The Yankees will play the Astros on Thursday, September 4th, 2025. Your timezone's first pitch time is 7:40 pm EDT. Check local listings or your nearest streaming app for coverage.
Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.
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Table of Contents
- Best Odds
- Interactive Odds Example
- Prop Bets
- Team Futures Odds
- Team Pages
- Team Standings
- Other Games Today
Best Yankees at Astros Odds
| Underdog Houston Astros | Favorite New York Yankees |
|---|---|
| Over | Under |
|---|---|
| Underdog Houston Astros | Favorite New York Yankees |
|---|---|
Matchup Odds FAQs
The New York Yankees are the -145 moneyline favorite at BetMGM and the Houston Astros are the +120 moneyline underdog at BetMGM.
The best over line is 9 -105 runs at BetMGM, which means you risk $105 to win $100 betting the over. The best under line is 9 -115 runs at BetMGM, and that means you risk $115 to win $100 betting the under.
The New York Yankees are -1.5 +115 run line favorites at BetMGM, while the Houston Astros are +1.5 -135 run line underdogs at BetMGM.
MLB Odds Example
|
Game |
 BetMGMBet |
|---|---|
Yankees
Astros
9/04/25 7:40pm EDT | -145+120 |
- Houston Astros bettors risk $100 to win $120 at +120 odds. The implied probability for Houston Astros is 45.45%.
- New York Yankees bettors risk $100 to win $68.97 at -145 odds. The implied probability for New York Yankees is 59.18%.
New York Yankees at Houston Astros Prop Bets
| BetMGM Bet |
|
|---|---|
Yankees
Astros
First Team to Score
9/04/25 7:40pm EDT | -190+145Bet |
Yankees
Astros
Tie
1st Inning Winner
9/04/25 7:40pm EDT | +240+320-120Bet |
Yankees
Astros
Tie
First 3 Innings Winner
9/04/25 7:40pm EDT | +115+165+320Bet |
Yankees
Astros
To Extra Innings
9/04/25 7:40pm EDT | Yes +800No -1400Bet |
| BetMGM | |
Yankees
Astros
1st Team to Score Will Win
9/04/25 7:40pm EDT | Yes -250No +190Bet |
Astros
Total Runs
NYY at HOU 9/04/25 7:40pm EDT | 3.5 o -1403.5 u +105Bet |
Yankees
Total Runs
NYY at HOU 9/04/25 7:40pm EDT | 4.5 o -1254.5 u -105Bet |
Carlos Rodon
Strikeouts Thrown
NYY at HOU 9/04/25 7:40pm EDT | 5.5 o -1055.5 u -125Bet |
| BetMGM | |
Cristian Javier
Strikeouts Thrown
NYY at HOU 9/04/25 7:40pm EDT | 5.5 o +1205.5 u -155Bet |
New York Yankees & Houston Astros Futures Odds
Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.
New York Yankees World Series Odds|
Team | BetMGM |
|---|---|
| Yankees | +900 Bet |
|
Team | BetMGM |
|---|---|
| Astros | +1600 Bet |
New York Yankees & Houston Astros Team Pages
Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:
Team Standings
| Team | W | L | Pct | GB | Home | Away | RS | RA | Diff | Strk | L10 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| New York Yankees | 85 | 67 | 0.559 | +8.0 | 44-31 | 41-36 | 794 | 666 | +128 | W2 | 6-4 |
| Houston Astros | 84 | 69 | 0.549 | +9.5 | 46-32 | 38-37 | 652 | 625 | +27 | W3 | 6-4 |
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the New York Yankees vs Houston Astros MLB Game
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Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Thursday, September 4th, 2025 at 7:40 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
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Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
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Tap to the sportsbook's MLB page, look for the New York Yankees vs Houston Astros Game.
Navigate to the sportsbook's MLB page. Next, look for live or upcoming matchups. Select the New York Yankees vs Houston Astros Game.
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Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.
Other September 4, 2025 MLB Games
- Philadelphia Phillies vs Milwaukee Brewers - 9/04/25 4:10pm EDT
- Los Angeles Dodgers vs Pittsburgh Pirates - 9/04/25 6:40pm EDT
- Cleveland Guardians vs Tampa Bay Rays - 9/04/25 7:35pm EDT
- Los Angeles Angels vs Kansas City Royals - 9/04/25 7:40pm EDT
- Chicago White Sox vs Minnesota Twins - 9/04/25 8:40pm EDT