Loyola Chicago vs San Francisco Basketball Odds

The Ramblers will play the Dons on Wednesday, December 17th, 2025. Your timezone's tip off time is 10:00 pm EST. Check local listings or your nearest streaming app for coverage.

Review our College Basketball Betting guide to learn how to bet this game.


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Table of Contents

Key Matchup Stats

The Loyola Chicago and San Francisco basketball teams will play on Wednesday, December 17th, 2025 as the 2025-26 college basketball season continues to roll along. Now that both teams have a few games under their belts, let’s size up this matchup by looking at some performance metrics and key stats.

  • SportsBetting3.com Power Rankings - Loyola Chicago currently has a 95.67 conference power ranking so far in the 2025-26 season. The SportsBetting3.com conference power ranking for San Francisco is 97.00.
  • Away Loyola Chicago - Loyola Chicago heads into this game with a 0-1 record as an away team, ranking them 3rd in the A-10 Conference for away team wins.
  • Home San Francisco - San Francisco will host Loyola Chicago sporting a 4-1 record as a home team. They currently rank 4th in the WCC Conference for home team wins for the 2025-26 season.
  • Conference Win Percentage - Loyola Chicago currently ranks 1st (0.000) in the A-10 Conference, with San Francisco now standing 1st (0.000) for their conference win percentage in the 2025 WCC Conference for the 2025-26 college basketball season.
  • Overall Win Percentage - Loyola Chicago has a 0.273 overall win percentage. Their opponent, San Francisco, has a 0.545 overall win percentage.
  • Team Records - Loyola Chicago has a 3-8 regular season overall record. San Francisco has notched a 6-5 standing so far in the 2025-26 college basketball season.

Moneyline Mage

Spelling out the winners with humor since the middle ages.

Moneyline Mage
Moneyline Mage

Hocus pocus! Loyola Chicago faces San Francisco in a magical basketball battle on Wednesday.

Loyola Chicago, with a 3-8 record, takes on San Francisco, who stands at 6-5. Bewitching!

Our point spread, total, and moneyline tables show the best lines and odds for this matchup. Place a bet at BetMGM or BetRivers for a chance at wizardly winnings. The importance of conference records looms large as teams jockey for tournament seeds. Loyola Chicago and San Francisco both seek a conference win to spark their season. Review each team’s futures odds and current standings below before the enchanted tip-off.

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Best Point Spread Betting Odds
Underdog

Loyola Chicago
Favorite

San Francisco
San Francisco has a -12.5 -112 point spread at BetRivers PA. They are the point spread favorite in this matchup. Loyola Chicago has a +12.5 -110 point spread at BetRivers PA. Loyola Chicago is the point spread underdog. Review how to bet on a point spread with our text and video tutorials.

Best Total Betting Odds
OverUnder
BetRivers has the best over line of 143.5 points. Risk $107 to win $100. BetRivers has the best under line of 143.5 points. Risk $117 to win $100. Our tutorial explains more about total bets.

Best Moneyline Betting Odds
Underdog

Loyola Chicago
Favorite

San Francisco
San Francisco is the -910 moneyline favorite. Risk $910 to win $100 on San Francisco at BetRivers. Loyola Chicago is the +550 underdog at BetRivers. Risk $100 to win $550 on Loyola Chicago. Learn more about how to bet on money lines.

Matchup Odds FAQs

What is the point spread for the Loyola Chicago vs San Francisco College Basketball game on Wednesday, December 17th, 2025?

San Francisco is a -12.5 -112 point spread favorite at BetRivers, while Loyola Chicago is a +12.5 -110 point spread underdog at BetRivers.

What is the over-under total line for the Loyola Chicago vs San Francisco College Basketball game on Wednesday, December 17th, 2025?

The best over line is 143.5 -107 points at BetRivers, which means you risk $107 to win $100 betting the over. The best under line is 143.5 -117 points at BetRivers, and that means you risk $117 to win $100 betting the under.

What is the moneyline for the Loyola Chicago vs San Francisco College Basketball game on Wednesday, December 17th, 2025?

San Francisco is a -910 moneyline favorite at BetRivers and Loyola Chicago is a +550 moneyline underdog at BetRivers.

College Basketball Odds Example

College Basketball Odds and Outcomes Explained

Game
BetRivers Sports Betting BetRivers
Bet
Loyola Chicago
San Francisco
12/17/25 10:00pm EST
+12.5 -110-12.5 -112
Bet $100 at BetRivers Pennsylvania
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Underdog Loyola Chicago - Loyola Chicago bettors risk $100 to win $90.91 at -110 odds.

A +12.5 Loyola Chicago underdog bet wins if they lose by 12 or fewer, tie, or win outright. Your bet loses if they lose by 13 or more.

Favorite San Francisco - San Francisco bettors risk $100 to win $89.29 at -112 odds.

A -12.5 San Francisco favorite bet wins if they win by 13 or more. Your bet loses if they win by 12 or fewer, tie, or lose outright.

Loyola Chicago at San Francisco Prop Bets

Important Note: Some states expressly forbid individual college athlete prop bets. The following wagers may not be available depending on your particular state laws.

College Basketball Prop Bets
+ Displays more odds
BetMGM Sports Betting BetMGM
Bet
Loyola Chicago
San Francisco
12/17/25 10:00pm EST
Pending BetMGM

Team Standings

2025-2026 College Basketball Regular Season Standings - Loyola Chicago, San Francisco
Team W-L Win% Home Away Conf CGB Conf% Strk
A-10
Loyola Chicago9-240.2736-101-104-14+110.222L1
WCC
San Francisco17-160.51510-64-78-10+80.444L1

Loyola Chicago & San Francisco Futures Odds

Latest College Basketball Championship odds, if available, for each team. Review March Madness odds for other teams and learn how to bet on the college basketball tournament. Also be sure to read Ron Halfback's Final Four write-up.

Loyola Chicago Championship Odds

No NCAA Men's Basketball Tournament TM Loyola Chicago YR: futures available

San Francisco Championship Odds

No NCAA Men's Basketball Tournament TM San Francisco YR: futures available

Loyola Chicago & San Francisco Team Pages

Review each team's futures odds, betting bonuses, current standings and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Loyola Chicago vs San Francisco College Basketball Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Wednesday, December 17th, 2025 at 10:00 pm EST, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's College Basketball page, look for the Loyola Chicago vs San Francisco Game.

    Navigate to the sportsbook's College Basketball page. Next, look for live or upcoming matchups. Select the Loyola Chicago vs San Francisco Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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