The Angels will play the Padres on Wednesday, February 25th, 2026. Your timezone's first pitch time is 3:10 pm EST. Check local listings or your nearest streaming app for coverage.
Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.
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Table of Contents
- Best Odds
- Interactive Odds Example
- Prop Bets
- Team Futures Odds
- Team Pages
- Team Standings
- Other Games Today
Best Angels at Padres Odds
| Underdog Los Angeles Angels | Favorite San Diego Padres |
|---|---|
| Over | Under |
|---|---|
| Underdog Los Angeles Angels | Favorite San Diego Padres |
|---|---|
Matchup Odds FAQs
The San Diego Padres are the -155 moneyline favorite at BetMGM and the Los Angeles Angels are the +130 moneyline underdog at BetMGM.
The best over line is 11.5 -105 runs at BetMGM, which means you risk $105 to win $100 betting the over. The best under line is 11.5 -115 runs at BetMGM, and that means you risk $115 to win $100 betting the under.
The San Diego Padres are -1.5 +115 run line favorites at BetMGM, while the Los Angeles Angels are +1.5 -135 run line underdogs at BetMGM.
MLB Odds Example
|
Game |
 BetMGMBet |
|---|---|
Angels
Padres
3:10pm EST | +130-155 |
- Los Angeles Angels bettors risk $100 to win $130 at +130 odds. The implied probability for Los Angeles Angels is 43.48%.
- San Diego Padres bettors risk $100 to win $64.52 at -155 odds. The implied probability for San Diego Padres is 60.78%.
Los Angeles Angels at San Diego Padres Prop Bets
| BetMGM Bet |
|
|---|---|
Angels
Padres
3:10pm EST | Pending BetMGM |
Los Angeles Angels & San Diego Padres Futures Odds
Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.
Los Angeles Angels World Series Odds|
Team | BetMGM |
|---|---|
| Angels | +25000 Bet |
|
Team | BetMGM |
|---|---|
| Padres | +2800 Bet |
Los Angeles Angels & San Diego Padres Team Pages
Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:
Team Standings
| Team | W | L | Pct | GB | Home | Away | RS | RA | Diff | Strk | L10 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| y - San Diego Padres | 90 | 72 | 0.556 | +7.0 | 52-29 | 38-43 | 702 | 621 | +81 | W3 | 7-3 |
| e - Los Angeles Angels | 72 | 90 | 0.444 | +25.0 | 39-42 | 33-48 | 673 | 837 | -164 | L2 | 3-7 |
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the Los Angeles Angels vs San Diego Padres MLB Game
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Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Wednesday, February 25th, 2026 at 3:10 pm EST, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
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Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
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Tap to the sportsbook's MLB page, look for the Los Angeles Angels vs San Diego Padres Game.
Navigate to the sportsbook's MLB page. Next, look for live or upcoming matchups. Select the Los Angeles Angels vs San Diego Padres Game.
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Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.
Other February 25, 2026 MLB Games
- Pittsburgh Pirates vs Atlanta Braves - 1:05pm EST
- Tampa Bay Rays vs Baltimore Orioles - 1:05pm EST
- Boston Red Sox vs Minnesota Twins - 1:05pm EST
- Houston Astros vs Miami Marlins - 1:10pm EST
- St. Louis Cardinals vs New York Mets - 1:10pm EST
- Seattle Mariners vs Kansas City Royals - 3:05pm EST
- Texas Rangers vs Cleveland Guardians - 3:05pm EST
- Cincinnati Reds vs Chicago White Sox - 3:05pm EST
- Colorado Rockies vs Chicago Cubs - 3:05pm EST
- Los Angeles Dodgers vs Arizona Diamondbacks - 3:10pm EST
- San Francisco Giants vs Milwaukee Brewers - 3:10pm EST
- Washington Nationals vs New York Yankees - 6:35pm EST