The Pirates will play the Cardinals on Wednesday, May 20th, 2026. Your timezone's first pitch time is 7:45 pm EDT. Check local listings or your nearest streaming app for coverage.
Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.
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Table of Contents
- Matchup Stats
- Best Odds
- Interactive Odds Example
- Prop Bets
- Team Futures Odds
- Team Pages
- Team Standings
- Other Games Today
Key Matchup Stats
- SportsBetting3.com Power Rankings - The Pittsburgh Pirates have a 95.33 power ranking. The power ranking for the St. Louis Cardinals is 93.00.
- Visiting Pittsburgh Pirates - The Pittsburgh Pirates have a 5-5 record as a visiting team, ranking them 5th Overall for visiting team wins.
- Home St. Louis Cardinals - The St. Louis Cardinals have a 7-5 record as a home team. They rank 3rd for home team wins in the Overall standings.
- Runs Scored - The Pittsburgh Pirates currently stand 8th (114) Overall, with the St. Louis Cardinals ranking 9th (111) for runs scored.
- Runs Allowed - The Pittsburgh Pirates are 17th (93) Overall for runs allowed. The St. Louis Cardinals stand 5th (119) for runs allowed.
- Team Streaks - The Pittsburgh Pirates lost their last game. Meanwhile, the St. Louis Cardinals won their last game.
- Team Records - The Pittsburgh Pirates have a 13-10 Overall record (2.5 GB National Central Division), with the St. Louis Cardinals possessing a 14-9 Overall standing (1.5 GB National Central Division).
Best Pirates at Cardinals Odds
| Underdog Pittsburgh Pirates | Favorite St. Louis Cardinals |
|---|---|
| Over | Under |
|---|---|
| Underdog Pittsburgh Pirates | Favorite St. Louis Cardinals |
|---|---|
Matchup Odds FAQs
The St. Louis Cardinals are the -120 moneyline favorite at BetMGM and the Pittsburgh Pirates are the +100 moneyline underdog at BetMGM.
The best over line is 7.5 -115 runs at BetMGM, which means you risk $115 to win $100 betting the over. The best under line is 7.5 -105 runs at BetMGM, and that means you risk $105 to win $100 betting the under.
The St. Louis Cardinals are -1.5 +165 run line favorites at BetMGM, while the Pittsburgh Pirates are +1.5 -220 run line underdogs at BetMGM.
MLB Odds Example
|
Game |
 BetMGMBet |
|---|---|
Pirates
Cardinals
5/20/26 7:45pm EDT | +100-120 |
- Pittsburgh Pirates bettors risk $100 to win $100 at +100 odds. The implied probability for Pittsburgh Pirates is 50%.
- St. Louis Cardinals bettors risk $100 to win $83.33 at -120 odds. The implied probability for St. Louis Cardinals is 54.55%.
Pittsburgh Pirates at St. Louis Cardinals Prop Bets
| BetMGM Bet |
|
|---|---|
Pirates
Cardinals
5/20/26 7:45pm EDT | Pending BetMGM |
Pittsburgh Pirates & St. Louis Cardinals Futures Odds
Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.
Pittsburgh Pirates World Series Odds|
Team | BetMGM |
|---|---|
| Pirates | +5000 Bet |
|
Team | BetMGM |
|---|---|
| Cardinals | +12500 Bet |
Pittsburgh Pirates & St. Louis Cardinals Team Pages
Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:
Team Standings
| Team | W | L | Pct | GB | Home | Away | RS | RA | Diff | Strk | L10 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| St. Louis Cardinals | 14 | 9 | 0.609 | +2.0 | 7-5 | 7-4 | 111 | 119 | -8 | W1 | 6-4 |
| Pittsburgh Pirates | 13 | 10 | 0.565 | +3.0 | 8-5 | 5-5 | 114 | 93 | +21 | L1 | 5-5 |
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the Pittsburgh Pirates vs St. Louis Cardinals MLB Game
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Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Wednesday, May 20th, 2026 at 7:45 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
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Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
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Tap to the sportsbook's MLB page, look for the Pittsburgh Pirates vs St. Louis Cardinals Game.
Navigate to the sportsbook's MLB page. Next, look for live or upcoming matchups. Select the Pittsburgh Pirates vs St. Louis Cardinals Game.
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Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.
Other May 20, 2026 MLB Games
- Cincinnati Reds vs Philadelphia Phillies - 5/20/26 1:05pm EDT
- Baltimore Orioles vs Tampa Bay Rays - 5/20/26 1:10pm EDT
- Houston Astros vs Minnesota Twins - 5/20/26 1:40pm EDT
- Texas Rangers vs Colorado Rockies - 5/20/26 3:10pm EDT
- San Francisco Giants vs Arizona Diamondbacks - 5/20/26 3:40pm EDT
- Chicago White Sox vs Seattle Mariners - 5/20/26 4:10pm EDT
- Cleveland Guardians vs Detroit Tigers - 5/20/26 6:40pm EDT
- Atlanta Braves vs Miami Marlins - 5/20/26 6:40pm EDT
- New York Mets vs Washington Nationals - 5/20/26 6:45pm EDT
- Toronto Blue Jays vs New York Yankees - 5/20/26 7:05pm EDT
- Milwaukee Brewers vs Chicago Cubs - 5/20/26 7:40pm EDT
- Boston Red Sox vs Kansas City Royals - 5/20/26 7:40pm EDT
- Los Angeles Dodgers vs San Diego Padres - 5/20/26 8:40pm EDT
- Oakland Athletics vs Los Angeles Angels - 5/20/26 9:38pm EDT