The Bulls will play the Cardinals on Thursday, March 19th, 2026. Your timezone's tip off time is 1:30 pm EDT. Check local listings or your nearest streaming app for coverage.
Review our College Basketball Betting guide to learn how to bet this game.
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Table of Contents
- Matchup Stats
- Moneyline Mage
- Best Odds
- Interactive Odds Example
- Prop Bets
- Team Standings
- Futures Odds
- Team Pages
- Other Games Today
Key Matchup Stats
The 2025-26 college basketball postseason has arrived. With tournament action on the docket, USF and Louisville are set to tip-off on Thursday, March 19th, 2026. Here's your chance to partake in March Madness! The end of the regular season has left us with solid trends for each team. Use the following performance insights and stats to handicap what promises to be an exciting matchup.
- SportsBetting3.com Power Rankings - USF wound up with a 99.67 SportsBetting3.com conference power ranking for the 2025-26 college basketball regular season, while Louisville finished with a 96.33 power ranking.
- Away Records - Tournament games are typically played at neutral venues, which means both teams are away from their home courts. USF comes to this matchup with a 9-3 record as an away team, ranking them 2nd in the American Conference for away team wins. Their opponent, Louisville, finished the regular season with a 4-7 record as an away team, ranking them 5th in the ACC Conference for away team wins.
- Conference Win Percentage - USF finished 1st (0.833) in the American Conference, with Louisville ending up 5th (0.611) for their conference win percentage in the 2025 ACC Conference.
- Overall Win Percentage - USF had a 0.758 regular season overall win percentage, with Louisville notching a 0.697 overall win percentage at the end of the 2025-26 regular season.
- Team Records - USF tallied a 25-8 regular season overall record. Meanwhile, Louisville put together a 23-10 standing for 2025-26 college basketball regular season.
Moneyline Mage
Spelling out the winners with humor since the middle ages.
Hocus pocus! USF and Louisville clash in March Madness matchup on Thursday.
USF finished 25-8 overall, Louisville finished 23-10 in regular season play.
15-3 American Conference USF faces 11-7 ACC Louisville in single-elimination game.
The tables below have the best point spread lines, total lines, and moneylines for this matchup. Bet on March Madness games at BetRivers and BetMGM. Review this matchup's prop bets below.
Best Bulls at Cardinals Odds
| Underdog USF | Favorite Louisville |
|---|---|
| Over | Under |
|---|---|
| Underdog USF | Favorite Louisville |
|---|---|
Matchup Odds FAQs
Louisville is a -3.5 -105 point spread favorite at BetMGM, while USF is a +3.5 -115 point spread underdog at BetMGM.
The best over line is 160.5 -110 points at BetMGM, which means you risk $110 to win $100 betting the over. The best under line is 160.5 -110 points at BetMGM, and that means you risk $110 to win $100 betting the under.
Louisville is a -165 moneyline favorite at BetMGM and USF is a +135 moneyline underdog at BetMGM.
College Basketball Odds Example
|
Game |
 BetMGMBet |
|---|---|
USF
Louisville
1:30pm EDT | +3.5 -115-3.5 -105 |
Underdog USF - USF bettors risk $100 to win $86.96 at -115 odds.
A +3.5 USF underdog bet wins if they lose by 3 or fewer, tie, or win outright. Your bet loses if they lose by 4 or more.
Favorite Louisville - Louisville bettors risk $100 to win $95.24 at -105 odds.
A -3.5 Louisville favorite bet wins if they win by 4 or more. Your bet loses if they win by 3 or fewer, tie, or lose outright.
USF at Louisville Prop Bets
Important Note: Some states expressly forbid individual college athlete prop bets. The following wagers may not be available depending on your particular state laws.
| BetMGM Bet |
|
|---|---|
USF
Louisville
First to 5 Points
1:30pm EDT | -105-135Bet |
USF
Louisville
First to 10 Points
1:30pm EDT | -102-135Bet |
USF
Louisville
First to 15 Points
1:30pm EDT | +100-140Bet |
USF
Louisville
Game to Overtime
1:30pm EDT | Yes +800No -3000Bet |
Team Standings
| Team | W-L | Win% | Home | Away | Conf | CGB | Conf% | Strk |
|---|---|---|---|---|---|---|---|---|
| American | ||||||||
| USF | 25-8 | 0.758 | 13-2 | 9-3 | 15-3 | - | 0.833 | W11 |
| ACC | ||||||||
| #23 Louisville | 23-10 | 0.697 | 15-2 | 4-7 | 11-7 | +6 | 0.611 | L1 |
USF & Louisville Futures Odds
Latest College Basketball Championship odds, if available, for each team. Review March Madness odds for other teams and learn how to bet on the college basketball tournament. Also be sure to read Ron Halfback's Final Four write-up.
USF Championship Odds|
Team |
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| OH,US ncaabb Evnum: 1 Odds Pending |
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Team |
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| OH,US ncaabb Evnum: 1 Odds Pending |
USF & Louisville Team Pages
Review each team's futures odds, betting bonuses, current standings and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the USF vs Louisville College Basketball Game
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Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Thursday, March 19th, 2026 at 1:30 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
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Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
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Tap to the sportsbook's College Basketball page, look for the USF vs Louisville Game.
Navigate to the sportsbook's College Basketball page. Next, look for live or upcoming matchups. Select the USF vs Louisville Game.
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Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.
Other March 19, 2026 NCAABB Games
- TCU vs Ohio State - 12:15pm EDT
- Troy vs Nebraska - 12:40pm EDT
- Akron vs Texas Tech - 1:00pm EDT
- Hofstra vs Alabama - 1:00pm EDT
- Wright State vs Virginia - 1:00pm EDT
- Missouri vs Miami (FL) - 1:00pm EDT
- Utah State vs Villanova - 1:00pm EDT
- High Point vs Wisconsin - 1:50pm EDT
- Siena vs Duke - 2:50pm EDT
- McNeese State vs Vanderbilt - 3:15pm EDT
- North Dakota State vs Michigan State - 4:05pm EDT
- Hawaii vs Arkansas - 4:25pm EDT
- VCU vs North Carolina - 6:50pm EDT
- Howard vs Michigan - 7:10pm EDT
- Texas vs BYU - 7:25pm EDT
- Texas A&M vs Saint Mary's (CA) - 7:35pm EDT
- Penn vs Illinois - 9:25pm EDT
- Saint Louis vs Georgia - 9:45pm EDT
- Kennesaw State vs Gonzaga - 10:00pm EDT
- Idaho vs Houston - 10:10pm EDT