The Sixers will play the Celtics on Wednesday, October 22nd, 2025. Your timezone's tip off time is 7:30 pm EDT. Check local listings or your nearest streaming app for coverage.
Learn more about NBA Betting with our handy tutorial and guide. We explain spread, total and money line bets. Plus, a great discussion about exotic bets like NBA parlays and props.
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Table of Contents
- Matchup Stats
- Captain Shady Lines
- Best Odds
- Interactive Odds Example
- Prop Bets
- Team Standings
- Futures Odds
- Team Pages
- Other Games Today
Key Matchup Stats
The 2025-26 NBA regular season has just tipped off for the Philadelphia 76ers and Boston Celtics. Let's check on some stats from 2024-25 to get a sense of what to expect for this matchup on Wednesday, October 22nd, 2025. It's also a great way to mark a starting point for each team's performance for this upcoming season.
- SportsBetting3.com Power Rankings - The Philadelphia 76ers had a 84.67 power ranking in the 2024-25 NBA regular season. The power ranking for the Boston Celtics in the 2024-25 regular season was 97.67.
- Away Philadelphia 76ers - At the end of the 2024-25 NBA regular season, the Philadelphia 76ers had a 12-29 record as an away team, ranking them 13th in the regular season for away team wins.
- Home Boston Celtics - The Boston Celtics finished the 2024-25 regular season with a 28-13 record as a home team. They ranked 6th for home team wins in the regular season standings.
- Average Points Per Game - At the end of the 2024-25 regular season, the Philadelphia 76ers ranked 23rd (109.6) for average points scored per game, with the Boston Celtics winding up 8th (116.3).
- Average Opponent Points Per Game - As for the average number of points scored by opponents in the 2024-25 regular season, the Philadelphia 76ers finished 8th (115.8), with the Boston Celtics ranked 26th (107.2).
- Team Records - The Philadelphia 76ers had a 24-58 record for 2024-25, with the Boston Celtics finishing the regular season with a 61-21 standing.
Captain Shady Lines
A broken compass is right at least twice a day.
Avast ye, mateys! The Philadelphia 76ers be takin' on the Boston Celtics... in a fierce battle on the hardwood this Wednesday. The 2025-26 NBA season has just begun, and tensions be runnin' high... as the Sixers aim to improve their 24-58 record from last season.
The Celtics, who had a stellar 61-21 standing last regular season... be lookin' to continue their dominance at home. The atmosphere in the Boston Celtics arena be electric... with fans ready to cheer on their team to victory.
As the away team, the Philadelphia 76ers will have a tough challenge... against the talented Celtics squad. Be sure to review the best point spread, total, and moneyline bets... from our partner sportsbooks below to make yer wagers.
And don't forget to look at the prop bets for this game... to add even more excitement to the matchup. So grab yer rum and get ready... for some NBA action like ye've never seen before! Arrr!
Best Sixers at Celtics Odds
| Underdog Philadelphia 76ers | Favorite Boston Celtics |
|---|---|
| Over | Under |
|---|---|
| Underdog Philadelphia 76ers | Favorite Boston Celtics |
|---|---|
Matchup Odds FAQs
The Boston Celtics are -2.5 -115 point spread favorites at BetMGM, while the Philadelphia 76ers are +2.5 -105 point spread underdogs at BetMGM.
The best over line is 225.5 -115 points at BetMGM, which means you risk $115 to win $100 betting the over. The best under line is 225.5 -105 points at BetMGM, and that means you risk $105 to win $100 betting the under.
The Boston Celtics are the -145 moneyline favorite at BetMGM and the Philadelphia 76ers are the +118 moneyline underdog at BetMGM.
NBA Odds Example
|
Game |
 BetMGMBet |
|---|---|
Sixers
Celtics
10/22/25 7:30pm EDT | +2.5 -105-2.5 -115 |
Underdog Philadelphia 76ers - Philadelphia 76ers bettors risk $100 to win $95.24 at -105 odds.
A +2.5 Philadelphia 76ers underdog bet wins if they lose by 2 or fewer, tie, or win outright. Your bet loses if they lose by 3 or more.
Favorite Boston Celtics - Boston Celtics bettors risk $100 to win $86.96 at -115 odds.
A -2.5 Boston Celtics favorite bet wins if they win by 3 or more. Your bet loses if they win by 2 or fewer, tie, or lose outright.
Philadelphia 76ers at Boston Celtics Prop Bets
| BetMGM Bet |
|
|---|---|
Sixers
Celtics
10/22/25 7:30pm EDT | Pending BetMGM |
Team Standings
| Team | W | L | Pct | GB | Home | Away | Div | Conf | PPG | Op. PPG | Diff | Strk | L10 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Boston Celtics | 0 | 0 | 0.000 | 0.0 | 0-0 | 0-0 | 0-0 | 0-0 | 0.0 | 0.0 | 0.0 | - | - |
| Philadelphia 76ers | 0 | 0 | 0.000 | 0.0 | 0-0 | 0-0 | 0-0 | 0-0 | 0.0 | 0.0 | 0.0 | - | - |
Philadelphia 76ers & Boston Celtics Futures Odds
Latest NBA Championship odds, if available, for each team. Review odds for other teams and learn how to bet on the NBA Championship. See past Championship results and learn how to bet NBA Finals teasers, props and parlays.
Philadelphia 76ers Championship Odds|
Team | BetMGM |
|---|---|
| Sixers | +4000 Bet |
|
Team | BetMGM |
|---|---|
| Celtics | +6000 Bet |
Philadelphia 76ers & Boston Celtics Team Pages
Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the Philadelphia 76ers vs Boston Celtics NBA Game
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Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Wednesday, October 22nd, 2025 at 7:30 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
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Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
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Tap to the sportsbook's NBA page, look for the Philadelphia 76ers vs Boston Celtics Game.
Navigate to the sportsbook's NBA page. Next, look for live or upcoming matchups. Select the Philadelphia 76ers vs Boston Celtics Game.
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Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.
Other October 22, 2025 NBA Games
- Brooklyn Nets vs Charlotte Hornets - 10/22/25 7:00pm EDT
- Cleveland Cavaliers vs New York Knicks - 10/22/25 7:00pm EDT
- Miami Heat vs Orlando Magic - 10/22/25 7:00pm EDT
- Toronto Raptors vs Atlanta Hawks - 10/22/25 7:30pm EDT
- Washington Wizards vs Milwaukee Bucks - 10/22/25 8:00pm EDT
- New Orleans Pelicans vs Memphis Grizzlies - 10/22/25 8:00pm EDT
- Detroit Pistons vs Chicago Bulls - 10/22/25 8:00pm EDT
- Los Angeles Clippers vs Utah Jazz - 10/22/25 9:00pm EDT
- San Antonio Spurs vs Dallas Mavericks - 10/22/25 9:30pm EDT
- Sacramento Kings vs Phoenix Suns - 10/22/25 10:00pm EDT
- Minnesota Timberwolves vs Portland Trail Blazers - 10/22/25 10:00pm EDT