Detroit Red Wings vs Buffalo Sabres Odds

The Red Wings will play the Sabres on Wednesday, October 22nd, 2025. Your timezone's face off time is 7:38 pm EDT. Check local listings or your nearest streaming app for coverage.

Learn more about NHL Betting with our handy tutorial and guide. We explain money line, total and puck line bets. Plus, a great discussion about exotic bets like NHL parlays and props.


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Table of Contents

Key Matchup Stats

The 2025-26 NHL regular season is off the ground for the Detroit Red Wings and Buffalo Sabres. Let's review some key performance data in time for the puck drop at center circle. Though it's still early, keep tabs on the following stats as the season progresses.

  • SportsBetting3.com Power Rankings - The Detroit Red Wings have started the 2025-26 regular season with a 98.67 power ranking. The Buffalo Sabres currently posses a 92.33 power ranking as the season gets underway.
  • Away Detroit Red Wings - The Detroit Red Wings have a 1-0-0 record as an away team, ranking them 3rd in the league so far for away team wins. The Detroit Red Wings currently rank 5th for away team losses.
  • Home Buffalo Sabres - The Buffalo Sabres have begun 2025-26 regular season with a 2-2-0 record as a home team. That standing puts them 3rd in the league for home team wins, while they also sit 3rd for home team losses.
  • Goals Scored - At this early stage in the regular season, the Detroit Red Wings rank 7th (20), with the Buffalo Sabres ranking 12th (15) in the league for goals scored.
  • Goals Against - As for goals scored against each team, the Detroit Red Wings stand 14th (14), while the Buffalo Sabres rank 10th (18) so far in the NHL 2025-26 regular season.
  • Team Records - The Detroit Red Wings have a 5-1-0 record, with the Buffalo Sabres owning a 2-4-0 record in the first weeks of the regular season.

Moneyline Mage

Spelling out the winners with humor since the middle ages.

Moneyline Mage
Moneyline Mage

Hear ye, hear ye! The 2025-26 NHL season is underway...with the Detroit Red Wings soaring high at 5-1-0...while the Buffalo Sabres are struggling at 2-4-0...

The Red Wings have lit the lamp 20 times already...showing off their offensive firepower...meanwhile, the Sabres have scored 15 goals...but they are hungry for more...

As the Red Wings travel to Buffalo on Wednesday, October 22nd...be sure to review the odds before the puck drops...check out our hockey betting sportsbooks for the latest predictions...and look at the prop bets available below for some added excitement...

Whether you're a seasoned bettor or new to hockey betting...learn how to bet on hockey at SportsBetting3.com...and witness the magic unfold on the ice...may the best team prevail!

Best Red Wings at Sabres Odds


Best Moneyline Betting Odds
Underdog

Detroit Red Wings
Favorite

Buffalo Sabres
The Buffalo Sabres are the -115 moneyline favorite. Risk $115 to win $100 on the Buffalo Sabres at BetMGM. The Detroit Red Wings are the -105 underdog at BetMGM. Risk $105 to win $100 on the Detroit Red Wings. Learn more about how to bet on money lines.

Best Total Betting Odds
OverUnder
BetMGM has the best over line of 6 goals. Risk $115 to win $100. BetMGM has the best under line of 6 goals. Risk $105 to win $100. Our tutorial explains more about total bets.

Best Puck Line Betting Odds
Underdog

Detroit Red Wings
Favorite

Buffalo Sabres
The Buffalo Sabres have a -1.5 +200 puck line at BetMGM OH. They are the puck line favorite in this matchup. The Detroit Red Wings have a +1.5 -250 puck line at BetMGM OH. The Detroit Red Wings are the puck line underdogs. Review how to bet on a point spread with our text and video tutorials.

Matchup Odds FAQs

What is the moneyline for the Detroit Red Wings vs Buffalo Sabres NHL game on Wednesday, October 22nd, 2025?

The Buffalo Sabres are the -115 moneyline favorite at BetMGM and the Detroit Red Wings are the -105 moneyline underdog at BetMGM.

What is the over-under total line for the Detroit Red Wings vs Buffalo Sabres NHL game on Wednesday, October 22nd, 2025?

The best over line is 6 -115 goals at BetMGM, which means you risk $115 to win $100 betting the over. The best under line is 6 -105 goals at BetMGM, and that means you risk $105 to win $100 betting the under.

What is the puck line for the Detroit Red Wings vs Buffalo Sabres NHL game on Wednesday, October 22nd, 2025?

The Buffalo Sabres are -1.5 +200 puck line favorites at BetMGM, while the Detroit Red Wings are +1.5 -250 puck line underdogs at BetMGM.

NHL Odds Example

NHL Odds and Outcomes Explained

Game
BetMGM Sports Betting BetMGM
Bet
Red Wings
Sabres
10/22/25 7:38pm EDT
-105-115
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Possible Moneyline Outcomes
  • Detroit Red Wings bettors risk $100 to win $95.24 at -105 odds. The implied probability for Detroit Red Wings is 51.22%.
  • Buffalo Sabres bettors risk $100 to win $86.96 at -115 odds. The implied probability for Buffalo Sabres is 53.49%.

Detroit Red Wings at Buffalo Sabres Prop Bets

NHL Prop Bets
+ Displays more odds
BetMGM Sports Betting BetMGM
Bet
Red Wings
Sabres
Both Teams Score 2+ Goals
10/22/25 7:38pm EDT
Yes -185No +135Bet
Sabres
Total Goals
DET at BUF
10/22/25 7:38pm EDT
3 o -1253 u -110Bet
Red Wings
Total Goals
DET at BUF
10/22/25 7:38pm EDT
3 o -1153 u -120Bet
Alex DeBrincat
To Score 3 Goals
DET at BUF
10/22/25 7:38pm EDT
Yes +6600Bet
BetMGM Sports Betting BetMGM
Dylan Larkin
To Score 3 Goals
DET at BUF
10/22/25 7:38pm EDT
Yes +6600Bet
Tage Thompson
To Score 3 Goals
DET at BUF
10/22/25 7:38pm EDT
Yes +5500Bet

Team Standings

2025-2026 NHL Regular Season Standings - Detroit Red Wings, Buffalo Sabres
Team GP W L OTL wPct Pts ROW GF GA Diff Home Away SO L10 Strk
Detroit Red Wings75200.7141052218+4.04-1-01-1-00-05-2-0L1
Buffalo Sabres73400.429631920-1.03-2-00-2-00-03-4-0W1

Detroit Red Wings & Buffalo Sabres Futures Odds

Latest Stanley Cup odds, if available, for each team. Review odds for other teams and learn how Stanley Cup betting works. See past Championship results and learn how to bet NHL teasers, props and parlays.

Detroit Red Wings Stanley Cup Odds
2025-26 Detroit Red Wings Stanley Cup Odds

Team
BetMGM Sports Betting BetMGM
Red Wings
+6000
Bet
Buffalo Sabres Stanley Cup Odds
2025-26 Buffalo Sabres Stanley Cup Odds

Team
BetMGM Sports Betting BetMGM
Sabres
+10000
Bet

Detroit Red Wings & Buffalo Sabres Team Pages

Review each team's season point total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Detroit Red Wings vs Buffalo Sabres NHL Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Wednesday, October 22nd, 2025 at 7:38 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's NHL page, look for the Detroit Red Wings vs Buffalo Sabres Game.

    Navigate to the sportsbook's NHL page. Next, look for live or upcoming matchups. Select the Detroit Red Wings vs Buffalo Sabres Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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