The Padres will play the Cardinals on Sunday, July 27th, 2025. Your timezone's first pitch time is 2:15 pm EDT. Check local listings or your nearest streaming app for coverage.
Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.
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Table of Contents
- Best Odds
- Interactive Odds Example
- Prop Bets
- Team Futures Odds
- Team Pages
- Team Standings
- Other Games Today
Best Padres at Cardinals Odds
| Underdog San Diego Padres | Favorite St. Louis Cardinals |
|---|---|
| Over | Under |
|---|---|
| Underdog St. Louis Cardinals | Favorite San Diego Padres |
|---|---|
Matchup Odds FAQs
The St. Louis Cardinals are the -125 moneyline favorite at BetMGM and the San Diego Padres are the +105 moneyline underdog at BetMGM.
The best over line is 9 +100 runs at BetMGM, which means you risk $100 to win $100 betting the over. The best under line is 9 -120 runs at BetMGM, and that means you risk $120 to win $100 betting the under.
The San Diego Padres are -1.5 +160 run line favorites at BetMGM, while the St. Louis Cardinals are +1.5 -210 run line underdogs at BetMGM.
MLB Odds Example
|
Game |
 BetMGMBet |
|---|---|
Padres
Cardinals
7/27/25 2:15pm EDT | +105-125 |
- San Diego Padres bettors risk $100 to win $105 at +105 odds. The implied probability for San Diego Padres is 48.78%.
- St. Louis Cardinals bettors risk $100 to win $80 at -125 odds. The implied probability for St. Louis Cardinals is 55.56%.
San Diego Padres at St. Louis Cardinals Prop Bets
| BetMGM Bet |
|
|---|---|
Padres
Cardinals
First Team to Score
7/27/25 2:15pm EDT | -150+115Bet |
Padres
Cardinals
Tie
1st Inning Winner
7/27/25 2:15pm EDT | +290+260-120Bet |
Padres
Cardinals
Tie
First 3 Innings Winner
7/27/25 2:15pm EDT | +145+125+325Bet |
Padres
Cardinals
To Extra Innings
7/27/25 2:15pm EDT | Yes +775No -1400Bet |
| BetMGM | |
Padres
Cardinals
1st Team to Score Will Win
7/27/25 2:15pm EDT | Yes -250No +190Bet |
Padres
Total Runs
SDG at STL 7/27/25 2:15pm EDT | 4.5 o +1054.5 u -140Bet |
Cardinals
Total Runs
SDG at STL 7/27/25 2:15pm EDT | 4.5 o -1024.5 u -130Bet |
Michael McGreevy
Strikeouts Thrown
SDG at STL 7/27/25 2:15pm EDT | 2.5 o -1602.5 u +125Bet |
| BetMGM | |
Stephen Kolek
Strikeouts Thrown
SDG at STL 7/27/25 2:15pm EDT | 3.5 o +1353.5 u -175Bet |
San Diego Padres & St. Louis Cardinals Futures Odds
Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.
San Diego Padres World Series Odds|
Team | BetMGM |
|---|---|
| Padres | +1000 Bet |
|
Team | BetMGM |
|---|---|
| Cardinals | +100000 Bet |
San Diego Padres & St. Louis Cardinals Team Pages
Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:
Team Standings
| Team | W | L | Pct | GB | Home | Away | RS | RA | Diff | Strk | L10 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| San Diego Padres | 75 | 59 | 0.560 | +7.5 | 43-22 | 32-37 | 564 | 510 | +54 | L1 | 6-4 |
| St. Louis Cardinals | 66 | 69 | 0.489 | +17.0 | 37-32 | 29-37 | 588 | 622 | -34 | W1 | 5-5 |
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the San Diego Padres vs St. Louis Cardinals MLB Game
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Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Sunday, July 27th, 2025 at 2:15 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
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Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
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Tap to the sportsbook's MLB page, look for the San Diego Padres vs St. Louis Cardinals Game.
Navigate to the sportsbook's MLB page. Next, look for live or upcoming matchups. Select the San Diego Padres vs St. Louis Cardinals Game.
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Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.
Other July 27, 2025 MLB Games
- Arizona Diamondbacks vs Pittsburgh Pirates
- Colorado Rockies vs Baltimore Orioles
- Philadelphia Phillies vs New York Yankees
- Tampa Bay Rays vs Cincinnati Reds
- Toronto Blue Jays vs Detroit Tigers
- Los Angeles Dodgers vs Boston Red Sox
- Chicago Cubs vs Chicago White Sox
- Miami Marlins vs Milwaukee Brewers
- Cleveland Guardians vs Kansas City Royals
- Oakland Athletics vs Houston Astros
- Washington Nationals vs Minnesota Twins
- Atlanta Braves vs Texas Rangers
- Seattle Mariners vs Los Angeles Angels
- New York Mets vs San Francisco Giants