Pittsburgh Pirates vs St. Louis Cardinals Odds

The Pirates will play the Cardinals on Wednesday, May 7th, 2025. Your timezone's first pitch time is 1:15 pm EDT. Check local listings or your nearest streaming app for coverage.

Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.


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Table of Contents

Key Matchup Stats

  • SportsBetting3.com Power Rankings - The Pittsburgh Pirates have a 84.67 power ranking. The power ranking for the St. Louis Cardinals is 91.00.
  • Visiting Pittsburgh Pirates - The Pittsburgh Pirates have a 5-12 record as a visiting team, ranking them 8th Overall for visiting team wins.
  • Home St. Louis Cardinals - The St. Louis Cardinals have a 13-6 record as a home team. They rank 3rd for home team wins in the Overall standings.
  • Runs Scored - The Pittsburgh Pirates currently stand 23rd (117) Overall, with the St. Louis Cardinals ranking 10th (167) for runs scored.
  • Runs Allowed - The Pittsburgh Pirates are 8th (168) Overall for runs allowed. The St. Louis Cardinals stand 9th (166) for runs allowed.
  • Team Streaks - The Pittsburgh Pirates have lost their last 5 games. Meanwhile, the St. Louis Cardinals have won their last 3 games.
  • Team Records - The Pittsburgh Pirates have a 12-24 Overall record (10.0 GB National Central Division), with the St. Louis Cardinals possessing a 17-19 Overall standing (5.0 GB National Central Division).

Captain Shady Lines

A broken compass is right at least twice a day.

Captain Shady Lines
Captain Shady Lines

Avast ye scurvy dogs! The Pittsburgh Pirates be setting sail for St. Louis...

This sorry excuse for a team be 12-24 overall, a disgraceful 0.333 win percentage...

The St. Louis Cardinals be ready to send these Pirates to Davy Jones' locker... (SportsBetting3.com)...bet on this game...review the odds below...

Best Pirates at Cardinals Odds


Best Moneyline Betting Odds
Underdog

Pittsburgh Pirates
Favorite

St. Louis Cardinals
The St. Louis Cardinals are the -175 moneyline favorite. Risk $175 to win $100 on the St. Louis Cardinals at BetMGM. The Pittsburgh Pirates are the +145 underdog at BetMGM. Risk $100 to win $145 on the Pittsburgh Pirates. Learn more about how to bet on money lines.

Best Total Betting Odds
OverUnder
BetMGM has the best over line of 7.5 runs. Risk $120 to win $100. BetMGM has the best under line of 7.5 runs. Risk $100 to win $100. Our tutorial explains more about total bets.

Best Run Line Betting Odds
Underdog

Pittsburgh Pirates
Favorite

St. Louis Cardinals
The St. Louis Cardinals have a -1.5 +125 run line at BetMGM OH. They are the run line favorite in this matchup. The Pittsburgh Pirates have a +1.5 -150 run line at BetMGM OH. The Pittsburgh Pirates are the run line underdogs. Review how to bet on a point spread with our text and video tutorials.

Matchup Odds FAQs

What is the moneyline for the Pittsburgh Pirates vs St. Louis Cardinals MLB game on Wednesday, May 7th, 2025?

The St. Louis Cardinals are the -175 moneyline favorite at BetMGM and the Pittsburgh Pirates are the +145 moneyline underdog at BetMGM.

What is the over-under total line for the Pittsburgh Pirates vs St. Louis Cardinals MLB game on Wednesday, May 7th, 2025?

The best over line is 7.5 -120 runs at BetMGM, which means you risk $120 to win $100 betting the over. The best under line is 7.5 +100 runs at BetMGM, and that means you risk $100 to win $100 betting the under.

What is the run line for the Pittsburgh Pirates vs St. Louis Cardinals MLB game on Wednesday, May 7th, 2025?

The St. Louis Cardinals are -1.5 +125 run line favorites at BetMGM, while the Pittsburgh Pirates are +1.5 -150 run line underdogs at BetMGM.

MLB Odds Example

MLB Odds and Outcomes Explained

Game
BetMGM Sports Betting BetMGM
Bet
Pirates
Cardinals
5/07/25 1:15pm EDT
+145-175
Bet $100 at BetMGM Ohio
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Possible Moneyline Outcomes
  • Pittsburgh Pirates bettors risk $100 to win $145 at +145 odds. The implied probability for Pittsburgh Pirates is 40.82%.
  • St. Louis Cardinals bettors risk $100 to win $57.14 at -175 odds. The implied probability for St. Louis Cardinals is 63.64%.

Pittsburgh Pirates at St. Louis Cardinals Prop Bets

MLB Prop Bets
+ Displays more odds
BetMGM Sports Betting BetMGM
Bet
Pirates
Cardinals
First Team to Score
5/07/25 1:15pm EDT
-120-105Bet
Pirates
Cardinals
Tie
1st Inning Winner
5/07/25 1:15pm EDT
+350+260-140Bet
Pirates
Cardinals
Tie
First 3 Innings Winner
5/07/25 1:15pm EDT
+185+110+280Bet
Pirates
Cardinals
To Extra Innings
5/07/25 1:15pm EDT
Yes +725No -1200Bet
BetMGM Sports Betting BetMGM
Pirates
Cardinals
1st Team to Score Will Win
5/07/25 1:15pm EDT
Yes -250No +190Bet
Pirates
Total Runs
PIT at STL
5/07/25 1:15pm EDT
3.5 o +1053.5 u -140Bet
Cardinals
Total Runs
PIT at STL
5/07/25 1:15pm EDT
4.5 o +1054.5 u -140Bet
Mitch Keller
Strikeouts Thrown
PIT at STL
5/07/25 1:15pm EDT
4.5 o +1254.5 u -165Bet
BetMGM Sports Betting BetMGM
Sonny Gray
Strikeouts Thrown
PIT at STL
5/07/25 1:15pm EDT
6.5 o +1006.5 u -130Bet

Pittsburgh Pirates & St. Louis Cardinals Futures Odds

Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.

Pittsburgh Pirates World Series Odds
2025 Pittsburgh Pirates World Series Odds

Team
BetMGM Sports Betting BetMGM
Pirates
+50000
Bet
St. Louis Cardinals World Series Odds
2025 St. Louis Cardinals World Series Odds

Team
BetMGM Sports Betting BetMGM
Cardinals
+6600
Bet

Pittsburgh Pirates & St. Louis Cardinals Team Pages

Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Standings

2025 MLB Regular Season Standings - Pittsburgh Pirates, St. Louis Cardinals
Team W L Pct GB Home Away RS RA Diff Strk L10
St. Louis Cardinals30240.556+5.019-811-16256216+40L16-4
Pittsburgh Pirates19360.345+16.513-166-20164236-72L24-6

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Pittsburgh Pirates vs St. Louis Cardinals MLB Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Wednesday, May 7th, 2025 at 1:15 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's MLB page, look for the Pittsburgh Pirates vs St. Louis Cardinals Game.

    Navigate to the sportsbook's MLB page. Next, look for live or upcoming matchups. Select the Pittsburgh Pirates vs St. Louis Cardinals Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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