SMU vs Louisville Football Odds

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The Mustangs will play the Cardinals on Saturday, September 19th, 2026. The matchup takes place at L&N Federal Credit Union Stadium. Watch this exciting Week 3 matchup at 3:30 pm EDT. Check local listings for coverage on ESPN2.

Learn more about College Football betting with our handy tutorial and guide. We explain spread, total and money line bets.


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Table of Contents

Key Matchup Stats

The 2026 college football season continues with SMU matching up against Louisville at L&N Federal Credit Union Stadium. Let's review how each team is doing so far to better understand how this game will play out.

  • SportsBetting3.com Power Rankings - SMU has a 98.33 conference power ranking for the 2026 season so far. The 2026 conference power ranking for Louisville is 97.00.
  • Away SMU - SMU currently has a 1-0 record as an away team for the 2026 regular season, ranking them 1st in the ACC Conference for away team wins. Not much can be concluded from this stat just yet, so stay tuned.
  • Home Louisville - So far, Louisville has a 1-0 record as a home team. They currently rank 2nd in the ACC Conference for home team wins in 2026. Keep tabs on this figure, as it will change in the coming weeks.
  • Points Scored - SMU ranks 6th (83) in the ACC Conference, with Louisville currently ranking 3rd (97) for points scored in the 2026 ACC Conference.
  • Points Against - SMU stands 9th (34) in the ACC Conference for points scored by opponents in 2026. Louisville sits at 6th (54) in the 2026 ACC Conference for points against in the 2026 season.
  • Team Records - SMU has a 2-0 regular season overall record, with Louisville currently possessing a 1-1 regular season standing for the 2026 NCAAF season.

Best Mustangs at Cardinals Odds


Best Point Spread Betting Odds
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Point Spread odds are updating, please check back soon.

Best Total Betting Odds
OverUnder
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Best Moneyline Betting Odds
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Moneyline odds are updating, please check back soon.

College Football Odds Example

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SMU at Louisville Prop Bets

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College Football Prop Bets
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SMU
Louisville
9/19/26 3:30pm EDT
Pending

Recent Meetings Since 2022

Recent Meetings Since 2022
WeekGameResultMargin
2026
Week 3		SMU vs Louisville
Saturday, September 19th, 2026		LOU 41, SMU 31
L&N Federal Credit Union Stadium		Louisville by 10
2025
Week 13		Louisville vs SMU
Saturday, November 22nd, 2025		SMU 38, LOU 6
Gerald J. Ford Stadium		SMU by 32
2024
Week 6		SMU vs Louisville
Saturday, October 5th, 2024		SMU 34, LOU 27
L&N Federal Credit Union Stadium		SMU by 7

Team Standings

2026-2027 College Football Regular Season Standings - SMU, Louisville
Team Conf Conf% W L PF PA Home Away Strk
SMU5-24.000723332066-01-2W1
Louisville5-23.000633672334-12-1W4

SMU & Louisville Futures Odds

Latest NCAA Championship odds, if available, for each team. Review odds for other teams and learn the best College Football bets.

SMU Championship Odds

No NCAA College Football Championship TM SMU YR: futures available

Louisville Championship Odds

No NCAA College Football Championship TM Louisville YR: futures available

SMU & Louisville Team Pages

Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Schedules & Results


2026-27 SMU Games & Results
WeekMatchupDate & Result
Week 1SMU vs
Florida State		SMU 27, FSU 24
Monday, September 7th, 2026
Week 2UC Davis vs
SMU		SMU 56, UCD 10
Saturday, September 12th, 2026
Week 3SMU vs
Louisville		LOU 41, SMU 31
Saturday, September 19th, 2026
Week 4Missouri State vs
SMU		SMU 34, MOST 24
Saturday, September 26th, 2026
Week 5Boston College vs
SMU		SMU 25, BC 16
Saturday, October 3rd, 2026
Week 7Virginia vs
SMU		SMU 23, UVA 13
Saturday, October 17th, 2026
Week 8California vs
SMU		SMU 59, CAL 20
Saturday, October 24th, 2026
Week 9SMU vs
Syracuse		SYR 30, SMU 27
Saturday, October 31st, 2026
Week 10Virginia Tech vs
SMU		SMU 51, VT 28
Friday, November 6th, 2026
Week 11Wake Forest vs
SMU		Saturday, November 14th, 2026
12:00 pm EST
Week 12SMU vs
Notre Dame		Saturday, November 21st, 2026
7:30 pm EST
Week 13SMU vs
Stanford		Saturday, November 28th, 2026
12:00 am EST


2026-27 Louisville Games & Results
WeekMatchupDate & Result
Week 1Louisville vs
Ole Miss		MISS 41, LOU 38
Sunday, September 6th, 2026
Week 2Villanova vs
Louisville		LOU 59, VILL 13
Friday, September 11th, 2026
Week 3SMU vs
Louisville		LOU 41, SMU 31
Saturday, September 19th, 2026
Week 4Wake Forest vs
Louisville		WAKE 30, LOU 27
Saturday, September 26th, 2026
Week 5Louisville vs
NC State		NCSU 31, LOU 28
Saturday, October 3rd, 2026
Week 6Florida State vs
Louisville		LOU 44, FSU 20
Friday, October 9th, 2026
Week 7Louisville vs
Syracuse		LOU 34, SYR 26
Saturday, October 17th, 2026
Week 9Stanford vs
Louisville		LOU 52, STAN 24
Saturday, October 31st, 2026
Week 10Louisville vs
Georgia Tech		LOU 44, GT 17
Saturday, November 7th, 2026
Week 11Louisville vs
North Carolina		Saturday, November 14th, 2026
12:00 am EST
Week 12Pittsburgh vs
Louisville		Saturday, November 21st, 2026
12:00 am EST
Week 13Louisville vs
Kentucky		Saturday, November 28th, 2026
12:00 am EST

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the SMU vs Louisville College Football Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Saturday, September 19th, 2026 at 3:30 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's College Football page, look for the SMU vs Louisville Game.

    Navigate to the sportsbook's College Football page. Next, look for live or upcoming matchups. Select the SMU vs Louisville Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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