Tampa Bay Rays vs Cleveland Guardians Odds

The Rays will play the Guardians on Wednesday, April 29th, 2026. Your timezone's first pitch time is 1:30 pm EDT. Check local listings or your nearest streaming app for coverage.

Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.


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Table of Contents

Key Matchup Stats

  • SportsBetting3.com Power Rankings - The Tampa Bay Rays have a 89.00 power ranking. The power ranking for the Cleveland Guardians is 93.00.
  • Visiting Tampa Bay Rays - The Tampa Bay Rays have a 8-7 record as a visiting team, ranking them 2nd Overall for visiting team wins.
  • Home Cleveland Guardians - The Cleveland Guardians have a 8-4 record as a home team. They rank 2nd for home team wins in the Overall standings.
  • Runs Scored - The Tampa Bay Rays currently stand 10th (110) Overall, with the Cleveland Guardians ranking 12th (105) for runs scored.
  • Runs Allowed - The Tampa Bay Rays are 3rd (127) Overall for runs allowed. The Cleveland Guardians stand 11th (109) for runs allowed.
  • Team Streaks - The Tampa Bay Rays have lost their last 3 games. Meanwhile, the Cleveland Guardians won their last game.
  • Team Records - The Tampa Bay Rays have a 12-11 Overall record (2.0 GB American East Division), with the Cleveland Guardians possessing a 14-11 Overall standing (0.0 GB American Central Division).

Captain Shady Lines

A broken compass is right at least twice a day.

Captain Shady Lines
Captain Shady Lines

Avast ye scurvy dogs! The Rays be takin' on the Guardians in Cleveland...

Tampa Bay be comin' in with a record just barely above water...

If ye be lookin' to make some doubloons, head on over to SportsBetting3.com... (bet on this game) ...and review the odds below. May the best team plunder the victory!

Best Rays at Guardians Odds


Best Moneyline Betting Odds
Underdog

Tampa Bay Rays
Favorite

Cleveland Guardians
The Cleveland Guardians are the -115 moneyline favorite. Risk $115 to win $100 on the Cleveland Guardians at BetMGM. The Tampa Bay Rays are the -105 underdog at BetMGM. Risk $105 to win $100 on the Tampa Bay Rays. Learn more about how to bet on money lines.

Best Total Betting Odds
OverUnder
BetMGM has the best over line of 6.5 runs. Risk $110 to win $100. BetMGM has the best under line of 6.5 runs. Risk $110 to win $100. Our tutorial explains more about total bets.

Best Run Line Betting Odds
Underdog

Cleveland Guardians
Favorite

Tampa Bay Rays
The Tampa Bay Rays have a -1.5 +170 run line at BetMGM OH. They are the run line favorite in this matchup. The Cleveland Guardians have a +1.5 -210 run line at BetMGM OH. The Cleveland Guardians are the run line underdogs. Review how to bet on a point spread with our text and video tutorials.

Matchup Odds FAQs

What is the moneyline for the Tampa Bay Rays vs Cleveland Guardians MLB game on Wednesday, April 29th, 2026?

The Cleveland Guardians are the -115 moneyline favorite at BetMGM and the Tampa Bay Rays are the -105 moneyline underdog at BetMGM.

What is the over-under total line for the Tampa Bay Rays vs Cleveland Guardians MLB game on Wednesday, April 29th, 2026?

The best over line is 6.5 -110 runs at BetMGM, which means you risk $110 to win $100 betting the over. The best under line is 6.5 -110 runs at BetMGM, and that means you risk $110 to win $100 betting the under.

What is the run line for the Tampa Bay Rays vs Cleveland Guardians MLB game on Wednesday, April 29th, 2026?

The Tampa Bay Rays are -1.5 +170 run line favorites at BetMGM, while the Cleveland Guardians are +1.5 -210 run line underdogs at BetMGM.

MLB Odds Example

MLB Odds and Outcomes Explained

Game
BetMGM Sports Betting BetMGM
Bet
Rays
Guardians
4/29/26 1:30pm EDT
-105-115
Bet $100 at BetMGM Ohio
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Possible Moneyline Outcomes
  • Tampa Bay Rays bettors risk $100 to win $95.24 at -105 odds. The implied probability for Tampa Bay Rays is 51.22%.
  • Cleveland Guardians bettors risk $100 to win $86.96 at -115 odds. The implied probability for Cleveland Guardians is 53.49%.

Tampa Bay Rays at Cleveland Guardians Prop Bets

MLB Prop Bets
+ Displays more odds
BetMGM Sports Betting BetMGM
Bet
Rays
Guardians
First Team to Score
4/29/26 1:30pm EDT
-150+115Bet
Rays
Guardians
Tie
1st Inning Winner
4/29/26 1:30pm EDT
+350+375-185Bet
Rays
Guardians
Tie
First 3 Innings Winner
4/29/26 1:30pm EDT
+160+165+210Bet
Rays
Guardians
To Extra Innings
4/29/26 1:30pm EDT
Yes +600No -900Bet
BetMGM Sports Betting BetMGM
Rays
Guardians
1st Team to Score Will Win
4/29/26 1:30pm EDT
Yes -250No +190Bet
Guardians
Total Runs
TAM at CLE
4/29/26 1:30pm EDT
3.5 o +1203.5 u -155Bet
Rays
Total Runs
TAM at CLE
4/29/26 1:30pm EDT
3.5 o +1103.5 u -145Bet

Tampa Bay Rays & Cleveland Guardians Futures Odds

Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.

Tampa Bay Rays World Series Odds
2026 Tampa Bay Rays World Series Odds

Team
BetMGM Sports Betting BetMGM
Rays
+3500
Bet
Cleveland Guardians World Series Odds
2026 Cleveland Guardians World Series Odds

Team
BetMGM Sports Betting BetMGM
Guardians
+4500
Bet

Tampa Bay Rays & Cleveland Guardians Team Pages

Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Standings

2026 MLB Regular Season Standings - Tampa Bay Rays, Cleveland Guardians
Team W L Pct GB Home Away RS RA Diff Strk L10
Cleveland Guardians14110.560+3.08-46-7105109-4W15-5
Tampa Bay Rays12110.522+4.04-48-7110127-17L36-4

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Tampa Bay Rays vs Cleveland Guardians MLB Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Wednesday, April 29th, 2026 at 1:30 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's MLB page, look for the Tampa Bay Rays vs Cleveland Guardians Game.

    Navigate to the sportsbook's MLB page. Next, look for live or upcoming matchups. Select the Tampa Bay Rays vs Cleveland Guardians Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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