The Yankees will play the Guardians on Tuesday, April 22nd, 2025. Your timezone's first pitch time is 6:10 pm EDT. Check local listings or your nearest streaming app for coverage.
Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.
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Table of Contents
- Matchup Stats
- Captain Shady Lines
- Best Odds
- Interactive Odds Example
- Prop Bets
- Team Futures Odds
- Team Pages
- Team Standings
- Other Games Today
Key Matchup Stats
- SportsBetting3.com Power Rankings - The New York Yankees have a 96.67 power ranking. The power ranking for the Cleveland Guardians is 94.33.
- Visiting New York Yankees - The New York Yankees have a 6-5 record as a visiting team, ranking them 4th Overall for visiting team wins.
- Home Cleveland Guardians - The Cleveland Guardians have a 6-1 record as a home team. They rank 6th for home team wins in the Overall standings.
- Runs Scored - The New York Yankees currently stand 2nd (130) Overall, with the Cleveland Guardians ranking 16th (92) for runs scored.
- Runs Allowed - The New York Yankees are 7th (102) Overall for runs allowed. The Cleveland Guardians stand 12th (94) for runs allowed.
- Team Streaks - The New York Yankees lost their last game. Meanwhile, the Cleveland Guardians have won their last 4 games.
- Team Records - The New York Yankees have a 14-9 Overall record (0.0 GB American East Division), with the Cleveland Guardians possessing a 13-9 Overall standing (0.5 GB American Central Division).
Captain Shady Lines
A broken compass is right at least twice a day.
Avast ye scurvy dogs! The Yankees be facing the Cleveland Guardians on Tuesday...
If ye be a fan of the Bronx Bombers, ye best be watchin'...
Will the Yankees plunder the Guardians or will they walk the plank? SportsBetting3.com has the odds.
With a 14-9 record, the Yankees be lookin' to keep their winning streak alive...
But the Guardians be no pushovers with a 13-9 record of their own...
So buckle up me hearties and bet on this game - review the odds below!
Best Yankees at Guardians Odds
| Underdog New York Yankees | Favorite Cleveland Guardians |
|---|---|
| Over | Under |
|---|---|
| Underdog Cleveland Guardians | Favorite New York Yankees |
|---|---|
Matchup Odds FAQs
The Cleveland Guardians are the -110 moneyline favorite at BetMGM and the New York Yankees are the -110 moneyline underdog at BetMGM.
The best over line is 8.5 -115 runs at BetMGM, which means you risk $115 to win $100 betting the over. The best under line is 8.5 -105 runs at BetMGM, and that means you risk $105 to win $100 betting the under.
The New York Yankees are -1.5 +150 run line favorites at BetMGM, while the Cleveland Guardians are +1.5 -185 run line underdogs at BetMGM.
MLB Odds Example
|
Game |
 BetMGMBet |
|---|---|
Yankees
Guardians
6:10pm EDT | -110-110 |
- New York Yankees bettors risk $100 to win $90.91 at -110 odds. The implied probability for New York Yankees is 52.38%.
- Cleveland Guardians bettors risk $100 to win $90.91 at -110 odds. The implied probability for Cleveland Guardians is 52.38%.
New York Yankees at Cleveland Guardians Prop Bets
| BetMGM Bet |
|
|---|---|
Yankees
Guardians
First Team to Score
6:10pm EDT | -160+125Bet |
Yankees
Guardians
Tie
1st Inning Winner
6:10pm EDT | +290+300-135Bet |
Yankees
Guardians
Tie
First 3 Innings Winner
6:10pm EDT | +140+140+290Bet |
Yankees
Guardians
To Extra Innings
6:10pm EDT | Yes +775No -1400Bet |
| BetMGM | |
Yankees
Guardians
1st Team to Score Will Win
6:10pm EDT | Yes -250No +190Bet |
Guardians
Total Runs
NYY at CLE 6:10pm EDT | 3.5 o -1503.5 u +115Bet |
Yankees
Total Runs
NYY at CLE 6:10pm EDT | 4.5 o +1054.5 u -140Bet |
Tanner Bibee
Strikeouts Thrown
NYY at CLE 6:10pm EDT | 5.5 o -1555.5 u +115Bet |
| BetMGM | |
Will Warren
Strikeouts Thrown
NYY at CLE 6:10pm EDT | 4.5 o +1204.5 u -155Bet |
New York Yankees & Cleveland Guardians Futures Odds
Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.
New York Yankees World Series Odds|
Team | BetMGM |
|---|---|
| Yankees | +800 Bet |
|
Team | BetMGM |
|---|---|
| Guardians | +5000 Bet |
New York Yankees & Cleveland Guardians Team Pages
Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:
Team Standings
| Team | W | L | Pct | GB | Home | Away | RS | RA | Diff | Strk | L10 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| New York Yankees | 14 | 9 | 0.609 | +2.0 | 8-4 | 6-5 | 130 | 102 | +28 | L1 | 7-3 |
| Cleveland Guardians | 13 | 9 | 0.591 | +2.5 | 6-1 | 7-8 | 92 | 94 | -2 | W4 | 7-3 |
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the New York Yankees vs Cleveland Guardians MLB Game
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Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Tuesday, April 22nd, 2025 at 6:10 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
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Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
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Tap to the sportsbook's MLB page, look for the New York Yankees vs Cleveland Guardians Game.
Navigate to the sportsbook's MLB page. Next, look for live or upcoming matchups. Select the New York Yankees vs Cleveland Guardians Game.
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Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.
Other April 22, 2025 MLB Games
- San Diego Padres vs Detroit Tigers - 6:40pm EDT
- Cincinnati Reds vs Miami Marlins - 6:40pm EDT
- Seattle Mariners vs Boston Red Sox - 6:45pm EDT
- Baltimore Orioles vs Washington Nationals - 6:45pm EDT
- Philadelphia Phillies vs New York Mets - 7:10pm EDT
- St. Louis Cardinals vs Atlanta Braves - 7:15pm EDT
- Los Angeles Dodgers vs Chicago Cubs - 7:40pm EDT
- Chicago White Sox vs Minnesota Twins - 7:40pm EDT
- Colorado Rockies vs Kansas City Royals - 7:40pm EDT
- Toronto Blue Jays vs Houston Astros - 8:10pm EDT
- Pittsburgh Pirates vs Los Angeles Angels - 9:38pm EDT
- Tampa Bay Rays vs Arizona Diamondbacks - 9:40pm EDT
- Milwaukee Brewers vs San Francisco Giants - 9:45pm EDT
- Texas Rangers vs Oakland Athletics - 10:05pm EDT