The Padres will play the Astros on Sunday, April 20th, 2025. Your timezone's first pitch time is 7:10 pm EDT. Check local listings or your nearest streaming app for coverage.
Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.
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Table of Contents
- Matchup Stats
- Captain Shady Lines
- Best Odds
- Interactive Odds Example
- Prop Bets
- Team Futures Odds
- Team Pages
- Team Standings
- Other Games Today
Key Matchup Stats
- SportsBetting3.com Power Rankings - The San Diego Padres have a 98.00 power ranking. The power ranking for the Houston Astros is 92.33.
- Visiting San Diego Padres - The San Diego Padres have a 3-4 record as a visiting team, ranking them 7th Overall for visiting team wins.
- Home Houston Astros - The Houston Astros have a 5-5 record as a home team. They rank 7th for home team wins in the Overall standings.
- Runs Scored - The San Diego Padres currently stand 9th (92) Overall, with the Houston Astros ranking 20th (72) for runs scored.
- Runs Allowed - The San Diego Padres are 18th (57) Overall for runs allowed. The Houston Astros stand 15th (74) for runs allowed.
- Team Streaks - The San Diego Padres lost their last game. Meanwhile, the Houston Astros won their last game.
- Team Records - The San Diego Padres have a 15-5 Overall record (0.0 GB National West Division), with the Houston Astros possessing a 9-10 Overall standing (2.5 GB American West Division).
Captain Shady Lines
A broken compass is right at least twice a day.
Arrgh, ye scallywags! The Padres be plundering the Astros on Sunday!
San Diego sets sail with a record that be striking fear in Houston...
With a 0.750 win percentage, the Padres be leavin' opponents walkin' the plank...
SportsBetting3.com be where ye can bet on this game, so review the odds below!
Best Padres at Astros Odds
| Underdog San Diego Padres | Favorite Houston Astros |
|---|---|
| Over | Under |
|---|---|
| Underdog Houston Astros | Favorite San Diego Padres |
|---|---|
Matchup Odds FAQs
The Houston Astros are the -115 moneyline favorite at BetMGM and the San Diego Padres are the -105 moneyline underdog at BetMGM.
The best over line is 7.5 +100 runs at BetMGM, which means you risk $100 to win $100 betting the over. The best under line is 7.5 -120 runs at BetMGM, and that means you risk $120 to win $100 betting the under.
The San Diego Padres are -1.5 +165 run line favorites at BetMGM, while the Houston Astros are +1.5 -200 run line underdogs at BetMGM.
MLB Odds Example
|
Game |
 BetMGMBet |
|---|---|
Padres
Astros
4/20/25 7:10pm EDT | -105-115 |
- San Diego Padres bettors risk $100 to win $95.24 at -105 odds. The implied probability for San Diego Padres is 51.22%.
- Houston Astros bettors risk $100 to win $86.96 at -115 odds. The implied probability for Houston Astros is 53.49%.
San Diego Padres at Houston Astros Prop Bets
| BetMGM Bet |
|
|---|---|
Padres
Astros
First Team to Score
4/20/25 7:10pm EDT | -155+118Bet |
Padres
Astros
Tie
1st Inning Winner
4/20/25 7:10pm EDT | +320+350-160Bet |
Padres
Astros
Tie
First 3 Innings Winner
4/20/25 7:10pm EDT | +145+160+240Bet |
Padres
Astros
To Extra Innings
4/20/25 7:10pm EDT | Yes +700No -1100Bet |
| BetMGM | |
Padres
Astros
1st Team to Score Will Win
4/20/25 7:10pm EDT | Yes -250No +190Bet |
Astros
Total Runs
SDG at HOU 4/20/25 7:10pm EDT | 3.5 o -1153.5 u -115Bet |
Padres
Total Runs
SDG at HOU 4/20/25 7:10pm EDT | 3.5 o -1183.5 u -110Bet |
Dylan Cease
Strikeouts Thrown
SDG at HOU 4/20/25 7:10pm EDT | 5.5 o -1305.5 u +100Bet |
| BetMGM | |
Framber Valdez
Strikeouts Thrown
SDG at HOU 4/20/25 7:10pm EDT | 5.5 o +1155.5 u -155Bet |
San Diego Padres & Houston Astros Futures Odds
Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.
San Diego Padres World Series Odds|
Team | BetMGM |
|---|---|
| Padres | +2000 Bet |
|
Team | BetMGM |
|---|---|
| Astros | +2200 Bet |
San Diego Padres & Houston Astros Team Pages
Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:
Team Standings
| Team | W | L | Pct | GB | Home | Away | RS | RA | Diff | Strk | L10 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| San Diego Padres | 17 | 11 | 0.607 | +2.5 | 12-4 | 5-7 | 106 | 83 | +23 | L4 | 3-7 |
| Houston Astros | 15 | 13 | 0.536 | +4.5 | 10-6 | 5-7 | 107 | 93 | +14 | W2 | 7-3 |
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the San Diego Padres vs Houston Astros MLB Game
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Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Sunday, April 20th, 2025 at 7:10 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
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Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
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Tap to the sportsbook's MLB page, look for the San Diego Padres vs Houston Astros Game.
Navigate to the sportsbook's MLB page. Next, look for live or upcoming matchups. Select the San Diego Padres vs Houston Astros Game.
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Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.
Other April 20, 2025 MLB Games
- Minnesota Twins vs Atlanta Braves - 4/20/25 1:35pm EDT
- Cincinnati Reds vs Baltimore Orioles - 4/20/25 1:35pm EDT
- Chicago White Sox vs Boston Red Sox - 4/20/25 1:35pm EDT
- Miami Marlins vs Philadelphia Phillies - 4/20/25 1:35pm EDT
- Cleveland Guardians vs Pittsburgh Pirates - 4/20/25 1:35pm EDT
- Seattle Mariners vs Toronto Blue Jays - 4/20/25 1:37pm EDT
- New York Yankees vs Tampa Bay Rays - 4/20/25 1:40pm EDT
- St. Louis Cardinals vs New York Mets - 4/20/25 1:40pm EDT
- Kansas City Royals vs Detroit Tigers - 4/20/25 1:40pm EDT
- Oakland Athletics vs Milwaukee Brewers - 4/20/25 2:10pm EDT
- Arizona Diamondbacks vs Chicago Cubs - 4/20/25 2:20pm EDT
- Los Angeles Dodgers vs Texas Rangers - 4/20/25 2:35pm EDT
- Washington Nationals vs Colorado Rockies - 4/20/25 3:10pm EDT
- San Francisco Giants vs Los Angeles Angels - 4/20/25 4:07pm EDT
- Washington Nationals vs Colorado Rockies - 4/20/25 8:10pm EDT