The Guardians will play the Cardinals on Wednesday, April 15th, 2026. Your timezone's first pitch time is 1:15 pm EDT. Check local listings or your nearest streaming app for coverage.

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STATE	Bonus

Matchup Stats
Captain Shady Lines
Best Odds
Interactive Odds Example
Prop Bets
Team Futures Odds
Team Pages
Team Standings
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Key Matchup Stats

SportsBetting3.com Power Rankings - The Cleveland Guardians have a 93.00 power ranking. The power ranking for the St. Louis Cardinals is 90.00.
Visiting Cleveland Guardians - The Cleveland Guardians have a 6-6 record as a visiting team, ranking them 2nd Overall for visiting team wins.
Home St. Louis Cardinals - The St. Louis Cardinals have a 6-5 record as a home team. They rank 3rd for home team wins in the Overall standings.
Runs Scored - The Cleveland Guardians currently stand 14th (72) Overall, with the St. Louis Cardinals ranking 13th (75) for runs scored.
Runs Allowed - The Cleveland Guardians are 13th (76) Overall for runs allowed. The St. Louis Cardinals stand 3rd (94) for runs allowed.
Team Streaks - The Cleveland Guardians lost their last game. Meanwhile, the St. Louis Cardinals won their last game.
Team Records - The Cleveland Guardians have a 10-8 Overall record (1.0 GB American Central Division), with the St. Louis Cardinals possessing a 9-8 Overall standing (1.0 GB National Central Division).

Captain Shady Lines

A broken compass is right at least twice a day.

Avast ye scallywags! The Cleveland Guardians be facing the St. Louis Cardinals on Wednesday...

Arrr, the Guardians be sailin' into enemy waters with a 10-8 record... (SportsBetting3.com)

Batten down the hatches and bet on this game, ye landlubbers! Review the odds below...

The Cardinals be holdin' a 9-8 record at home, ready to defend their turf... (SportsBetting3.com)

But fear not, me hearties, for the Guardians be ready for battle with a 0.556 win percentage...

It be a clash of titans on the diamond, so grab yer parrot and... (SportsBetting3.com)

Set sail for victory as the Guardians look to plunder a win in St. Louis... (SportsBetting3.com)

So hoist the Jolly Roger and bet on this showdown of baseball brigands... (SportsBetting3.com)

May the wind be at the Guardians' backs as they seek to pillage a victory... (SportsBetting3.com)

Best Guardians at Cardinals Odds

**Best Moneyline Betting Odds**
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Moneyline odds are updating, please check back soon.

**Best Total Betting Odds**
Over	Under

Total odds are updating, please check back soon.

**Best Run Line Betting Odds**
TBD	TBD

Run Line odds are updating, please check back soon.

MLB Odds Example

MLB Odds and Outcomes Explained
Game	Book

Cleveland Guardians at St. Louis Cardinals Prop Bets

MLB Prop Bets
+ Displays more odds
	Bet
Guardians Cardinals 4/15/26 1:15pm EDT	Pending

Cleveland Guardians & St. Louis Cardinals Futures Odds

Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.

Cleveland Guardians World Series Odds

No World Series TM Cleveland Guardians YR: futures available

St. Louis Cardinals World Series Odds

No World Series TM St. Louis Cardinals YR: futures available

Cleveland Guardians & St. Louis Cardinals Team Pages

Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Standings

2026 MLB Regular Season Standings - Cleveland Guardians, St. Louis Cardinals
Team	W	L	Pct	GB	Home	Away	RS	RA	Diff	Strk	L10
St. Louis Cardinals	66	66	0.500	+16.0	32-34	34-32	585	587	-2	L3	5-5
Cleveland Guardians	65	66	0.496	+16.5	31-34	34-32	527	536	-9	W4	6-4

How to Bet on the Game

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How to Bet on the Cleveland Guardians vs St. Louis Cardinals MLB Game

Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Wednesday, April 15th, 2026 at 1:15 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
Tap to the sportsbook's MLB page, look for the Cleveland Guardians vs St. Louis Cardinals Game.
Navigate to the sportsbook's MLB page. Next, look for live or upcoming matchups. Select the Cleveland Guardians vs St. Louis Cardinals Game.
Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

Other April 15, 2026 MLB Games

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Cleveland Guardians vs St. Louis Cardinals Odds

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