The Giants will play the Guardians on Wednesday, March 12th, 2025. Your timezone's first pitch time is 4:05 pm EDT. Check local listings or your nearest streaming app for coverage.

Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.

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Best Giants at Guardians Odds

**Best Moneyline Betting Odds**
TBD	TBD

Moneyline odds are updating, please check back soon.

**Best Total Betting Odds**
Over	Under

Total odds are updating, please check back soon.

**Best Run Line Betting Odds**
TBD	TBD

Run Line odds are updating, please check back soon.

MLB Odds Example

MLB Odds and Outcomes Explained
Game	Book

San Francisco Giants at Cleveland Guardians Prop Bets

MLB Prop Bets
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	BetMGM Bet
Giants Guardians 3/12/25 4:05pm EDT	Pending BetMGM

San Francisco Giants & Cleveland Guardians Futures Odds

Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.

San Francisco Giants World Series Odds

2025 San Francisco Giants World Series Odds
Team	BetMGM
Giants	+2800 Bet

Cleveland Guardians World Series Odds

2025 Cleveland Guardians World Series Odds
Team	BetMGM
Guardians	+10000 Bet

San Francisco Giants & Cleveland Guardians Team Pages

Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Standings

2025 MLB Regular Season Standings - San Francisco Giants, Cleveland Guardians
Team	W	L	Pct	GB	Home	Away	RS	RA	Diff	Strk	L10
San Francisco Giants	31	24	0.564	+4.5	17-9	14-15	239	199	+40	L2	5-5
Cleveland Guardians	29	25	0.537	+6.0	14-10	15-15	216	236	-20	L3	4-6

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the San Francisco Giants vs Cleveland Guardians MLB Game

Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Wednesday, March 12th, 2025 at 4:05 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
Tap to the sportsbook's MLB page, look for the San Francisco Giants vs Cleveland Guardians Game.
Navigate to the sportsbook's MLB page. Next, look for live or upcoming matchups. Select the San Francisco Giants vs Cleveland Guardians Game.
Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

Other March 12, 2025 MLB Games

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San Francisco Giants vs Cleveland Guardians Odds

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