Washington Nationals vs Houston Astros Odds

The Nationals will play the Astros on Thursday, March 12th, 2026. Your timezone's first pitch time is 6:05 pm EDT. Check local listings or your nearest streaming app for coverage.

Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.


Bonus
BetRivers Sportsbook#1 BetRivers
REVIEW
New Customers - 2nd Chance Bet up to $500 - Code: SPORTS
Bet Now
21+ Playable in PA only
Gambling Problem? Call 1-800-GAMBLER

Table of Contents

Best Nationals at Astros Odds


Best Moneyline Betting Odds
Underdog

Washington Nationals
Favorite

Houston Astros
The Houston Astros are the -159 moneyline favorite. Risk $159 to win $100 on the Houston Astros at BetRivers. The Washington Nationals are the +116 underdog at BetRivers. Risk $100 to win $116 on the Washington Nationals. Learn more about how to bet on money lines.

Best Total Betting Odds
OverUnder
BetRivers has the best over line of 10.5 runs. Risk $125 to win $100. BetRivers has the best under line of 10.5 runs. Risk $108 to win $100. Our tutorial explains more about total bets.

Best Run Line Betting Odds
Underdog

Washington Nationals
Favorite

Houston Astros
The Houston Astros have a -1.5 +132 run line at BetRivers PA. They are the run line favorite in this matchup. The Washington Nationals have a +1.5 -182 run line at BetRivers PA. The Washington Nationals are the run line underdogs. Review how to bet on a point spread with our text and video tutorials.

Matchup Odds FAQs

What is the moneyline for the Washington Nationals vs Houston Astros MLB game on Thursday, March 12th, 2026?

The Houston Astros are the -159 moneyline favorite at BetRivers and the Washington Nationals are the +116 moneyline underdog at BetRivers.

What is the over-under total line for the Washington Nationals vs Houston Astros MLB game on Thursday, March 12th, 2026?

The best over line is 10.5 -125 runs at BetRivers, which means you risk $125 to win $100 betting the over. The best under line is 10.5 -108 runs at BetRivers, and that means you risk $108 to win $100 betting the under.

What is the run line for the Washington Nationals vs Houston Astros MLB game on Thursday, March 12th, 2026?

The Houston Astros are -1.5 +132 run line favorites at BetRivers, while the Washington Nationals are +1.5 -182 run line underdogs at BetRivers.

MLB Odds Example

MLB Odds and Outcomes Explained

Game
BetRivers Sports Betting BetRivers
Bet
Nationals
Astros
3/12/26 6:05pm EDT
+116-159
Bet $100 at BetRivers Pennsylvania
21+ Playable in PA only
Gambling Problem? Call 1-800-GAMBLER
Possible Moneyline Outcomes
  • Washington Nationals bettors risk $100 to win $116 at +116 odds. The implied probability for Washington Nationals is 46.3%.
  • Houston Astros bettors risk $100 to win $62.89 at -159 odds. The implied probability for Houston Astros is 61.39%.

Washington Nationals at Houston Astros Prop Bets

MLB Prop Bets
+ Displays more odds
BetRivers Sports Betting BetRivers
Bet
Nationals
Astros
3/12/26 6:05pm EDT
Pending BetRivers

Washington Nationals & Houston Astros Futures Odds

Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.

Washington Nationals World Series Odds
2026 Washington Nationals World Series Odds

Team
VA,US mlb Evnum: 1 Odds Pending
Houston Astros World Series Odds
2026 Houston Astros World Series Odds

Team
VA,US mlb Evnum: 1 Odds Pending

Washington Nationals & Houston Astros Team Pages

Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Standings

2026 MLB Regular Season Standings - Washington Nationals, Houston Astros
Team W L Pct GB Home Away RS RA Diff Strk L10
Houston Astros59570.509+13.530-2929-28540565-25L17-3
Washington Nationals56610.479+17.023-3433-27623613+10L12-8

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Washington Nationals vs Houston Astros MLB Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Thursday, March 12th, 2026 at 6:05 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's MLB page, look for the Washington Nationals vs Houston Astros Game.

    Navigate to the sportsbook's MLB page. Next, look for live or upcoming matchups. Select the Washington Nationals vs Houston Astros Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

Other March 12, 2026 MLB Games

Odds Preview 14775