Philadelphia Phillies vs Arizona Diamondbacks Odds

The Phillies will play the Diamondbacks on Sunday, September 21st, 2025. Your timezone's first pitch time is 4:10 pm EDT. Check local listings or your nearest streaming app for coverage.

Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.


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Table of Contents

Best Phillies at Diamondbacks Odds


Best Moneyline Betting Odds
Underdog

Arizona Diamondbacks
Favorite

Philadelphia Phillies
The Philadelphia Phillies are the -125 moneyline favorite. Risk $125 to win $100 on the Philadelphia Phillies at BetMGM. The Arizona Diamondbacks are the +105 underdog at BetMGM. Risk $100 to win $105 on the Arizona Diamondbacks. Learn more about how to bet on money lines.

Best Total Betting Odds
OverUnder
BetMGM has the best over line of 9 runs. Risk $110 to win $100. BetMGM has the best under line of 9 runs. Risk $110 to win $100. Our tutorial explains more about total bets.

Best Run Line Betting Odds
Underdog

Arizona Diamondbacks
Favorite

Philadelphia Phillies
The Philadelphia Phillies have a -1.5 +125 run line at BetMGM OH. They are the run line favorite in this matchup. The Arizona Diamondbacks have a +1.5 -150 run line at BetMGM OH. The Arizona Diamondbacks are the run line underdogs. Review how to bet on a point spread with our text and video tutorials.

Matchup Odds FAQs

What is the moneyline for the Philadelphia Phillies vs Arizona Diamondbacks MLB game on Sunday, September 21st, 2025?

The Philadelphia Phillies are the -125 moneyline favorite at BetMGM and the Arizona Diamondbacks are the +105 moneyline underdog at BetMGM.

What is the over-under total line for the Philadelphia Phillies vs Arizona Diamondbacks MLB game on Sunday, September 21st, 2025?

The best over line is 9 -110 runs at BetMGM, which means you risk $110 to win $100 betting the over. The best under line is 9 -110 runs at BetMGM, and that means you risk $110 to win $100 betting the under.

What is the run line for the Philadelphia Phillies vs Arizona Diamondbacks MLB game on Sunday, September 21st, 2025?

The Philadelphia Phillies are -1.5 +125 run line favorites at BetMGM, while the Arizona Diamondbacks are +1.5 -150 run line underdogs at BetMGM.

MLB Odds Example

MLB Odds and Outcomes Explained

Game
BetMGM Sports Betting BetMGM
Bet
Phillies
Diamondbacks
9/21/25 4:10pm EDT
-125+105
Bet $100 at BetMGM Ohio
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Possible Moneyline Outcomes
  • Arizona Diamondbacks bettors risk $100 to win $105 at +105 odds. The implied probability for Arizona Diamondbacks is 48.78%.
  • Philadelphia Phillies bettors risk $100 to win $80 at -125 odds. The implied probability for Philadelphia Phillies is 55.56%.

Philadelphia Phillies at Arizona Diamondbacks Prop Bets

MLB Prop Bets
+ Displays more odds
BetMGM Sports Betting BetMGM
Bet
Phillies
Diamondbacks
First Team to Score
9/21/25 4:10pm EDT
-190+145Bet
Phillies
Diamondbacks
Tie
1st Inning Winner
9/21/25 4:10pm EDT
+260+310-130Bet
Phillies
Diamondbacks
Tie
First 3 Innings Winner
9/21/25 4:10pm EDT
+125+154+310Bet
Phillies
Diamondbacks
To Extra Innings
9/21/25 4:10pm EDT
Yes +800No -1400Bet
BetMGM Sports Betting BetMGM
Phillies
Diamondbacks
1st Team to Score Will Win
9/21/25 4:10pm EDT
Yes -250No +190Bet
Diamondbacks
Total Runs
PHI at ARI
9/21/25 4:10pm EDT
4.5 o +1104.5 u -145Bet
Phillies
Total Runs
PHI at ARI
9/21/25 4:10pm EDT
4.5 o -1154.5 u -115Bet
Eduardo Rodriguez
Strikeouts Thrown
PHI at ARI
9/21/25 4:10pm EDT
4.5 o -1404.5 u +105Bet
BetMGM Sports Betting BetMGM
Ranger Suarez
Strikeouts Thrown
PHI at ARI
9/21/25 4:10pm EDT
4.5 o -1184.5 u -110Bet

Philadelphia Phillies & Arizona Diamondbacks Futures Odds

Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.

Philadelphia Phillies World Series Odds
2026 Philadelphia Phillies World Series Odds

Team
BetMGM Sports Betting BetMGM
Phillies
+1000
Bet
Arizona Diamondbacks World Series Odds
2026 Arizona Diamondbacks World Series Odds

Team
BetMGM Sports Betting BetMGM
Diamondbacks
+6000
Bet

Philadelphia Phillies & Arizona Diamondbacks Team Pages

Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Standings

2025 MLB Regular Season Standings - Philadelphia Phillies, Arizona Diamondbacks
Team W L Pct GB Home Away RS RA Diff Strk L10
x - Philadelphia Phillies96660.593+1.055-2641-40778648+130W15-5
e - Arizona Diamondbacks80820.494+17.043-3837-44791785+6L53-7

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Philadelphia Phillies vs Arizona Diamondbacks MLB Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Sunday, September 21st, 2025 at 4:10 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's MLB page, look for the Philadelphia Phillies vs Arizona Diamondbacks Game.

    Navigate to the sportsbook's MLB page. Next, look for live or upcoming matchups. Select the Philadelphia Phillies vs Arizona Diamondbacks Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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