The Giants will play the Diamondbacks on Monday, September 15th, 2025. Your timezone's first pitch time is 9:40 pm EDT. Check local listings or your nearest streaming app for coverage.
Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.
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Table of Contents
- Best Odds
- Interactive Odds Example
- Prop Bets
- Team Futures Odds
- Team Pages
- Team Standings
- Other Games Today
Best Giants at Diamondbacks Odds
| Underdog San Francisco Giants | Favorite Arizona Diamondbacks |
|---|---|
| Over | Under |
|---|---|
| Underdog San Francisco Giants | Favorite Arizona Diamondbacks |
|---|---|
Matchup Odds FAQs
The Arizona Diamondbacks are the -145 moneyline favorite at BetMGM and the San Francisco Giants are the +120 moneyline underdog at BetMGM.
The best over line is 9 -120 runs at BetMGM, which means you risk $120 to win $100 betting the over. The best under line is 9 +100 runs at BetMGM, and that means you risk $100 to win $100 betting the under.
The Arizona Diamondbacks are -1.5 +145 run line favorites at BetMGM, while the San Francisco Giants are +1.5 -175 run line underdogs at BetMGM.
MLB Odds Example
|
Game |
 BetMGMBet |
|---|---|
Giants
Diamondbacks
9:40pm EDT | +120-145 |
- San Francisco Giants bettors risk $100 to win $120 at +120 odds. The implied probability for San Francisco Giants is 45.45%.
- Arizona Diamondbacks bettors risk $100 to win $68.97 at -145 odds. The implied probability for Arizona Diamondbacks is 59.18%.
San Francisco Giants at Arizona Diamondbacks Prop Bets
| BetMGM Bet |
|
|---|---|
Giants
Diamondbacks
9:40pm EDT | Pending BetMGM |
San Francisco Giants & Arizona Diamondbacks Futures Odds
Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.
San Francisco Giants World Series Odds|
Team | BetMGM |
|---|---|
| Giants | +6000 Bet |
|
Team | BetMGM |
|---|---|
| Diamondbacks | +50000 Bet |
San Francisco Giants & Arizona Diamondbacks Team Pages
Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:
Team Standings
| Team | W | L | Pct | GB | Home | Away | RS | RA | Diff | Strk | L10 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| San Francisco Giants | 75 | 74 | 0.503 | +15.5 | 38-37 | 37-37 | 651 | 629 | +22 | L2 | 5-5 |
| Arizona Diamondbacks | 75 | 75 | 0.500 | +16.0 | 38-34 | 37-41 | 743 | 720 | +23 | W2 | 6-4 |
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the San Francisco Giants vs Arizona Diamondbacks MLB Game
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Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Monday, September 15th, 2025 at 9:40 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
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Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
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Tap to the sportsbook's MLB page, look for the San Francisco Giants vs Arizona Diamondbacks Game.
Navigate to the sportsbook's MLB page. Next, look for live or upcoming matchups. Select the San Francisco Giants vs Arizona Diamondbacks Game.
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Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.
Other September 15, 2025 MLB Games
- Chicago Cubs vs Pittsburgh Pirates - 6:40pm EDT
- Atlanta Braves vs Washington Nationals - 6:45pm EDT
- Toronto Blue Jays vs Tampa Bay Rays - 7:35pm EDT
- Baltimore Orioles vs Chicago White Sox - 7:40pm EDT
- New York Yankees vs Minnesota Twins - 7:40pm EDT
- Cincinnati Reds vs St. Louis Cardinals - 7:45pm EDT
- Texas Rangers vs Houston Astros - 8:10pm EDT
- Philadelphia Phillies vs Los Angeles Dodgers - 10:10pm EDT