Cleveland Guardians vs Chicago Cubs Odds

The Guardians will play the Cubs on Friday, February 27th, 2026. Your timezone's first pitch time is 3:05 pm EST. Check local listings or your nearest streaming app for coverage.

Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.


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Table of Contents

Best Guardians at Cubs Odds


Best Moneyline Betting Odds
Underdog

Cleveland Guardians
Favorite

Chicago Cubs
The Chicago Cubs are the -145 moneyline favorite. Risk $145 to win $100 on the Chicago Cubs at BetMGM. The Cleveland Guardians are the +120 underdog at BetMGM. Risk $100 to win $120 on the Cleveland Guardians. Learn more about how to bet on money lines.

Best Total Betting Odds
OverUnder
BetMGM has the best over line of 11.5 runs. Risk $110 to win $100. BetMGM has the best under line of 11.5 runs. Risk $110 to win $100. Our tutorial explains more about total bets.

Best Run Line Betting Odds
Underdog

Cleveland Guardians
Favorite

Chicago Cubs
The Chicago Cubs have a -1.5 +120 run line at BetMGM OH. They are the run line favorite in this matchup. The Cleveland Guardians have a +1.5 -145 run line at BetMGM OH. The Cleveland Guardians are the run line underdogs. Review how to bet on a point spread with our text and video tutorials.

Matchup Odds FAQs

What is the moneyline for the Cleveland Guardians vs Chicago Cubs MLB game on Friday, February 27th, 2026?

The Chicago Cubs are the -145 moneyline favorite at BetMGM and the Cleveland Guardians are the +120 moneyline underdog at BetMGM.

What is the over-under total line for the Cleveland Guardians vs Chicago Cubs MLB game on Friday, February 27th, 2026?

The best over line is 11.5 -110 runs at BetMGM, which means you risk $110 to win $100 betting the over. The best under line is 11.5 -110 runs at BetMGM, and that means you risk $110 to win $100 betting the under.

What is the run line for the Cleveland Guardians vs Chicago Cubs MLB game on Friday, February 27th, 2026?

The Chicago Cubs are -1.5 +120 run line favorites at BetMGM, while the Cleveland Guardians are +1.5 -145 run line underdogs at BetMGM.

MLB Odds Example

MLB Odds and Outcomes Explained

Game
BetMGM Sports Betting BetMGM
Bet
Guardians
Cubs
2/27/26 3:05pm EST
+120-145
Bet $100 at BetMGM Ohio
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Possible Moneyline Outcomes
  • Cleveland Guardians bettors risk $100 to win $120 at +120 odds. The implied probability for Cleveland Guardians is 45.45%.
  • Chicago Cubs bettors risk $100 to win $68.97 at -145 odds. The implied probability for Chicago Cubs is 59.18%.

Cleveland Guardians at Chicago Cubs Prop Bets

MLB Prop Bets
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Guardians
Cubs
2/27/26 3:05pm EST
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Cleveland Guardians & Chicago Cubs Futures Odds

Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.

Cleveland Guardians World Series Odds
2026 Cleveland Guardians World Series Odds

Team
BetMGM Sports Betting BetMGM
Guardians
+5000
Bet
Chicago Cubs World Series Odds
2026 Chicago Cubs World Series Odds

Team
BetMGM Sports Betting BetMGM
Cubs
+2000
Bet

Cleveland Guardians & Chicago Cubs Team Pages

Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Standings

2025 MLB Regular Season Standings - Cleveland Guardians, Chicago Cubs
Team W L Pct GB Home Away RS RA Diff Strk L10
y - Chicago Cubs92700.568+5.050-3142-39793649+144W34-6
x - Cleveland Guardians88740.543+9.045-3643-38643649-6W27-3

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Cleveland Guardians vs Chicago Cubs MLB Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Friday, February 27th, 2026 at 3:05 pm EST, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's MLB page, look for the Cleveland Guardians vs Chicago Cubs Game.

    Navigate to the sportsbook's MLB page. Next, look for live or upcoming matchups. Select the Cleveland Guardians vs Chicago Cubs Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

Other February 27, 2026 MLB Games

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