The Blue Devils will play the Cardinals on Tuesday, January 6th, 2026. Your timezone's tip off time is 7:00 pm EST. Check local listings or your nearest streaming app for coverage.
Review our College Basketball Betting guide to learn how to bet this game.
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Table of Contents
- Matchup Stats
- Moneyline Mage
- Best Odds
- Interactive Odds Example
- Prop Bets
- Team Standings
- Futures Odds
- Team Pages
- Other Games Today
Key Matchup Stats
Looking into the second half of the 2025-26 college basketball season, Duke and Louisville are set to hit the hardwood on Tuesday, January 6th, 2026. Luckily, we have some clear performance trends emerging now that each team has more than a dozen games under their belts. Use the following data to help analyze this matchup and to place an intelligent wager on its ultimate outcome.
- SportsBetting3.com Power Rankings - With the 2025-26 season in full stride, Duke currently has a 99.00 conference power ranking, while the SportsBetting3.com conference power ranking for Louisville is 96.33.
- Away Duke - Duke starts this game with a 3-0 record as an away team, ranking them 1st in the ACC Conference for away team wins.
- Home Louisville - Louisville meets Duke boasting a 8-0 record as a home team. They currently rank 4th in the ACC Conference for home team wins.
- Conference Win Percentage - Duke currently ranks 1st (1.000) in the ACC Conference, with Louisville now standing 2nd (0.500) for their conference win percentage in the 2025 ACC Conference for the 2025-26 college basketball season.
- Overall Win Percentage - Duke has a 0.929 overall win percentage, with Louisville matching up with a 0.786 overall win percentage.
- Team Records - Duke currently possesses 13-1 regular season overall record. Meanwhile, Louisville has tallied a 11-3 standing as the 2025-26 college basketball season continues to unfold.
Moneyline Mage
Spelling out the winners with humor since the middle ages.

Beware! Duke 13-1, Louisville 11-3 clash in battle of titans on Tuesday!
Conference records crucial for tournament seeds. Duke 2-0, Louisville 1-1 in ACC.
Duke on 2-game win streak, Louisville coming off loss. Watch out wizards! Review the tables below to find the best point spread, total, and moneylines for this game. You can bet on college basketball legally at BetRivers and BetMGM. We've also listed each team's futures odds and current standings below.
Best Blue Devils at Cardinals Odds
| Underdog Louisville | Favorite Duke |
|---|---|
| Over | Under |
|---|---|
| Underdog Louisville | Favorite Duke |
|---|---|
Matchup Odds FAQs
Duke is a -1.5 +100 point spread favorite at BetMGM, while Louisville is a +1.5 -120 point spread underdog at BetMGM.
The best over line is 161.5 -110 points at BetMGM, which means you risk $110 to win $100 betting the over. The best under line is 161.5 -110 points at BetMGM, and that means you risk $110 to win $100 betting the under.
Duke is a -110 moneyline favorite at BetMGM and Louisville is a -110 moneyline underdog at BetMGM.
College Basketball Odds Example
|
Game |
Bet |
|---|---|
Duke
Louisville
1/06/26 7:00pm EST | -1.5 +100+1.5 -120 |
Underdog Louisville - Louisville bettors risk $100 to win $83.33 at -120 odds.
A +1.5 Louisville underdog bet wins if they lose by 1, tie, or win outright. Your bet loses if they lose by 2 or more.
Favorite Duke - Duke bettors risk $100 to win $100 at +100 odds.
A -1.5 Duke favorite bet wins if they win by 2 or more. Your bet loses if they win by 1, tie, or lose outright.
Duke at Louisville Prop Bets
Important Note: Some states expressly forbid individual college athlete prop bets. The following wagers may not be available depending on your particular state laws.
Bet |
|
|---|---|
Duke
Louisville
First to 5 Points
1/06/26 7:00pm EST | -115-118Bet |
Duke
Louisville
First to 10 Points
1/06/26 7:00pm EST | -115-120Bet |
Duke
Louisville
First to 15 Points
1/06/26 7:00pm EST | -115-120Bet |
Duke
Louisville
Game to Overtime
1/06/26 7:00pm EST | Yes +800No -3000Bet |
Team Standings
| Team | W-L | Win% | Home | Away | Conf | CGB | Conf% | Strk |
|---|---|---|---|---|---|---|---|---|
| #4 Duke | 20-1 | 0.952 | 10-0 | 7-0 | 9-0 | - | 1.000 | W9 |
| #20 Louisville | 15-6 | 0.714 | 11-2 | 2-4 | 5-4 | +4 | 0.556 | W1 |
Duke & Louisville Futures Odds
Latest College Basketball Championship odds, if available, for each team. Review March Madness odds for other teams and learn how to bet on the college basketball tournament. Also be sure to read Ron Halfback's Final Four write-up.
Duke Championship Odds|
Team |
|---|
| OH,US ncaabb Evnum: 1 Odds Pending |
|
Team |
|---|
| OH,US ncaabb Evnum: 1 Odds Pending |
Duke & Louisville Team Pages
Review each team's futures odds, betting bonuses, current standings and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the Duke vs Louisville College Basketball Game
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Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Tuesday, January 6th, 2026 at 7:00 pm EST, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
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Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
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Tap to the sportsbook's College Basketball page, look for the Duke vs Louisville Game.
Navigate to the sportsbook's College Basketball page. Next, look for live or upcoming matchups. Select the Duke vs Louisville Game.
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Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.
Other January 6, 2026 NCAABB Games
- UMass vs Ohio
- Central Michigan vs Akron
- Cincinnati vs West Virginia
- Western Michigan vs Miami (OH)
- South Carolina vs LSU
- Bowling Green vs Kent State
- Syracuse vs Georgia Tech
- St. John's vs Butler
- Eastern Michigan vs Ball State
- Georgia vs Florida
- Michigan vs Penn State
- George Washington vs Dayton
- Georgetown vs DePaul
- Iowa vs Minnesota
- Toledo vs Northern Illinois
- UCF vs Oklahoma State
- Lindenwood vs SIU Edwardsville
- TCU vs Kansas
- Texas Tech vs Houston
- UCLA vs Wisconsin
- New Mexico vs Colorado State
- NC State vs Boston College
- Utah State vs Air Force
- Texas vs Tennessee
- Texas A&M vs Auburn
- Fresno State vs San Jose State
- UNLV vs Wyoming
- San Diego State vs Nevada