Arizona Cardinals vs Buffalo Bills Odds

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The Cardinals will play the Bills on Sunday, September 8th, 2024. The matchup takes place at Highmark Stadium. Watch this exciting Week 1 matchup at 1:00 pm EDT. Check local listings for coverage on CBS.

Learn more about NFL betting with our handy tutorial and guide. Know when to bet the spread, moneyline, totals or props.


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Table of Contents

Key Matchup Stats

It's early in the 2024-25 NFL regular season for the Arizona Cardinals and Buffalo Bills. Let's review some stats from the 2023 regular season to get an idea of how these teams will fare.

  • SportsBetting3.com Power Rankings - The Arizona Cardinals had a 87.33 power ranking in the 2023 regular season. The power ranking for the Buffalo Bills in the 2023 regular season was 98.33.
  • Away Arizona Cardinals - At the end of the 2023 regular season, the Arizona Cardinals had a 2-7-0 record as an away team, ranking them 6th in the regular season for away team wins.
  • Home Buffalo Bills - The Buffalo Bills finished the 2023 regular season with a 7-2-0 record as a home team. They ranked 2nd for home team wins in the regular season standings.
  • Points Scored - The Arizona Cardinals wound up 22nd (330) in the regular season, with the Buffalo Bills ranked 6th (451) for points scored in the 2023 regular season.
  • Points Against - The Arizona Cardinals finished 2nd (455) in the regular season for points against. The Buffalo Bills wound up 28th (311) in the 2023 regular season for points against.
  • Team Records - The Arizona Cardinals had a 4-13-0 regular season record, with the Buffalo Bills notching a 11-6-0 regular season standing last year.

Captain Shady Lines

A broken compass is right at least twice a day.

Captain Shady Lines
Captain Shady Lines

Avast ye scallywags! The Arizona Cardinals be sailin' to Highmark Stadium to battle the Bills. The Cardinals be lookin' to plunder a win after a dismal season.

But beware, the Bills be a fierce foe, with a strong record last season. The battle between these two teams be sure to be a nail-biter.

If ye be feelin' lucky, head over to SportsBetting3.com to bet on this game. Ye can review the odds below and put yer doubloons on the line. May the best team win on the gridiron!

Best Cardinals at Bills Odds


Best Point Spread Betting Odds
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Best Total Betting Odds
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Best Moneyline Betting Odds
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NFL Odds Example

NFL Odds and Outcomes Explained
Game Book

Arizona Cardinals at Buffalo Bills Prop Bets

NFL Prop Bets
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Cardinals
Bills
9/08/24 1:00pm EDT
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Recent Meetings Since 2020

Recent Meetings Since 2020
WeekGameResultMargin
2024
Week 1		Cardinals vs Bills
Sunday, September 8th, 2024		BUF 34, ARI 28
Highmark Stadium		Bills by 6
2020
Week 10		Bills vs Cardinals
Sunday, November 15th, 2020		ARI 32, BUF 30
State Farm Stadium		Cardinals by 2

Team Standings

2024-2025 NFL Regular Season Standings - Arizona Cardinals, Buffalo Bills
Team W L T Pct PF PA Home Away Div Div% Conf Conf% Strk L5
xz - Buffalo Bills13400.7655253688-0-05-4-05-1-00.8339-3-00.7501L3-2-0
Arizona Cardinals8900.4714003796-3-02-6-03-3-00.5004-8-00.3331W2-3-0

Arizona Cardinals & Buffalo Bills Futures Odds

Here are each team's Super Bowl, conference, and division futures odds. Review odds for other matchups and learn the best NFL bets.

Arizona Cardinals Futures Odds

No Super Bowl TM Arizona Cardinals YR: futures available

Buffalo Bills Futures Odds

No Super Bowl TM Buffalo Bills YR: futures available

Arizona Cardinals & Buffalo Bills Team Pages

Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Arizona Cardinals vs Buffalo Bills NFL Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Sunday, September 8th, 2024 at 1:00 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's NFL page, look for the Arizona Cardinals vs Buffalo Bills Game.

    Navigate to the sportsbook's NFL page. Next, look for live or upcoming matchups. Select the Arizona Cardinals vs Buffalo Bills Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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