The White Sox will play the Guardians on Thursday, April 10th, 2025. Your timezone's first pitch time is 1:10 pm EDT. Check local listings or your nearest streaming app for coverage.
Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.
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Table of Contents
- Matchup Stats
- Captain Shady Lines
- Best Odds
- Interactive Odds Example
- Prop Bets
- Team Futures Odds
- Team Pages
- Team Standings
- Other Games Today
Key Matchup Stats
- SportsBetting3.com Power Rankings - The Chicago White Sox have a 88.67 power ranking. The power ranking for the Cleveland Guardians is 90.67.
- Visiting Chicago White Sox - The Chicago White Sox have a 0-5 record as a visiting team, ranking them 6th Overall for visiting team wins.
- Home Cleveland Guardians - The Cleveland Guardians have a 2-0 record as a home team. They rank 6th for home team wins in the Overall standings.
- Runs Scored - The Chicago White Sox currently stand 20th (34) Overall, with the Cleveland Guardians ranking 19th (38) for runs scored.
- Runs Allowed - The Chicago White Sox are 17th (41) Overall for runs allowed. The Cleveland Guardians stand 11th (53) for runs allowed.
- Team Streaks - The Chicago White Sox have lost their last 7 games. Meanwhile, the Cleveland Guardians have won their last 2 games.
- Team Records - The Chicago White Sox have a 2-9 Overall record (4.5 GB American Central Division), with the Cleveland Guardians possessing a 5-6 Overall standing (1.5 GB American Central Division).
Captain Shady Lines
A broken compass is right at least twice a day.
Avast ye scallywags! The White Sox be settin' sail for Cleveland on April 10th...
With a dismal record of 2-9, they be lookin' to turn the tide...
But beware, the Guardians be holdin' strong at home with a 5-6 record...
Ye can bet on this game at SportsBetting3.com and review the odds below...
The White Sox be needin' to find their sea legs to avoid walkin' the plank...
With a win percentage of just 0.182, they be in dire need of victory...
The Guardians be ready to defend their home turf, so it be no easy feat...
Don't be a lily-livered landlubber, place yer wagers and watch the battle unfold...
Best White Sox at Guardians Odds
| Underdog Chicago White Sox | Favorite Cleveland Guardians |
|---|---|
| Over | Under |
|---|---|
| Underdog Chicago White Sox | Favorite Cleveland Guardians |
|---|---|
Matchup Odds FAQs
The Cleveland Guardians are the -250 moneyline favorite at BetMGM and the Chicago White Sox are the +200 moneyline underdog at BetMGM.
The best over line is 7 -125 runs at BetMGM, which means you risk $125 to win $100 betting the over. The best under line is 7 +105 runs at BetMGM, and that means you risk $100 to win $105 betting the under.
The Cleveland Guardians are -1.5 -115 run line favorites at BetMGM, while the Chicago White Sox are +1.5 -105 run line underdogs at BetMGM.
MLB Odds Example
|
Game |
 BetMGMBet |
|---|---|
White Sox
Guardians
4/10/25 1:10pm EDT | +200-250 |
- Chicago White Sox bettors risk $100 to win $200 at +200 odds. The implied probability for Chicago White Sox is 33.33%.
- Cleveland Guardians bettors risk $100 to win $40 at -250 odds. The implied probability for Cleveland Guardians is 71.43%.
Chicago White Sox at Cleveland Guardians Prop Bets
| BetMGM Bet |
|
|---|---|
White Sox
Guardians
First Team to Score
4/10/25 1:10pm EDT | +105-135Bet |
White Sox
Guardians
Tie
1st Inning Winner
4/10/25 1:10pm EDT | +450+260-160Bet |
White Sox
Guardians
Tie
First 3 Innings Winner
4/10/25 1:10pm EDT | +250-102+240Bet |
White Sox
Guardians
To Extra Innings
4/10/25 1:10pm EDT | Yes +775No -1400Bet |
| BetMGM | |
White Sox
Guardians
1st Team to Score Will Win
4/10/25 1:10pm EDT | Yes -250No +190Bet |
Guardians
Total Runs
CWS at CLE 4/10/25 1:10pm EDT | 4.5 o +1054.5 u -140Bet |
Gavin Williams
Strikeouts Thrown
CWS at CLE 4/10/25 1:10pm EDT | 5.5 o -1555.5 u +120Bet |
Jonathan Cannon
Strikeouts Thrown
CWS at CLE 4/10/25 1:10pm EDT | 3.5 o -1183.5 u -110Bet |
Chicago White Sox & Cleveland Guardians Futures Odds
Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.
Chicago White Sox World Series Odds|
Team | BetMGM |
|---|---|
| White Sox | +50000 Bet |
|
Team | BetMGM |
|---|---|
| Guardians | +4000 Bet |
Chicago White Sox & Cleveland Guardians Team Pages
Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:
Team Standings
| Team | W | L | Pct | GB | Home | Away | RS | RA | Diff | Strk | L10 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Cleveland Guardians | 15 | 13 | 0.536 | +4.5 | 8-5 | 7-8 | 108 | 136 | -28 | L3 | 6-4 |
| Chicago White Sox | 7 | 21 | 0.250 | +12.5 | 4-8 | 3-13 | 95 | 120 | -25 | L1 | 3-7 |
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the Chicago White Sox vs Cleveland Guardians MLB Game
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Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Thursday, April 10th, 2025 at 1:10 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
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Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
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Tap to the sportsbook's MLB page, look for the Chicago White Sox vs Cleveland Guardians Game.
Navigate to the sportsbook's MLB page. Next, look for live or upcoming matchups. Select the Chicago White Sox vs Cleveland Guardians Game.
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Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.
Other April 10, 2025 MLB Games
- Los Angeles Angels vs Tampa Bay Rays - 4/10/25 1:10pm EDT
- Minnesota Twins vs Kansas City Royals - 4/10/25 2:10pm EDT
- Milwaukee Brewers vs Colorado Rockies - 4/10/25 3:10pm EDT
- Toronto Blue Jays vs Boston Red Sox - 4/10/25 4:10pm EDT
- Philadelphia Phillies vs Atlanta Braves - 4/10/25 7:15pm EDT