The Padres will play the Astros on Sunday, April 20th, 2025. Your timezone's first pitch time is 7:10 pm EDT. Check local listings or your nearest streaming app for coverage.

Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.

STATE	Bonus

Matchup Stats
Captain Shady Lines
Best Odds
Interactive Odds Example
Prop Bets
Team Futures Odds
Team Pages
Team Standings
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Key Matchup Stats

SportsBetting3.com Power Rankings - The San Diego Padres have a 98.00 power ranking. The power ranking for the Houston Astros is 92.33.
Visiting San Diego Padres - The San Diego Padres have a 3-4 record as a visiting team, ranking them 7th Overall for visiting team wins.
Home Houston Astros - The Houston Astros have a 5-5 record as a home team. They rank 7th for home team wins in the Overall standings.
Runs Scored - The San Diego Padres currently stand 9th (92) Overall, with the Houston Astros ranking 20th (72) for runs scored.
Runs Allowed - The San Diego Padres are 18th (57) Overall for runs allowed. The Houston Astros stand 15th (74) for runs allowed.
Team Streaks - The San Diego Padres lost their last game. Meanwhile, the Houston Astros won their last game.
Team Records - The San Diego Padres have a 15-5 Overall record (0.0 GB National West Division), with the Houston Astros possessing a 9-10 Overall standing (2.5 GB American West Division).

Captain Shady Lines

A broken compass is right at least twice a day.

Arrgh, ye scallywags! The Padres be plundering the Astros on Sunday!

San Diego sets sail with a record that be striking fear in Houston...

With a 0.750 win percentage, the Padres be leavin' opponents walkin' the plank...

SportsBetting3.com be where ye can bet on this game, so review the odds below!

Best Padres at Astros Odds

**Best Moneyline Betting Odds**
TBD	TBD

Moneyline odds are updating, please check back soon.

**Best Total Betting Odds**
Over	Under

Total odds are updating, please check back soon.

**Best Run Line Betting Odds**
TBD	TBD

Run Line odds are updating, please check back soon.

MLB Odds Example

MLB Odds and Outcomes Explained
Game	Book

San Diego Padres at Houston Astros Prop Bets

MLB Prop Bets
+ Displays more odds
	Bet
Padres Astros 4/20/25 7:10pm EDT	Pending

San Diego Padres & Houston Astros Futures Odds

Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.

San Diego Padres World Series Odds

No World Series TM San Diego Padres YR: futures available

Houston Astros World Series Odds

No World Series TM Houston Astros YR: futures available

San Diego Padres & Houston Astros Team Pages

Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Standings

2025 MLB Regular Season Standings - San Diego Padres, Houston Astros
Team	W	L	Pct	GB	Home	Away	RS	RA	Diff	Strk	L10
y - San Diego Padres	90	72	0.556	+7.0	52-29	38-43	702	621	+81	W3	7-3
e - Houston Astros	87	75	0.537	+10.0	46-35	41-40	686	665	+21	W2	4-6

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the San Diego Padres vs Houston Astros MLB Game

Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Sunday, April 20th, 2025 at 7:10 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
Tap to the sportsbook's MLB page, look for the San Diego Padres vs Houston Astros Game.
Navigate to the sportsbook's MLB page. Next, look for live or upcoming matchups. Select the San Diego Padres vs Houston Astros Game.
Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

Other April 20, 2025 MLB Games

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San Diego Padres vs Houston Astros Odds

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