The Pirates will play the Cardinals on Wednesday, May 7th, 2025. Your timezone's first pitch time is 1:15 pm EDT. Check local listings or your nearest streaming app for coverage.
Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.
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Table of Contents
- Matchup Stats
- Captain Shady Lines
- Best Odds
- Interactive Odds Example
- Prop Bets
- Team Futures Odds
- Team Pages
- Team Standings
- Other Games Today
Key Matchup Stats
- SportsBetting3.com Power Rankings - The Pittsburgh Pirates have a 84.67 power ranking. The power ranking for the St. Louis Cardinals is 91.00.
- Visiting Pittsburgh Pirates - The Pittsburgh Pirates have a 5-12 record as a visiting team, ranking them 8th Overall for visiting team wins.
- Home St. Louis Cardinals - The St. Louis Cardinals have a 13-6 record as a home team. They rank 3rd for home team wins in the Overall standings.
- Runs Scored - The Pittsburgh Pirates currently stand 23rd (117) Overall, with the St. Louis Cardinals ranking 10th (167) for runs scored.
- Runs Allowed - The Pittsburgh Pirates are 8th (168) Overall for runs allowed. The St. Louis Cardinals stand 9th (166) for runs allowed.
- Team Streaks - The Pittsburgh Pirates have lost their last 5 games. Meanwhile, the St. Louis Cardinals have won their last 3 games.
- Team Records - The Pittsburgh Pirates have a 12-24 Overall record (10.0 GB National Central Division), with the St. Louis Cardinals possessing a 17-19 Overall standing (5.0 GB National Central Division).
Captain Shady Lines
A broken compass is right at least twice a day.

Avast ye scurvy dogs! The Pittsburgh Pirates be setting sail for St. Louis...
This sorry excuse for a team be 12-24 overall, a disgraceful 0.333 win percentage...
The St. Louis Cardinals be ready to send these Pirates to Davy Jones' locker... (SportsBetting3.com)...bet on this game...review the odds below...
Best Pirates at Cardinals Odds
Underdog Pittsburgh Pirates | Favorite St. Louis Cardinals |
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Over | Under |
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Underdog Pittsburgh Pirates | Favorite St. Louis Cardinals |
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Matchup Odds FAQs
The St. Louis Cardinals are the -175 moneyline favorite at BetMGM and the Pittsburgh Pirates are the +145 moneyline underdog at BetMGM.
The best over line is 7.5 -120 runs at BetMGM, which means you risk $120 to win $100 betting the over. The best under line is 7.5 +100 runs at BetMGM, and that means you risk $100 to win $100 betting the under.
The St. Louis Cardinals are -1.5 +125 run line favorites at BetMGM, while the Pittsburgh Pirates are +1.5 -150 run line underdogs at BetMGM.
MLB Odds Example
Game |
![]() Bet |
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Pirates
Cardinals
5/07/25 1:15pm EDT | +145-175 |
- Pittsburgh Pirates bettors risk $100 to win $145 at +145 odds. The implied probability for Pittsburgh Pirates is 40.82%.
- St. Louis Cardinals bettors risk $100 to win $57.14 at -175 odds. The implied probability for St. Louis Cardinals is 63.64%.
Pittsburgh Pirates at St. Louis Cardinals Prop Bets
![]() Bet |
|
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Pirates
Cardinals
First Team to Score
5/07/25 1:15pm EDT | -120-105Bet |
Pirates
Cardinals
Tie
1st Inning Winner
5/07/25 1:15pm EDT | +350+260-140Bet |
Pirates
Cardinals
Tie
First 3 Innings Winner
5/07/25 1:15pm EDT | +185+110+280Bet |
Pirates
Cardinals
To Extra Innings
5/07/25 1:15pm EDT | Yes +725No -1200Bet |
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Pirates
Cardinals
1st Team to Score Will Win
5/07/25 1:15pm EDT | Yes -250No +190Bet |
Pirates
Total Runs
PIT at STL 5/07/25 1:15pm EDT | 3.5 o +1053.5 u -140Bet |
Cardinals
Total Runs
PIT at STL 5/07/25 1:15pm EDT | 4.5 o +1054.5 u -140Bet |
Mitch Keller
Strikeouts Thrown
PIT at STL 5/07/25 1:15pm EDT | 4.5 o +1254.5 u -165Bet |
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Sonny Gray
Strikeouts Thrown
PIT at STL 5/07/25 1:15pm EDT | 6.5 o +1006.5 u -130Bet |
Pittsburgh Pirates & St. Louis Cardinals Futures Odds
Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.
Pittsburgh Pirates World Series Odds
Team | ![]() |
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Pirates | +50000 Bet |
Team | ![]() |
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Cardinals | +6600 Bet |
Pittsburgh Pirates & St. Louis Cardinals Team Pages
Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:
Team Standings
Team | W | L | Pct | GB | Home | Away | RS | RA | Diff | Strk | L10 |
---|---|---|---|---|---|---|---|---|---|---|---|
St. Louis Cardinals | 30 | 24 | 0.556 | +5.0 | 19-8 | 11-16 | 256 | 216 | +40 | L1 | 6-4 |
Pittsburgh Pirates | 19 | 36 | 0.345 | +16.5 | 13-16 | 6-20 | 164 | 236 | -72 | L2 | 4-6 |
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the Pittsburgh Pirates vs St. Louis Cardinals MLB Game
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Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Wednesday, May 7th, 2025 at 1:15 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
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Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
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Tap to the sportsbook's MLB page, look for the Pittsburgh Pirates vs St. Louis Cardinals Game.
Navigate to the sportsbook's MLB page. Next, look for live or upcoming matchups. Select the Pittsburgh Pirates vs St. Louis Cardinals Game.
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Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.
Other May 7, 2025 MLB Games
- Cleveland Guardians vs Washington Nationals
- Houston Astros vs Milwaukee Brewers
- San Francisco Giants vs Chicago Cubs
- Seattle Mariners vs Oakland Athletics
- New York Mets vs Arizona Diamondbacks
- Los Angeles Dodgers vs Miami Marlins
- Texas Rangers vs Boston Red Sox
- San Diego Padres vs New York Yankees
- Philadelphia Phillies vs Tampa Bay Rays
- Cincinnati Reds vs Atlanta Braves
- Chicago White Sox vs Kansas City Royals
- Baltimore Orioles vs Minnesota Twins
- Detroit Tigers vs Colorado Rockies
- Toronto Blue Jays vs Los Angeles Angels