Arizona Diamondbacks vs San Diego Padres Odds

The Diamondbacks will play the Padres on Sunday, September 28th, 2025. Your timezone's first pitch time is 3:10 pm EDT. Check local listings or your nearest streaming app for coverage.

Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.


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Table of Contents

Best Diamondbacks at Padres Odds


Best Moneyline Betting Odds
Underdog

Arizona Diamondbacks
Favorite

San Diego Padres
The San Diego Padres are the -125 moneyline favorite. Risk $125 to win $100 on the San Diego Padres at BetMGM. The Arizona Diamondbacks are the +105 underdog at BetMGM. Risk $100 to win $105 on the Arizona Diamondbacks. Learn more about how to bet on money lines.

Best Total Betting Odds
OverUnder
BetMGM has the best over line of 8 runs. Risk $105 to win $100. BetMGM has the best under line of 8 runs. Risk $115 to win $100. Our tutorial explains more about total bets.

Best Run Line Betting Odds
Underdog

Arizona Diamondbacks
Favorite

San Diego Padres
The San Diego Padres have a -1.5 +170 run line at BetMGM OH. They are the run line favorite in this matchup. The Arizona Diamondbacks have a +1.5 -210 run line at BetMGM OH. The Arizona Diamondbacks are the run line underdogs. Review how to bet on a point spread with our text and video tutorials.

Matchup Odds FAQs

What is the moneyline for the Arizona Diamondbacks vs San Diego Padres MLB game on Sunday, September 28th, 2025?

The San Diego Padres are the -125 moneyline favorite at BetMGM and the Arizona Diamondbacks are the +105 moneyline underdog at BetMGM.

What is the over-under total line for the Arizona Diamondbacks vs San Diego Padres MLB game on Sunday, September 28th, 2025?

The best over line is 8 -105 runs at BetMGM, which means you risk $105 to win $100 betting the over. The best under line is 8 -115 runs at BetMGM, and that means you risk $115 to win $100 betting the under.

What is the run line for the Arizona Diamondbacks vs San Diego Padres MLB game on Sunday, September 28th, 2025?

The San Diego Padres are -1.5 +170 run line favorites at BetMGM, while the Arizona Diamondbacks are +1.5 -210 run line underdogs at BetMGM.

MLB Odds Example

MLB Odds and Outcomes Explained

Game
BetMGM Sports Betting BetMGM
Bet
Diamondbacks
Padres
9/28/25 3:10pm EDT
+105-125
Bet $100 at BetMGM Ohio
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Possible Moneyline Outcomes
  • Arizona Diamondbacks bettors risk $100 to win $105 at +105 odds. The implied probability for Arizona Diamondbacks is 48.78%.
  • San Diego Padres bettors risk $100 to win $80 at -125 odds. The implied probability for San Diego Padres is 55.56%.

Arizona Diamondbacks at San Diego Padres Prop Bets

MLB Prop Bets
+ Displays more odds
BetMGM Sports Betting BetMGM
Bet
Diamondbacks
Padres
First Team to Score
9/28/25 3:10pm EDT
-150+118Bet
Diamondbacks
Padres
Tie
1st Inning Winner
9/28/25 3:10pm EDT
+300+300-140Bet
Diamondbacks
Padres
Tie
First 3 Innings Winner
9/28/25 3:10pm EDT
+150+140+270Bet
Diamondbacks
Padres
To Extra Innings
9/28/25 3:10pm EDT
Yes +725No -1200Bet
BetMGM Sports Betting BetMGM
Diamondbacks
Padres
1st Team to Score Will Win
9/28/25 3:10pm EDT
Yes -250No +190Bet
Diamondbacks
Total Runs
ARI at SDG
9/28/25 3:10pm EDT
3.5 o -1303.5 u +100Bet
Padres
Total Runs
ARI at SDG
9/28/25 3:10pm EDT
3.5 o -1403.5 u +105Bet
Brandon Pfaadt
Strikeouts Thrown
ARI at SDG
9/28/25 3:10pm EDT
3.5 o -1053.5 u -125Bet
BetMGM Sports Betting BetMGM
JP Sears
Strikeouts Thrown
ARI at SDG
9/28/25 3:10pm EDT
3.5 o +1053.5 u -140Bet

Arizona Diamondbacks & San Diego Padres Futures Odds

Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.

Arizona Diamondbacks World Series Odds
2026 Arizona Diamondbacks World Series Odds

Team
BetMGM Sports Betting BetMGM
Diamondbacks
+6000
Bet
San Diego Padres World Series Odds
2026 San Diego Padres World Series Odds

Team
BetMGM Sports Betting BetMGM
Padres
+2000
Bet

Arizona Diamondbacks & San Diego Padres Team Pages

Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Standings

2025 MLB Regular Season Standings - Arizona Diamondbacks, San Diego Padres
Team W L Pct GB Home Away RS RA Diff Strk L10
y - San Diego Padres90720.556+7.052-2938-43702621+81W37-3
e - Arizona Diamondbacks80820.494+17.043-3837-44791785+6L53-7

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Arizona Diamondbacks vs San Diego Padres MLB Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Sunday, September 28th, 2025 at 3:10 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's MLB page, look for the Arizona Diamondbacks vs San Diego Padres Game.

    Navigate to the sportsbook's MLB page. Next, look for live or upcoming matchups. Select the Arizona Diamondbacks vs San Diego Padres Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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