Buffalo vs DePaul Basketball Odds

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The Bulls will play the Blue Demons on Tuesday, November 11th, 2025. Your timezone's tip off time is 8:00 pm EST. Check local listings or your nearest streaming app for coverage.

Review our College Basketball Betting guide to learn how to bet this game.


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Table of Contents

Key Matchup Stats

The 2025-26 college basketball season has begun, with Buffalo and DePaul scheduled to matchup on Tuesday, November 11th, 2025. Let's review each team's key performance stats from the 2024-25 season to see what's in store for this early season matchup.

  • SportsBetting3.com Power Rankings - Buffalo had a 94.33 conference power ranking in the 2024-25 season. The conference power ranking for DePaul in the 2024-25 season was 94.67.
  • Away Buffalo - When the 2024-25 regular season ended, Buffalo had a 3-13 record as an away team, ranking them 6th in the MAC Conference for away team wins.
  • Home DePaul - As for DePaul, they finished the 2024-25 regular season with a 11-8 record as a home team. They ranked 4th in the Big East Conference for home team wins for the 2024-25 season.
  • Conference Win Percentage - Buffalo ended up ranking 8th (0.222) in the MAC Conference, with DePaul standing 8th (0.200) for their conference win percentage in the 2024 Big East Conference.
  • Overall Win Percentage - Buffalo finished the regular season with a 0.290 overall win percentage. Meanwhile, DePaul recorded a 0.412 overall win percentage.
  • Team Records - Buffalo had a 9-22 regular season overall record, with DePaul tallying a 14-20 regular season standing last year.

Moneyline Mage

Spelling out the winners with humor since the middle ages.

Moneyline Mage
Moneyline Mage

Hocus pocus, Buffalo faces DePaul in a magical clash on Tuesday night.

Buffalo had a rough 9-22 season, while DePaul ended at 14-20 last year. College conference records are key for tournament seeds. Buffalo was 4-14 in MAC, while DePaul had a 4-16 record in Big East.

Bet on this game with any of SportsBetting3.com's partner sportsbooks, review the odds before tipoff, and check out the team prop bets below.

Best Bulls at Blue Demons Odds


Best Point Spread Betting Odds
Underdog

Buffalo		Favorite

DePaul
+19.5 -115 BetMGM
Bet
-19.5 -105 BetMGM
Bet
DePaul has a -19.5 -105 point spread at BetMGM OH. They are the point spread favorite in this matchup. Buffalo has a +19.5 -115 point spread at BetMGM OH. Buffalo is the point spread underdog. Review how to bet on a point spread with our text and video tutorials.

Best Total Betting Odds
OverUnder
153.5 o -110 BetMGM
Bet
153.5 u -110 BetMGM
Bet
BetMGM has the best over line of 153.5 points. Risk $110 to win $100. BetMGM has the best under line of 153.5 points. Risk $110 to win $100. Our tutorial explains more about total bets.

Best Moneyline Betting Odds
TBDTBD
Moneyline odds are updating, please check back soon.

Matchup Odds FAQs

What is the point spread for the Buffalo vs DePaul College Basketball game on Tuesday, November 11th, 2025?

DePaul is a -19.5 -105 point spread favorite at BetMGM, while Buffalo is a +19.5 -115 point spread underdog at BetMGM.

What is the over-under total line for the Buffalo vs DePaul College Basketball game on Tuesday, November 11th, 2025?

The best over line is 153.5 -110 points at BetMGM, which means you risk $110 to win $100 betting the over. The best under line is 153.5 -110 points at BetMGM, and that means you risk $110 to win $100 betting the under.

College Basketball Odds Example

College Basketball Odds and Outcomes Explained

Game		 BetMGM Sports Betting BetMGM
Bet
Buffalo
DePaul
11/11/25 8:00pm EST
+19.5 -115-19.5 -105
Bet $100 at BetMGM Ohio
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Gambling Problem? Call 1-800-589-9966

Underdog Buffalo - Buffalo bettors risk $100 to win $86.96 at -115 odds.

A +19.5 Buffalo underdog bet wins if they lose by 19 or fewer, tie, or win outright. Your bet loses if they lose by 20 or more.

Favorite DePaul - DePaul bettors risk $100 to win $95.24 at -105 odds.

A -19.5 DePaul favorite bet wins if they win by 20 or more. Your bet loses if they win by 19 or fewer, tie, or lose outright.

Buffalo at DePaul Prop Bets

Important Note: Some states expressly forbid individual college athlete prop bets. The following wagers may not be available depending on your particular state laws.

College Basketball Prop Bets
+ Displays more odds
BetMGM Sports Betting BetMGM
Bet
Buffalo
DePaul
First to 5 Points
11/11/25 8:00pm EST
+150-210Bet
Buffalo
DePaul
First to 10 Points
11/11/25 8:00pm EST
+200-295Bet
Buffalo
DePaul
First to 15 Points
11/11/25 8:00pm EST
+250-375Bet
Buffalo
DePaul
Game to Overtime
11/11/25 8:00pm EST
Yes +2500No -10000Bet

Team Standings

2025-2026 College Basketball Regular Season Standings - Buffalo, DePaul
Team W-L Win% Home Away Conf CGB Conf% Strk
Big East
DePaul3-20.6003-20-00-0-0.000W1
MAC
Buffalo5-01.0004-01-00-0-0.000W5

Buffalo & DePaul Futures Odds

Latest College Basketball Championship odds, if available, for each team. Review March Madness odds for other teams and learn how to bet on the college basketball tournament. Also be sure to read Ron Halfback's Final Four write-up.

Buffalo Championship Odds

No NCAA Men's Basketball Tournament TM Buffalo YR: futures available

DePaul Championship Odds
2025-26 DePaul NCAA Men's Basketball Tournament Odds

Team		BetMGM Sports Betting BetMGM
DePaul		+100000
Bet

Buffalo & DePaul Team Pages

Review each team's futures odds, betting bonuses, current standings and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Buffalo vs DePaul College Basketball Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Tuesday, November 11th, 2025 at 8:00 pm EST, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's College Basketball page, look for the Buffalo vs DePaul Game.

    Navigate to the sportsbook's College Basketball page. Next, look for live or upcoming matchups. Select the Buffalo vs DePaul Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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