The Giants will play the Cubs on Wednesday, May 7th, 2025. Your timezone's first pitch time is 2:20 pm EDT. Check local listings or your nearest streaming app for coverage.
Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.
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Table of Contents
- Matchup Stats
- Captain Shady Lines
- Best Odds
- Interactive Odds Example
- Prop Bets
- Team Futures Odds
- Team Pages
- Team Standings
- Other Games Today
Key Matchup Stats
- SportsBetting3.com Power Rankings - The San Francisco Giants have a 95.00 power ranking. The power ranking for the Chicago Cubs is 97.67.
- Visiting San Francisco Giants - The San Francisco Giants have a 10-9 record as a visiting team, ranking them 3rd Overall for visiting team wins.
- Home Chicago Cubs - The Chicago Cubs have a 10-7 record as a home team. They rank 6th for home team wins in the Overall standings.
- Runs Scored - The San Francisco Giants currently stand 11th (166) Overall, with the Chicago Cubs ranking 1st (217) for runs scored.
- Runs Allowed - The San Francisco Giants are 20th (138) Overall for runs allowed. The Chicago Cubs stand 15th (148) for runs allowed.
- Team Streaks - The San Francisco Giants lost their last game. Meanwhile, the Chicago Cubs won their last game.
- Team Records - The San Francisco Giants have a 22-14 Overall record (2.5 GB National West Division), with the Chicago Cubs possessing a 22-14 Overall standing (0.0 GB National Central Division).
Captain Shady Lines
A broken compass is right at least twice a day.
Avast ye scallywags! The Giants be facin' the Cubs in Chicago, arrr!
Both teams be boastin' a 22-14 record, tied like two barnacles on a ship...
Ye better bet on this game, me hearties, and review the odds below!
The Giants be needin' to improve their last 10 games record to plunder victory...
But beware, the Cubs be havin' the home field advantage and a winnin' streak!
Come Wednesday, May 7th, the battle on the diamond will be fierce, arrr!
Best Giants at Cubs Odds
| Underdog San Francisco Giants | Favorite Chicago Cubs |
|---|---|
| Over | Under |
|---|---|
| Underdog San Francisco Giants | Favorite Chicago Cubs |
|---|---|
Matchup Odds FAQs
The Chicago Cubs are the -160 moneyline favorite at BetMGM and the San Francisco Giants are the +140 moneyline underdog at BetRivers.
The best over line is 7.5 -102 runs at BetMGM, which means you risk $102 to win $100 betting the over. The best under line is 7.5 -112 runs at BetRivers, and that means you risk $112 to win $100 betting the under.
The Chicago Cubs are -1.5 +145 run line favorites at BetMGM, while the San Francisco Giants are +1.5 -165 run line underdogs at BetRivers.
MLB Odds Example
|
Game |
 BetMGMBet |
|---|---|
Giants
Cubs
5/07/25 2:20pm EDT | +135-160 |
- San Francisco Giants bettors risk $100 to win $135 at +135 odds. The implied probability for San Francisco Giants is 42.55%.
- Chicago Cubs bettors risk $100 to win $62.5 at -160 odds. The implied probability for Chicago Cubs is 61.54%.
San Francisco Giants at Chicago Cubs Prop Bets
| BetMGM Bet |
|
|---|---|
Giants
Cubs
First Team to Score
5/07/25 2:20pm EDT | -120-105Bet |
Giants
Cubs
Tie
1st Inning Winner
5/07/25 2:20pm EDT | +375+290-160Bet |
Giants
Cubs
Tie
First 3 Innings Winner
5/07/25 2:20pm EDT | +195+115+240Bet |
Giants
Cubs
To Extra Innings
5/07/25 2:20pm EDT | Yes +700No -1100Bet |
| BetMGM | |
Giants
Cubs
1st Team to Score Will Win
5/07/25 2:20pm EDT | Yes -250No +190Bet |
Cubs
Total Runs
SFO at CUB 5/07/25 2:20pm EDT | 3.5 o -1453.5 u +110Bet |
Giants
Total Runs
SFO at CUB 5/07/25 2:20pm EDT | 3.5 o +1053.5 u -140Bet |
Ben Brown
Strikeouts Thrown
SFO at CUB 5/07/25 2:20pm EDT | 5.5 o -1205.5 u -110Bet |
| BetMGM | |
Robbie Ray
Strikeouts Thrown
SFO at CUB 5/07/25 2:20pm EDT | 5.5 o +1055.5 u -135Bet |
San Francisco Giants & Chicago Cubs Futures Odds
Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.
San Francisco Giants World Series Odds|
Team | BetMGM |
 BetRivers |
|---|---|---|
| Giants | +4000 Bet | +5000 Bet |
|
Team | BetMGM |
BetRivers |
|---|---|---|
| Cubs | +1600 Bet | +1500 Bet |
San Francisco Giants & Chicago Cubs Team Pages
Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:
Team Standings
| Team | W | L | Pct | GB | Home | Away | RS | RA | Diff | Strk | L10 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Chicago Cubs | 25 | 19 | 0.568 | +4.0 | 12-10 | 13-9 | 244 | 192 | +52 | L1 | 4-6 |
| San Francisco Giants | 25 | 19 | 0.568 | +4.0 | 13-7 | 12-12 | 209 | 172 | +37 | L1 | 4-6 |
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the San Francisco Giants vs Chicago Cubs MLB Game
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Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Wednesday, May 7th, 2025 at 2:20 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
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Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
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Tap to the sportsbook's MLB page, look for the San Francisco Giants vs Chicago Cubs Game.
Navigate to the sportsbook's MLB page. Next, look for live or upcoming matchups. Select the San Francisco Giants vs Chicago Cubs Game.
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Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.
Other May 7, 2025 MLB Games
- Cleveland Guardians vs Washington Nationals - 5/07/25 12:05pm EDT
- Houston Astros vs Milwaukee Brewers - 5/07/25 1:10pm EDT
- Pittsburgh Pirates vs St. Louis Cardinals - 5/07/25 1:15pm EDT
- Seattle Mariners vs Oakland Athletics - 5/07/25 3:35pm EDT
- New York Mets vs Arizona Diamondbacks - 5/07/25 3:40pm EDT
- Los Angeles Dodgers vs Miami Marlins - 5/07/25 4:40pm EDT
- Texas Rangers vs Boston Red Sox - 5/07/25 6:45pm EDT
- San Diego Padres vs New York Yankees - 5/07/25 7:05pm EDT
- Philadelphia Phillies vs Tampa Bay Rays - 5/07/25 7:05pm EDT
- Cincinnati Reds vs Atlanta Braves - 5/07/25 7:15pm EDT
- Chicago White Sox vs Kansas City Royals - 5/07/25 7:40pm EDT
- Baltimore Orioles vs Minnesota Twins - 5/07/25 7:40pm EDT
- Detroit Tigers vs Colorado Rockies - 5/07/25 8:40pm EDT
- Toronto Blue Jays vs Los Angeles Angels - 5/07/25 9:38pm EDT