Clemson Tigers vs Louisville Cardinals Football Lines

Odds Preview 1996

The Tigers will play the Cardinals on Saturday, November 6th, 2021. The matchup takes place at Cardinal Stadium. Watch this exciting week 10 matchup at 7:30 pm on ACCN.

Best Underdog and Favorite Spread Bets
Underdog

Louisville
Favorite

Clemson
+3.5 -105 Sb3gen1 -3.5 -110 Sb3gen2
+3.5 -110 Sb3gen2 -3.5 -110 Sb3gen3
+3.5 -110 Sb3gen3 -3.5 -115 Sb3gen1
SportsBetting3.com has analyzed the latest lines. Review our "Best Spread Bets" table above to smash the books this Saturday. Sb3gen2 has the best favorite Clemson spread at -3.5 points. Sb3gen1 has the best underdog Louisville spread at +3.5 points.

Review our point spread betting tutorial and video for more information.
Best Over and Under Total Lines
OverUnder
46o -110 Sb3gen2 46.5u -110 Sb3gen1
46.5o -110 Sb3gen1 46.5u -110 Sb3gen3
46.5o -110 Sb3gen3 46u -110 Sb3gen2
The over under line estimates the combined total of each team's final score. Sb3gen2 has the best over line of 46 points laying $110 to win $100. Sb3gen1 has the best under line of 46.5 u -110.
Best Money Line Bets
Underdog

Louisville
Favorite

Clemson
+157 Sb3gen1 -177 Sb3gen1
+155 Sb3gen2 -180 Sb3gen2
+150 Sb3gen3 -180 Sb3gen3
Here are money lines for the outright winner. Favorite Clemson has a minus value. Lay $177 at Sb3gen1 to win $100. Underdog Louisville has a positive value. Risk $100 at Sb3gen1 to win $157.

College Football Championship Odds

Latest NCAA Championship odds, if available, for each team. Review odds for other teams and learn the best College Football bets here.

Clemson Championship Odds
OutcomeSB3Gen SB3Gen

Cached 2021-12-05 18:38:16
Louisville Championship Odds
OutcomeSB3Gen SB3Gen

Cached 2021-12-05 18:38:16

2021 Clemson Games & Results

WeekMatchupDate & Time
1 Georgia vs
Clemson
UGA 10, CLEM 3
09/04/2021
2 South Carolina State vs
Clemson
CLEM 49, SCST 3
09/11/2021
3 Georgia Tech vs
Clemson
CLEM 14, GT 8
09/18/2021
4 Clemson vs
NC State
NCST 27, CLEM 21 (2OT)
09/25/2021
5 Boston College vs
Clemson
CLEM 19, BC 13
10/02/2021
7 Clemson vs
Syracuse
CLEM 17, SYR 14
10/15/2021
8 Clemson vs
Pittsburgh
PITT 27, CLEM 17
10/23/2021
9 Florida State vs
Clemson
CLEM 30, FSU 20
10/30/2021
10 Clemson vs
Louisville
CLEM 30, LOU 24
11/06/2021
11 UConn vs
Clemson
11/13/2021
12:00PM
12 Wake Forest vs
Clemson
CLEM 48, WAKE 27
11/20/2021
13 Clemson vs
South Carolina
CLEM 30, SC 0
11/27/2021

2021 Louisville Games & Results

WeekMatchupDate & Time
1 Louisville vs
Ole Miss
MISS 43, LOU 24
09/06/2021
2 Eastern Kentucky vs
Louisville
LOU 30, EKU 3
09/11/2021
3 UCF vs
Louisville
LOU 42, UCF 35
09/17/2021
4 Louisville vs
Florida State
LOU 31, FSU 23
09/25/2021
5 Louisville vs
Wake Forest
WAKE 37, LOU 34
10/02/2021
6 Virginia vs
Louisville
UVA 34, LOU 33
10/09/2021
8 Boston College vs
Louisville
LOU 28, BC 14
10/23/2021
9 Louisville vs
NC State
NCST 28, LOU 13
10/30/2021
10 Clemson vs
Louisville
CLEM 30, LOU 24
11/06/2021
11 Syracuse vs
Louisville
11/13/2021
12:00PM
12 Louisville vs
Duke
LOU 62, DUKE 22
11/18/2021
13 Kentucky vs
Louisville
UK 52, LOU 21
11/27/2021

Other 2021 Week 10 Matchups

MatchupDate & Time
Ball State vs
Akron
BALL 31, AKR 25
11/02/2021
Miami (OH) vs
Ohio
OHIO 35, M-OH 33
11/02/2021
Eastern Michigan vs
Toledo
EMU 52, TOL 49
11/02/2021
Central Michigan vs
Western Michigan
CMU 42, WMU 30
11/03/2021
Northern Illinois vs
Kent State
KENT 52, NIU 47
11/03/2021
Georgia State vs
Louisiana
UL 21, GAST 17
11/04/2021
Virginia Tech vs
Boston College
BC 17, VT 3
11/05/2021
Utah vs
Stanford
UTAH 52, STAN 7
11/05/2021
Army vs
Air Force
ARMY 21, AFA 14 (OT)
11/06/2021
Missouri vs
Georgia
UGA 43, MIZ 6
11/06/2021
Ohio State vs
Nebraska
OSU 26, NEB 17
11/06/2021
Wake Forest vs
North Carolina
UNC 58, WAKE 55
11/06/2021
Liberty vs
Ole Miss
MISS 27, LIB 14
11/06/2021
Illinois vs
Minnesota
ILL 14, MINN 6
11/06/2021
Pittsburgh vs
Duke
PITT 54, DUKE 29
11/06/2021
Louisiana Tech vs
UAB
UAB 52, LT 38
11/06/2021
Kansas State vs
Kansas
KSU 35, KU 10
11/06/2021
SMU vs
Memphis
MEM 28, SMU 25
11/06/2021
Georgia Tech vs
Miami (FL)
MIA 33, GT 30
11/06/2021
Appalachian State vs
Arkansas State
APP 48, ARST 14
11/06/2021
North Texas vs
Southern Miss
UNT 38, USM 14
11/06/2021
Temple vs
East Carolina
ECU 45, TEM 3
11/06/2021
Louisiana-Monroe vs
Texas State
TXST 27, ULM 19
11/06/2021
California vs
Arizona
ARIZ 10, CAL 3
11/06/2021
Tulsa vs
Cincinnati
CIN 28, TLSA 20
11/06/2021
Navy vs
Notre Dame
ND 34, NAVY 6
11/06/2021
Oklahoma State vs
West Virginia
OKST 24, WVU 3
11/06/2021
Baylor vs
TCU
TCU 30, BAY 28
11/06/2021
Auburn vs
Texas A&M
TA&M 20, AUB 3
11/06/2021
Idaho State vs
BYU
BYU 59, IDST 14
11/06/2021
Wisconsin vs
Rutgers
WISC 52, RUTG 3
11/06/2021
Rice vs
Charlotte
CLT 31, RICE 24 (OT)
11/06/2021
Middle Tennessee vs
Western Kentucky
WKU 48, MTSU 21
11/06/2021
Penn State vs
Maryland
PSU 31, MD 14
11/06/2021
Rhode Island vs
UMass
URI 35, MASS 22
11/06/2021