San Francisco Giants vs Cincinnati Reds Odds

The Giants will play the Reds on Thursday, April 16th, 2026. Your timezone's first pitch time is 12:40 pm EDT. Check local listings or your nearest streaming app for coverage.

Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.


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Table of Contents

Key Matchup Stats

  • SportsBetting3.com Power Rankings - The San Francisco Giants have a 86.00 power ranking. The power ranking for the Cincinnati Reds is 92.33.
  • Visiting San Francisco Giants - The San Francisco Giants have a 3-5 record as a visiting team, ranking them 5th Overall for visiting team wins.
  • Home Cincinnati Reds - The Cincinnati Reds have a 6-5 record as a home team. They rank 3rd for home team wins in the Overall standings.
  • Runs Scored - The San Francisco Giants currently stand 25th (55) Overall, with the Cincinnati Reds ranking 22nd (64) for runs scored.
  • Runs Allowed - The San Francisco Giants are 8th (82) Overall for runs allowed. The Cincinnati Reds stand 13th (74) for runs allowed.
  • Team Streaks - The San Francisco Giants have lost their last 4 games. Meanwhile, the Cincinnati Reds have won their last 2 games.
  • Team Records - The San Francisco Giants have a 6-12 Overall record (7.5 GB National West Division), with the Cincinnati Reds possessing a 11-7 Overall standing (0.0 GB National Central Division).

Captain Shady Lines

A broken compass is right at least twice a day.

Captain Shady Lines
Captain Shady Lines

Avast ye scallywags! The Giants face the Reds with a pitiful record... (walking the plank).

San Francisco be playin' like bilge rats, winnin' only 33.3% of games... (shiver me timbers).

Cincinnati be holdin' strong with a 61.1% win rate... (blow me down).

If ye be feelin' lucky, head to SportsBetting3.com and bet on this game... (yo ho ho).

Review the odds below, but beware, the Giants may be doomed to Davy Jones' locker!

Best Giants at Reds Odds


Best Moneyline Betting Odds
Underdog

San Francisco Giants
Favorite

Cincinnati Reds
The Cincinnati Reds are the -125 moneyline favorite. Risk $125 to win $100 on the Cincinnati Reds at BetMGM. The San Francisco Giants are the +105 underdog at BetMGM. Risk $100 to win $105 on the San Francisco Giants. Learn more about how to bet on money lines.

Best Total Betting Odds
OverUnder
BetMGM has the best over line of 8 runs. Risk $115 to win $100. BetMGM has the best under line of 8 runs. Risk $105 to win $100. Our tutorial explains more about total bets.

Best Run Line Betting Odds
Underdog

Cincinnati Reds
Favorite

San Francisco Giants
The San Francisco Giants have a -1.5 +170 run line at BetMGM OH. They are the run line favorite in this matchup. The Cincinnati Reds have a +1.5 -210 run line at BetMGM OH. The Cincinnati Reds are the run line underdogs. Review how to bet on a point spread with our text and video tutorials.

Matchup Odds FAQs

What is the moneyline for the San Francisco Giants vs Cincinnati Reds MLB game on Thursday, April 16th, 2026?

The Cincinnati Reds are the -125 moneyline favorite at BetMGM and the San Francisco Giants are the +105 moneyline underdog at BetMGM.

What is the over-under total line for the San Francisco Giants vs Cincinnati Reds MLB game on Thursday, April 16th, 2026?

The best over line is 8 -115 runs at BetMGM, which means you risk $115 to win $100 betting the over. The best under line is 8 -105 runs at BetMGM, and that means you risk $105 to win $100 betting the under.

What is the run line for the San Francisco Giants vs Cincinnati Reds MLB game on Thursday, April 16th, 2026?

The San Francisco Giants are -1.5 +170 run line favorites at BetMGM, while the Cincinnati Reds are +1.5 -210 run line underdogs at BetMGM.

MLB Odds Example

MLB Odds and Outcomes Explained

Game
BetMGM Sports Betting BetMGM
Bet
Giants
Reds
4/16/26 12:40pm EDT
+105-125
Bet $100 at BetMGM Ohio
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Possible Moneyline Outcomes
  • San Francisco Giants bettors risk $100 to win $105 at +105 odds. The implied probability for San Francisco Giants is 48.78%.
  • Cincinnati Reds bettors risk $100 to win $80 at -125 odds. The implied probability for Cincinnati Reds is 55.56%.

San Francisco Giants at Cincinnati Reds Prop Bets

MLB Prop Bets
+ Displays more odds
BetMGM Sports Betting BetMGM
Bet
Giants
Reds
First Team to Score
4/16/26 12:40pm EDT
-145+110Bet
Giants
Reds
Tie
1st Inning Winner
4/16/26 12:40pm EDT
+325+310-150Bet
Giants
Reds
Tie
First 3 Innings Winner
4/16/26 12:40pm EDT
+160+135+260Bet
Giants
Reds
To Extra Innings
4/16/26 12:40pm EDT
Yes +725No -1200Bet
BetMGM Sports Betting BetMGM
Giants
Reds
1st Team to Score Will Win
4/16/26 12:40pm EDT
Yes -250No +190Bet
Reds
Total Runs
SFO at CIN
4/16/26 12:40pm EDT
3.5 o -1503.5 u +115Bet
Giants
Total Runs
SFO at CIN
4/16/26 12:40pm EDT
3.5 o -1403.5 u +105Bet

San Francisco Giants & Cincinnati Reds Futures Odds

Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.

San Francisco Giants World Series Odds
2026 San Francisco Giants World Series Odds

Team
BetMGM Sports Betting BetMGM
Giants
+10000
Bet
Cincinnati Reds World Series Odds
2026 Cincinnati Reds World Series Odds

Team
BetMGM Sports Betting BetMGM
Reds
+4000
Bet

San Francisco Giants & Cincinnati Reds Team Pages

Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Standings

2026 MLB Regular Season Standings - San Francisco Giants, Cincinnati Reds
Team W L Pct GB Home Away RS RA Diff Strk L10
Cincinnati Reds1680.667+0.56-610-29693+3W58-2
San Francisco Giants10130.435+6.04-76-67897-19W15-5

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the San Francisco Giants vs Cincinnati Reds MLB Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Thursday, April 16th, 2026 at 12:40 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's MLB page, look for the San Francisco Giants vs Cincinnati Reds Game.

    Navigate to the sportsbook's MLB page. Next, look for live or upcoming matchups. Select the San Francisco Giants vs Cincinnati Reds Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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