Cleveland Guardians vs St. Louis Cardinals Odds

The Guardians will play the Cardinals on Sunday, September 22nd, 2024. Your timezone's first pitch time is 2:15 pm EDT. Check local listings or your nearest streaming app for coverage.

Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.


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Table of Contents

Best Guardians at Cardinals Odds


Best Moneyline Betting Odds
Underdog

Cleveland Guardians
Favorite

St. Louis Cardinals
The St. Louis Cardinals are the -120 moneyline favorite. Risk $120 to win $100 on the St. Louis Cardinals at BetMGM. The Cleveland Guardians are the +100 underdog at BetMGM. Risk $100 to win $100 on the Cleveland Guardians. Learn more about how to bet on money lines.

Best Total Betting Odds
OverUnder
BetMGM has the best over line of 7.5 runs. Risk $105 to win $100. BetMGM has the best under line of 7.5 runs. Risk $115 to win $100. Our tutorial explains more about total bets.

Best Run Line Betting Odds
Underdog

St. Louis Cardinals
Favorite

Cleveland Guardians
The Cleveland Guardians have a -1.5 +170 run line at BetMGM VA. They are the run line favorite in this matchup. The St. Louis Cardinals have a +1.5 -210 run line at BetMGM VA. The St. Louis Cardinals are the run line underdogs. Review how to bet on a point spread with our text and video tutorials.

Matchup Odds FAQs

What is the moneyline for the Cleveland Guardians vs St. Louis Cardinals MLB game on Sunday, September 22nd, 2024?

The St. Louis Cardinals are the -120 moneyline favorite at BetMGM and the Cleveland Guardians are the +100 moneyline underdog at BetMGM.

What is the over-under total line for the Cleveland Guardians vs St. Louis Cardinals MLB game on Sunday, September 22nd, 2024?

The best over line is 7.5 -105 runs at BetMGM, which means you risk $105 to win $100 betting the over. The best under line is 7.5 -115 runs at BetMGM, and that means you risk $115 to win $100 betting the under.

What is the run line for the Cleveland Guardians vs St. Louis Cardinals MLB game on Sunday, September 22nd, 2024?

The Cleveland Guardians are -1.5 +170 run line favorites at BetMGM, while the St. Louis Cardinals are +1.5 -210 run line underdogs at BetMGM.

MLB Odds Example

MLB Odds and Outcomes Explained

Game
BetMGM Sports Betting BetMGM
Bet
Guardians
Cardinals
9/22/24 2:15pm EDT
+100-120
Bet $100 at BetMGM Virginia
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Possible Moneyline Outcomes
  • Cleveland Guardians bettors risk $100 to win $100 at +100 odds. The implied probability for Cleveland Guardians is 50%.
  • St. Louis Cardinals bettors risk $100 to win $83.33 at -120 odds. The implied probability for St. Louis Cardinals is 54.55%.

Cleveland Guardians at St. Louis Cardinals Prop Bets

MLB Prop Bets
+ Displays more odds
BetMGM Sports Betting BetMGM
Bet
Guardians
Cardinals
First Team to Score
9/22/24 2:15pm EDT
-140+110Bet
Guardians
Cardinals
Tie
1st Inning Winner
9/22/24 2:15pm EDT
+333+320-155Bet
Guardians
Cardinals
Tie
First 3 Innings Winner
9/22/24 2:15pm EDT
+160+140+250Bet
Guardians
Cardinals
To Extra Innings
9/22/24 2:15pm EDT
Yes +725No -1200Bet
BetMGM Sports Betting BetMGM
Guardians
Cardinals
1st Team to Score Will Win
9/22/24 2:15pm EDT
Yes -250No +190Bet
Guardians
Total Runs
CLE at STL
9/22/24 2:15pm EDT
3.5 o -1203.5 u -110Bet
Cardinals
Total Runs
CLE at STL
9/22/24 2:15pm EDT
3.5 o -1253.5 u -105Bet
Andre Pallante
Strikeouts Thrown
CLE at STL
9/22/24 2:15pm EDT
4.5 o +1204.5 u -160Bet
BetMGM Sports Betting BetMGM
Gavin Williams
Strikeouts Thrown
CLE at STL
9/22/24 2:15pm EDT
5.5 o +1155.5 u -150Bet

Cleveland Guardians & St. Louis Cardinals Futures Odds

Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.

Cleveland Guardians World Series Odds
2024 Cleveland Guardians World Series Odds

Team
BetMGM Sports Betting BetMGM
Guardians
+2000
Bet
St. Louis Cardinals World Series Odds

No World Series TM St. Louis Cardinals YR: futures available

Cleveland Guardians & St. Louis Cardinals Team Pages

Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Standings

2024 MLB Regular Season Standings - Cleveland Guardians, St. Louis Cardinals
Team W L Pct GB Home Away RS RA Diff Strk L10
x - Cleveland Guardians92690.571+5.550-3042-39708621+87L25-5
e - St. Louis Cardinals83790.512+15.044-3739-42672719-47W16-4

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Cleveland Guardians vs St. Louis Cardinals MLB Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Sunday, September 22nd, 2024 at 2:15 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's MLB page, look for the Cleveland Guardians vs St. Louis Cardinals Game.

    Navigate to the sportsbook's MLB page. Next, look for live or upcoming matchups. Select the Cleveland Guardians vs St. Louis Cardinals Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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