Chicago Cubs vs San Diego Padres Odds

The Cubs will play the Padres on Wednesday, April 29th, 2026. Your timezone's first pitch time is 4:10 pm EDT. Check local listings or your nearest streaming app for coverage.

Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.


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Table of Contents

Key Matchup Stats

  • SportsBetting3.com Power Rankings - The Chicago Cubs have a 99.00 power ranking. The power ranking for the San Diego Padres is 97.33.
  • Visiting Chicago Cubs - The Chicago Cubs have a 5-4 record as a visiting team, ranking them 5th Overall for visiting team wins.
  • Home San Diego Padres - The San Diego Padres have a 9-4 record as a home team. They rank 1st for home team wins in the Overall standings.
  • Runs Scored - The Chicago Cubs currently stand 4th (124) Overall, with the San Diego Padres ranking 16th (97) for runs scored.
  • Runs Allowed - The Chicago Cubs are 19th (87) Overall for runs allowed. The San Diego Padres stand 23rd (79) for runs allowed.
  • Team Streaks - The Chicago Cubs have won their last 7 games. Meanwhile, the San Diego Padres have won their last 3 games.
  • Team Records - The Chicago Cubs have a 14-9 Overall record (1.5 GB National Central Division), with the San Diego Padres possessing a 16-7 Overall standing (0.0 GB National West Division).

Captain Shady Lines

A broken compass is right at least twice a day.

Captain Shady Lines
Captain Shady Lines

Avast ye Cubs fans! The lads be takin' on the Padres in San Diego...

Chicago be comin' in with a solid record, but the Padres be on fire...

Ye best head over to SportsBetting3.com, bet on this game, and review the odds below!

Best Cubs at Padres Odds


Best Moneyline Betting Odds
Underdog

Chicago Cubs
Favorite

San Diego Padres
The San Diego Padres are the -115 moneyline favorite. Risk $115 to win $100 on the San Diego Padres at BetMGM. The Chicago Cubs are the -105 underdog at BetMGM. Risk $105 to win $100 on the Chicago Cubs. Learn more about how to bet on money lines.

Best Total Betting Odds
OverUnder
BetMGM has the best over line of 9 runs. Risk $100 to win $100. BetMGM has the best under line of 9 runs. Risk $120 to win $100. Our tutorial explains more about total bets.

Best Run Line Betting Odds
Underdog

San Diego Padres
Favorite

Chicago Cubs
The Chicago Cubs have a -1.5 +155 run line at BetMGM OH. They are the run line favorite in this matchup. The San Diego Padres have a +1.5 -190 run line at BetMGM OH. The San Diego Padres are the run line underdogs. Review how to bet on a point spread with our text and video tutorials.

Matchup Odds FAQs

What is the moneyline for the Chicago Cubs vs San Diego Padres MLB game on Wednesday, April 29th, 2026?

The San Diego Padres are the -115 moneyline favorite at BetMGM and the Chicago Cubs are the -105 moneyline underdog at BetMGM.

What is the over-under total line for the Chicago Cubs vs San Diego Padres MLB game on Wednesday, April 29th, 2026?

The best over line is 9 +100 runs at BetMGM, which means you risk $100 to win $100 betting the over. The best under line is 9 -120 runs at BetMGM, and that means you risk $120 to win $100 betting the under.

What is the run line for the Chicago Cubs vs San Diego Padres MLB game on Wednesday, April 29th, 2026?

The Chicago Cubs are -1.5 +155 run line favorites at BetMGM, while the San Diego Padres are +1.5 -190 run line underdogs at BetMGM.

MLB Odds Example

MLB Odds and Outcomes Explained

Game
BetMGM Sports Betting BetMGM
Bet
Cubs
Padres
4/29/26 4:10pm EDT
-105-115
Bet $100 at BetMGM Ohio
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Possible Moneyline Outcomes
  • Chicago Cubs bettors risk $100 to win $95.24 at -105 odds. The implied probability for Chicago Cubs is 51.22%.
  • San Diego Padres bettors risk $100 to win $86.96 at -115 odds. The implied probability for San Diego Padres is 53.49%.

Chicago Cubs at San Diego Padres Prop Bets

MLB Prop Bets
+ Displays more odds
BetMGM Sports Betting BetMGM
Bet
Cubs
Padres
First Team to Score
4/29/26 4:10pm EDT
-165+130Bet
Cubs
Padres
Tie
1st Inning Winner
4/29/26 4:10pm EDT
+260+290-120Bet
Cubs
Padres
Tie
First 3 Innings Winner
4/29/26 4:10pm EDT
+125+145+320Bet
Cubs
Padres
To Extra Innings
4/29/26 4:10pm EDT
Yes +800No -1400Bet
BetMGM Sports Betting BetMGM
Cubs
Padres
1st Team to Score Will Win
4/29/26 4:10pm EDT
Yes -250No +190Bet
Cubs
Total Runs
CUB at SDG
4/29/26 4:10pm EDT
4.5 o -1024.5 u -130Bet
Padres
Total Runs
CUB at SDG
4/29/26 4:10pm EDT
4.5 o +1054.5 u -140Bet

Chicago Cubs & San Diego Padres Futures Odds

Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.

Chicago Cubs World Series Odds
2026 Chicago Cubs World Series Odds

Team
BetMGM Sports Betting BetMGM
Cubs
+1000
Bet
San Diego Padres World Series Odds
2026 San Diego Padres World Series Odds

Team
BetMGM Sports Betting BetMGM
Padres
+3500
Bet

Chicago Cubs & San Diego Padres Team Pages

Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Standings

2026 MLB Regular Season Standings - Chicago Cubs, San Diego Padres
Team W L Pct GB Home Away RS RA Diff Strk L10
San Diego Padres1670.6960.09-47-39779+18W39-1
Chicago Cubs1490.609+2.09-55-412487+37W78-2

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Chicago Cubs vs San Diego Padres MLB Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Wednesday, April 29th, 2026 at 4:10 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's MLB page, look for the Chicago Cubs vs San Diego Padres Game.

    Navigate to the sportsbook's MLB page. Next, look for live or upcoming matchups. Select the Chicago Cubs vs San Diego Padres Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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