Boston Red Sox vs Tampa Bay Rays Odds

The Red Sox will play the Rays on Sunday, September 21st, 2025. Your timezone's first pitch time is 7:35 pm EDT. Check local listings or your nearest streaming app for coverage.

Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.

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Best Red Sox at Rays Odds

**Best Moneyline Betting Odds**
Underdog Tampa Bay Rays	Favorite Boston Red Sox
+110 BetMGM Bet	-130 BetMGM Bet

The Boston Red Sox are the -130 moneyline favorite. Risk $130 to win $100 on the Boston Red Sox at BetMGM. The Tampa Bay Rays are the +110 underdog at BetMGM. Risk $100 to win $110 on the Tampa Bay Rays. Learn more about how to bet on money lines.

**Best Total Betting Odds**
Over	Under
8 o -105 BetMGM Bet	8 u -115 BetMGM Bet

BetMGM has the best over line of 8 runs. Risk $105 to win $100. BetMGM has the best under line of 8 runs. Risk $115 to win $100. Our tutorial explains more about total bets.

**Best Run Line Betting Odds**
Underdog Tampa Bay Rays	Favorite Boston Red Sox
+1.5 -160 BetMGM Bet	-1.5 +135 BetMGM Bet

The Boston Red Sox have a -1.5 +135 run line at BetMGM OH. They are the run line favorite in this matchup. The Tampa Bay Rays have a +1.5 -160 run line at BetMGM OH. The Tampa Bay Rays are the run line underdogs. Review how to bet on a point spread with our text and video tutorials.

Matchup Odds FAQs

What is the moneyline for the Boston Red Sox vs Tampa Bay Rays MLB game on Sunday, September 21st, 2025?

The Boston Red Sox are the -130 moneyline favorite at BetMGM and the Tampa Bay Rays are the +110 moneyline underdog at BetMGM.

What is the over-under total line for the Boston Red Sox vs Tampa Bay Rays MLB game on Sunday, September 21st, 2025?

The best over line is 8 -105 runs at BetMGM, which means you risk $105 to win $100 betting the over. The best under line is 8 -115 runs at BetMGM, and that means you risk $115 to win $100 betting the under.

What is the run line for the Boston Red Sox vs Tampa Bay Rays MLB game on Sunday, September 21st, 2025?

The Boston Red Sox are -1.5 +135 run line favorites at BetMGM, while the Tampa Bay Rays are +1.5 -160 run line underdogs at BetMGM.

MLB Odds Example

MLB Odds and Outcomes Explained
Game	BetMGM Bet
Red Sox Rays 9/21/25 7:35pm EDT	-130 +110

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Possible Moneyline Outcomes

Tampa Bay Rays bettors risk $100 to win $110 at +110 odds. The implied probability for Tampa Bay Rays is 47.62%.
Boston Red Sox bettors risk $100 to win $76.92 at -130 odds. The implied probability for Boston Red Sox is 56.52%.

Boston Red Sox at Tampa Bay Rays Prop Bets

MLB Prop Bets
+ Displays more odds
	BetMGM Bet
Red Sox Rays First Team to Score 9/21/25 7:35pm EDT	-165 +130 Bet
Red Sox Rays Tie 1st Inning Winner 9/21/25 7:35pm EDT	+275 +325 -140 Bet
Red Sox Rays Tie First 3 Innings Winner 9/21/25 7:35pm EDT	+130 +154 +280 Bet
Red Sox Rays To Extra Innings 9/21/25 7:35pm EDT	Yes +725 No -1200 Bet
	BetMGM
Red Sox Rays 1st Team to Score Will Win 9/21/25 7:35pm EDT	Yes -250 No +190 Bet
Red Sox Total Runs BOS at TAM 9/21/25 7:35pm EDT	4.5 o +110 4.5 u -145 Bet
Rays Total Runs BOS at TAM 9/21/25 7:35pm EDT	3.5 o -115 3.5 u -115 Bet
Connelly Early Strikeouts Thrown BOS at TAM 9/21/25 7:35pm EDT	5.5 o -160 5.5 u +120 Bet
	BetMGM
Joe Boyle Strikeouts Thrown BOS at TAM 9/21/25 7:35pm EDT	4.5 o -130 4.5 u +100 Bet

Boston Red Sox & Tampa Bay Rays Futures Odds

Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.

Boston Red Sox World Series Odds

No World Series TM Boston Red Sox YR: futures available

Tampa Bay Rays World Series Odds

No World Series TM Tampa Bay Rays YR: futures available

Boston Red Sox & Tampa Bay Rays Team Pages

Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Standings

2025 MLB Regular Season Standings - Boston Red Sox, Tampa Bay Rays
Team	W	L	Pct	GB	Home	Away	RS	RA	Diff	Strk	L10
y - Boston Red Sox	89	73	0.549	+8.0	48-33	41-40	786	676	+110	W1	6-4
e - Tampa Bay Rays	77	85	0.475	+20.0	41-40	36-45	714	683	+31	L4	3-7

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Boston Red Sox vs Tampa Bay Rays MLB Game

Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Sunday, September 21st, 2025 at 7:35 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
Tap to the sportsbook's MLB page, look for the Boston Red Sox vs Tampa Bay Rays Game.
Navigate to the sportsbook's MLB page. Next, look for live or upcoming matchups. Select the Boston Red Sox vs Tampa Bay Rays Game.
Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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