563 | -55 | W2 | 3-7 |
Arizona Diamondbacks | 66 | 69 | 0.489 | +17.0 | 34-32 | 32-37 | 667 | 657 | +10 | W2 | 6-4 |
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the Cleveland Guardians vs Arizona Diamondbacks MLB Game
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Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Wednesday, August 20th, 2025 at 3:40 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
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Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
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Tap to the sportsbook's MLB page, look for the Cleveland Guardians vs Arizona Diamondbacks Game.
Navigate to the sportsbook's MLB page. Next, look for live or upcoming matchups. Select the Cleveland Guardians vs Arizona Diamondbacks Game.
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Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.
Other August 20, 2025 MLB Games
- Toronto Blue Jays vs Pittsburgh Pirates - 8/20/25 12:35pm EDT
- Seattle Mariners vs Philadelphia Phillies - 8/20/25 1:05pm EDT
- Houston Astros vs Detroit Tigers - 8/20/25 1:10pm EDT
- St. Louis Cardinals vs Miami Marlins - 8/20/25 6:40pm EDT
- New York Mets vs Washington Nationals - 8/20/25 6:45pm EDT
- Chicago White Sox vs Atlanta Braves - 8/20/25 7:15pm EDT
- New York Yankees vs Tampa Bay Rays - 8/20/25 7:35pm EDT
- Texas Rangers vs Kansas City Royals - 8/20/25 7:40pm EDT
- Oakland Athletics vs Minnesota Twins - 8/20/25 7:40pm EDT
- Milwaukee Brewers vs Chicago Cubs - 8/20/25 8:05pm EDT
- Los Angeles Dodgers vs Colorado Rockies - 8/20/25 8:40pm EDT
- Cincinnati Reds vs Los Angeles Angels - 8/20/25 9:38pm EDT
- San Francisco Giants vs San Diego Padres - 8/20/25 9:40pm EDT