The Cubs will play the Marlins on Wednesday, May 21st, 2025. Your timezone's first pitch time is 1:10 pm EDT. Check local listings or your nearest streaming app for coverage.
Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.
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Table of Contents
- Matchup Stats
- Captain Shady Lines
- Best Odds
- Interactive Odds Example
- Prop Bets
- Team Futures Odds
- Team Pages
- Team Standings
- Other Games Today
Key Matchup Stats
- SportsBetting3.com Power Rankings - The Chicago Cubs have a 98.00 power ranking. The power ranking for the Miami Marlins is 86.33.
- Visiting Chicago Cubs - The Chicago Cubs have a 14-10 record as a visiting team, ranking them 1st Overall for visiting team wins.
- Home Miami Marlins - The Miami Marlins have a 13-14 record as a home team. They rank 5th for home team wins in the Overall standings.
- Runs Scored - The Chicago Cubs currently stand 1st (291) Overall, with the Miami Marlins ranking 18th (196) for runs scored.
- Runs Allowed - The Chicago Cubs are 11th (209) Overall for runs allowed. The Miami Marlins stand 2nd (274) for runs allowed.
- Team Streaks - The Chicago Cubs won their last game. Meanwhile, the Miami Marlins lost their last game.
- Team Records - The Chicago Cubs have a 29-20 Overall record (0.0 GB National Central Division), with the Miami Marlins possessing a 19-28 Overall standing (10.5 GB National East Division).
Captain Shady Lines
A broken compass is right at least twice a day.
Avast ye scallywags! The Cubs be takin' on the Marlins in Miami...
Chicago's got a strong record, while the Marlins be flounderin' like landlubbers...
If ye be lookin' to make some gold doubloons, bet on this game at SportsBetting3.com... (review the odds below) The Cubs be the favorites to plunder a victory on the high seas...
Best Cubs at Marlins Odds
| Underdog Miami Marlins | Favorite Chicago Cubs |
|---|---|
| Over | Under |
|---|---|
| Underdog Miami Marlins | Favorite Chicago Cubs |
|---|---|
Matchup Odds FAQs
The Chicago Cubs are the -145 moneyline favorite at BetMGM and the Miami Marlins are the +120 moneyline underdog at BetMGM.
The best over line is 9 +100 runs at BetMGM, which means you risk $100 to win $100 betting the over. The best under line is 9 -120 runs at BetMGM, and that means you risk $120 to win $100 betting the under.
The Chicago Cubs are -1.5 +115 run line favorites at BetMGM, while the Miami Marlins are +1.5 -140 run line underdogs at BetMGM.
MLB Odds Example
|
Game |
 BetMGMBet |
|---|---|
Cubs
Marlins
5/21/25 1:10pm EDT | -145+120 |
- Miami Marlins bettors risk $100 to win $120 at +120 odds. The implied probability for Miami Marlins is 45.45%.
- Chicago Cubs bettors risk $100 to win $68.97 at -145 odds. The implied probability for Chicago Cubs is 59.18%.
Chicago Cubs at Miami Marlins Prop Bets
| BetMGM Bet |
|
|---|---|
Cubs
Marlins
First Team to Score
5/21/25 1:10pm EDT | -190+145Bet |
Cubs
Marlins
Tie
1st Inning Winner
5/21/25 1:10pm EDT | +240+320-120Bet |
Cubs
Marlins
Tie
First 3 Innings Winner
5/21/25 1:10pm EDT | +115+165+320Bet |
Cubs
Marlins
To Extra Innings
5/21/25 1:10pm EDT | Yes +775No -1400Bet |
| BetMGM | |
Cubs
Marlins
1st Team to Score Will Win
5/21/25 1:10pm EDT | Yes -250No +190Bet |
Cubs
Total Runs
CUB at MIA 5/21/25 1:10pm EDT | 4.5 o -1184.5 u -110Bet |
Marlins
Total Runs
CUB at MIA 5/21/25 1:10pm EDT | 3.5 o -1403.5 u +105Bet |
Cade Horton
Strikeouts Thrown
CUB at MIA 5/21/25 1:10pm EDT | 4.5 o -1104.5 u -118Bet |
| BetMGM | |
Max Meyer
Strikeouts Thrown
CUB at MIA 5/21/25 1:10pm EDT | 5.5 o -1155.5 u -115Bet |
Chicago Cubs & Miami Marlins Futures Odds
Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.
Chicago Cubs World Series Odds|
Team | BetMGM |
|---|---|
| Cubs | +1300 Bet |
|
Team | BetMGM |
|---|---|
| Marlins | +50000 Bet |
Chicago Cubs & Miami Marlins Team Pages
Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:
Team Standings
| Team | W | L | Pct | GB | Home | Away | RS | RA | Diff | Strk | L10 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Chicago Cubs | 33 | 21 | 0.611 | +2.0 | 16-10 | 17-11 | 324 | 231 | +93 | W2 | 8-2 |
| Miami Marlins | 21 | 31 | 0.404 | +13.0 | 13-15 | 8-16 | 213 | 289 | -76 | L1 | 5-5 |
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the Chicago Cubs vs Miami Marlins MLB Game
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Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Wednesday, May 21st, 2025 at 1:10 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
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Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
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Tap to the sportsbook's MLB page, look for the Chicago Cubs vs Miami Marlins Game.
Navigate to the sportsbook's MLB page. Next, look for live or upcoming matchups. Select the Chicago Cubs vs Miami Marlins Game.
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Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.
Other May 21, 2025 MLB Games
- Cincinnati Reds vs Pittsburgh Pirates
- Baltimore Orioles vs Milwaukee Brewers
- Houston Astros vs Tampa Bay Rays
- Detroit Tigers vs St. Louis Cardinals
- Seattle Mariners vs Chicago White Sox
- Cleveland Guardians vs Minnesota Twins
- Kansas City Royals vs San Francisco Giants
- New York Mets vs Boston Red Sox
- Atlanta Braves vs Washington Nationals
- Texas Rangers vs New York Yankees
- San Diego Padres vs Toronto Blue Jays
- Cleveland Guardians vs Minnesota Twins
- Philadelphia Phillies vs Colorado Rockies
- Los Angeles Angels vs Oakland Athletics
- Arizona Diamondbacks vs Los Angeles Dodgers