The Pirates will play the Cardinals on Wednesday, May 20th, 2026. Your timezone's first pitch time is 7:45 pm EDT. Check local listings or your nearest streaming app for coverage.
Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.
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Table of Contents
- Matchup Stats
- Best Odds
- Interactive Odds Example
- Prop Bets
- Team Futures Odds
- Team Pages
- Team Standings
- Other Games Today
Key Matchup Stats
- SportsBetting3.com Power Rankings - The Pittsburgh Pirates have a 95.33 power ranking. The power ranking for the St. Louis Cardinals is 93.00.
- Visiting Pittsburgh Pirates - The Pittsburgh Pirates have a 5-5 record as a visiting team, ranking them 5th Overall for visiting team wins.
- Home St. Louis Cardinals - The St. Louis Cardinals have a 7-5 record as a home team. They rank 3rd for home team wins in the Overall standings.
- Runs Scored - The Pittsburgh Pirates currently stand 8th (114) Overall, with the St. Louis Cardinals ranking 9th (111) for runs scored.
- Runs Allowed - The Pittsburgh Pirates are 17th (93) Overall for runs allowed. The St. Louis Cardinals stand 5th (119) for runs allowed.
- Team Streaks - The Pittsburgh Pirates lost their last game. Meanwhile, the St. Louis Cardinals won their last game.
- Team Records - The Pittsburgh Pirates have a 13-10 Overall record (2.5 GB National Central Division), with the St. Louis Cardinals possessing a 14-9 Overall standing (1.5 GB National Central Division).
Best Pirates at Cardinals Odds
| Underdog Pittsburgh Pirates | Favorite St. Louis Cardinals |
|---|---|
| Over | Under |
|---|---|
| Underdog St. Louis Cardinals | Favorite Pittsburgh Pirates |
|---|---|
Matchup Odds FAQs
The St. Louis Cardinals are the -127 moneyline favorite at BetRivers and the Pittsburgh Pirates are the +102 moneyline underdog at BetRivers.
The best over line is 7.5 -121 runs at BetRivers, which means you risk $121 to win $100 betting the over. The best under line is 7.5 -104 runs at BetRivers, and that means you risk $104 to win $100 betting the under.
The Pittsburgh Pirates are -1.5 +175 run line favorites at BetRivers, while the St. Louis Cardinals are +1.5 -235 run line underdogs at BetRivers.
MLB Odds Example
|
Game |
 BetRiversBet |
|---|---|
Pirates
Cardinals
5/20/26 7:45pm EDT | +102-127 |
- Pittsburgh Pirates bettors risk $100 to win $102 at +102 odds. The implied probability for Pittsburgh Pirates is 49.5%.
- St. Louis Cardinals bettors risk $100 to win $78.74 at -127 odds. The implied probability for St. Louis Cardinals is 55.95%.
Pittsburgh Pirates at St. Louis Cardinals Prop Bets
| BetRivers Bet |
|
|---|---|
Pirates
Cardinals
Tie
1st Inning Winner
5/20/26 7:45pm EDT | +300+330-150Bet |
Pirates
Total Runs
PIT at STL 5/20/26 7:45pm EDT | 3.5 o -1243.5 u -103Bet |
Cardinals
Total Runs
PIT at STL 5/20/26 7:45pm EDT | 3.5 o -1363.5 u +106Bet |
Pittsburgh Pirates & St. Louis Cardinals Futures Odds
Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.
Pittsburgh Pirates World Series Odds|
Team |
|---|
| VA,US mlb Evnum: 1 Odds Pending |
|
Team |
|---|
| VA,US mlb Evnum: 1 Odds Pending |
Pittsburgh Pirates & St. Louis Cardinals Team Pages
Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:
Team Standings
| Team | W | L | Pct | GB | Home | Away | RS | RA | Diff | Strk | L10 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| St. Louis Cardinals | 61 | 61 | 0.500 | +14.0 | 32-34 | 29-27 | 529 | 533 | -4 | L1 | 6-4 |
| Pittsburgh Pirates | 59 | 64 | 0.480 | +16.5 | 30-30 | 29-34 | 617 | 592 | +25 | W1 | 3-7 |
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the Pittsburgh Pirates vs St. Louis Cardinals MLB Game
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Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Wednesday, May 20th, 2026 at 7:45 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
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Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
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Tap to the sportsbook's MLB page, look for the Pittsburgh Pirates vs St. Louis Cardinals Game.
Navigate to the sportsbook's MLB page. Next, look for live or upcoming matchups. Select the Pittsburgh Pirates vs St. Louis Cardinals Game.
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Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.
Other May 20, 2026 MLB Games
- Cincinnati Reds vs Philadelphia Phillies
- Baltimore Orioles vs Tampa Bay Rays
- Houston Astros vs Minnesota Twins
- Texas Rangers vs Colorado Rockies
- San Francisco Giants vs Arizona Diamondbacks
- Chicago White Sox vs Seattle Mariners
- Cleveland Guardians vs Detroit Tigers
- Atlanta Braves vs Miami Marlins
- New York Mets vs Washington Nationals
- Toronto Blue Jays vs New York Yankees
- Milwaukee Brewers vs Chicago Cubs
- Boston Red Sox vs Kansas City Royals
- Los Angeles Dodgers vs San Diego Padres
- Oakland Athletics vs Los Angeles Angels