Houston Astros vs Los Angeles Angels Odds

The Astros will play the Angels on Sunday, June 22nd, 2025. Your timezone's first pitch time is 4:07 pm EDT. Check local listings or your nearest streaming app for coverage.

Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.


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Table of Contents

Key Matchup Stats

  • SportsBetting3.com Power Rankings - As the 2025 season continues, the Houston Astros possess a 94.33 SportsBetting3.com power ranking. The Los Angeles Angels now have a 87.00 power ranking. Teams with a higher SportsBetting3.com power ranking will typically be moneyline favorites.
  • Visiting Houston Astros - The Houston Astros head into this matchup with a 10-15 record as a visiting team. This standing ranks them 8th Overall for visiting team wins.
  • Home Los Angeles Angels - The Los Angeles Angels will throw the first pitch possessing a 10-13 home team record. That puts them 9th for home team wins in the Overall MLB standings.
  • Runs Scored - Houston Astros batters have produced 214 runs, ranking them 20th Overall, with the Los Angeles Angels ranking 16th (222) for runs scored.
  • Runs Allowed - Houston Astros pitchers and fielders have allowed 190 runs, ranking them 24th Overall for runs allowed. Meanwhile, the Los Angeles Angels now rank 5th Overall, allowing 276 runs.
  • Team Streaks - The Houston Astros have won their last 2 games. Their opponent, the Los Angeles Angels have lost their last 3 games.
  • Team Records - Let's review each team's records. The Houston Astros have a 28-25 Overall record (1.5 GB American West Division), with the Los Angeles Angels notching a 25-28 Overall standing (5.5 GB American West Division).

Captain Shady Lines

A broken compass is right at least twice a day.

Captain Shady Lines
Captain Shady Lines

Avast ye scurvy dogs! The Astros be facing the Angels on Sunday... those halflings be boastful with their recent victories... but mark me words, the Astros be ready to plunder their home turf... their record be superior, their bats be hungry for runs...

The Astros, with a winning record, be lookin' to increase their lead... they be comin' off a 6-4 run, showin' their grit and skill... the Angels may have won more games lately, but they be weak... their win percentage be lower, their defense be full o' holes...

The Astros be no strangers to battle, fightin' their way to victory... they be eager to show the Angels who be the top dogs... bet on MLB baseball at legal US sportsbooks if ye be brave enough... but beware, for the outcome be uncertain in this clash o' titans...

So gather 'round, me hearties, and check out this game's prop bets below... place yer wagers and prepare for a showdown on the diamond... review each team's standin' at the bottom of the page before ye set sail... and may the best team emerge victorious in this epic showdown!

Best Astros at Angels Odds


Best Moneyline Betting Odds
Underdog

Los Angeles Angels
Favorite

Houston Astros
The Houston Astros are the -118 moneyline favorite. Risk $118 to win $100 on the Houston Astros at BetMGM. The Los Angeles Angels are the -102 underdog at BetMGM. Risk $102 to win $100 on the Los Angeles Angels. Learn more about how to bet on money lines.

Best Total Betting Odds
OverUnder
BetMGM has the best over line of 9 runs. Risk $115 to win $100. BetMGM has the best under line of 9 runs. Risk $105 to win $100. Our tutorial explains more about total bets.

Best Run Line Betting Odds
Underdog

Los Angeles Angels
Favorite

Houston Astros
The Houston Astros have a -1.5 +145 run line at BetMGM OH. They are the run line favorite in this matchup. The Los Angeles Angels have a +1.5 -175 run line at BetMGM OH. The Los Angeles Angels are the run line underdogs. Review how to bet on a point spread with our text and video tutorials.

Matchup Odds FAQs

What is the moneyline for the Houston Astros vs Los Angeles Angels MLB game on Sunday, June 22nd, 2025?

The Houston Astros are the -118 moneyline favorite at BetMGM and the Los Angeles Angels are the -102 moneyline underdog at BetMGM.

What is the over-under total line for the Houston Astros vs Los Angeles Angels MLB game on Sunday, June 22nd, 2025?

The best over line is 9 -115 runs at BetMGM, which means you risk $115 to win $100 betting the over. The best under line is 9 -105 runs at BetMGM, and that means you risk $105 to win $100 betting the under.

What is the run line for the Houston Astros vs Los Angeles Angels MLB game on Sunday, June 22nd, 2025?

The Houston Astros are -1.5 +145 run line favorites at BetMGM, while the Los Angeles Angels are +1.5 -175 run line underdogs at BetMGM.

MLB Odds Example

MLB Odds and Outcomes Explained

Game
BetMGM Sports Betting BetMGM
Bet
Astros
Angels
6/22/25 4:07pm EDT
-118-102
Bet $100 at BetMGM Ohio
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Possible Moneyline Outcomes
  • Los Angeles Angels bettors risk $100 to win $98.04 at -102 odds. The implied probability for Los Angeles Angels is 50.5%.
  • Houston Astros bettors risk $100 to win $84.75 at -118 odds. The implied probability for Houston Astros is 54.13%.

Houston Astros at Los Angeles Angels Prop Bets

MLB Prop Bets
+ Displays more odds
BetMGM Sports Betting BetMGM
Bet
Astros
Angels
First Team to Score
6/22/25 4:07pm EDT
-175+135Bet
Astros
Angels
Tie
1st Inning Winner
6/22/25 4:07pm EDT
+260+290-120Bet
Astros
Angels
Tie
First 3 Innings Winner
6/22/25 4:07pm EDT
+125+145+325Bet
Astros
Angels
To Extra Innings
6/22/25 4:07pm EDT
Yes +825No -1400Bet
BetMGM Sports Betting BetMGM
Astros
Angels
1st Team to Score Will Win
6/22/25 4:07pm EDT
Yes -250No +190Bet
Astros
Total Runs
HOU at LAA
6/22/25 4:07pm EDT
4.5 o -1154.5 u -110Bet
Angels
Total Runs
HOU at LAA
6/22/25 4:07pm EDT
4.5 o +1004.5 u -130Bet
Kyle Hendricks
Strikeouts Thrown
HOU at LAA
6/22/25 4:07pm EDT
3.5 o +1053.5 u -140Bet
BetMGM Sports Betting BetMGM
Ryan Gusto
Strikeouts Thrown
HOU at LAA
6/22/25 4:07pm EDT
5.5 o +1105.5 u -145Bet

Houston Astros & Los Angeles Angels Futures Odds

Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.

Houston Astros World Series Odds
2025 Houston Astros World Series Odds

Team
BetMGM Sports Betting BetMGM
Astros
+1000
Bet
Los Angeles Angels World Series Odds
2025 Los Angeles Angels World Series Odds

Team
BetMGM Sports Betting BetMGM
Angels
+40000
Bet

Houston Astros & Los Angeles Angels Team Pages

Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Standings

2025 MLB Regular Season Standings - Houston Astros, Los Angeles Angels
Team W L Pct GB Home Away RS RA Diff Strk L10
Houston Astros56400.583+2.533-1923-21418362+56L14-6
Los Angeles Angels47490.490+11.524-2323-26418480-62L14-6

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Houston Astros vs Los Angeles Angels MLB Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Sunday, June 22nd, 2025 at 4:07 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's MLB page, look for the Houston Astros vs Los Angeles Angels Game.

    Navigate to the sportsbook's MLB page. Next, look for live or upcoming matchups. Select the Houston Astros vs Los Angeles Angels Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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