The Buffaloes will play the Cougars on Friday, September 12th, 2025. The matchup takes place at TDECU Stadium. Watch this exciting Week 3 matchup at 7:30 pm EDT. Check local listings for coverage on ESPN.
Learn more about College Football betting with our handy tutorial and guide. We explain spread, total and money line bets.
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Table of Contents
- Matchup Stats
- Paddy O'Parlay
- Best Odds
- Interactive Odds Example
- Prop Bets
- Recent Meetings
- Team Standings
- Futures Odds
- Team Pages
- Team Schedules & Results
- Other Games Today
Key Matchup Stats
The 2025 college football season continues with Colorado matching up against Houston at TDECU Stadium. Let's review how each team is doing so far to better understand how this game will play out.
- SportsBetting3.com Power Rankings - Colorado has a 95.00 conference power ranking for the 2025 season so far. The 2025 conference power ranking for Houston is 97.33.
- Away Colorado - Colorado currently has a 0-0 record as an away team for the 2025 regular season, ranking them 2nd in the Big 12 Conference for away team wins. Not much can be concluded from this stat just yet, so stay tuned.
- Home Houston - So far, Houston has a 1-0 record as a home team. They currently rank 2nd in the Big 12 Conference for home team wins in 2025. Keep tabs on this figure, as it will change in the coming weeks.
- Points Scored - Colorado ranks 13th (51) in the Big 12 Conference, with Houston currently ranking 10th (62) for points scored in the 2025 Big 12 Conference.
- Points Against - Colorado stands 7th (34) in the Big 12 Conference for points scored by opponents in 2025. Houston sits at 13th (9) in the 2025 Big 12 Conference for points against in the 2025 season.
- Team Records - Colorado has a 1-1 regular season overall record, with Houston currently possessing a 2-0 regular season standing for the 2025 NCAAF season.
Paddy O'Parlay
The "Sports Network" talking heads have nothing on my Irish arse!
Get ready for a wild showdown at TDECU Stadium as Colorado takes on Houston this Friday!
Houston is looking to defend their home turf in this crucial early season matchup.
With Colorado at 1-1 and Houston at 2-0, anything can happen - review this game's prop bets at SportsBetting3.com and compare the odds below!
Best Buffaloes at Cougars Odds
| Underdog Colorado | Favorite Houston |
|---|---|
| Over | Under |
|---|---|
| Underdog Colorado | Favorite Houston |
|---|---|
Matchup Odds FAQs
Houston is a -4.5 -110 point spread favorite at BetMGM, while Colorado is a +4.5 -110 point spread underdog at BetMGM.
The best over line is 44.5 -115 points at BetMGM, which means you risk $115 to win $100 betting the over. The best under line is 44.5 -105 points at BetMGM, and that means you risk $105 to win $100 betting the under.
Houston is a -190 moneyline favorite at BetMGM and Colorado is a +155 moneyline underdog at BetMGM.
College Football Odds Example
|
Game |
 BetMGMBet |
|---|---|
Colorado
Houston
9/12/25 7:30pm EDT | +4.5 -110-4.5 -110 |
Underdog Colorado - Colorado bettors risk $100 to win $90.91 at -110 odds.
A +4.5 Colorado underdog bet wins if they lose by 4 or fewer, tie, or win outright. Your bet loses if they lose by 5 or more.
Favorite Houston - Houston bettors risk $100 to win $90.91 at -110 odds.
A -4.5 Houston favorite bet wins if they win by 5 or more. Your bet loses if they win by 4 or fewer, tie, or lose outright.
Colorado at Houston Prop Bets
Important Note: Some states expressly forbid individual college athlete prop bets. The following wagers may not be available depending on your particular state laws.
| BetMGM Bet |
|
|---|---|
Colorado
Houston
No Touchdown
To Score 1st Touchdown
9/12/25 7:30pm EDT | +115-165+10000Bet |
Colorado
Houston
Game to Overtime
9/12/25 7:30pm EDT | Yes +1050No -10000Bet |
Colorado
Houston
Both Teams Score 10+
9/12/25 7:30pm EDT | Yes -550No +375Bet |
Colorado
Houston
Both Teams Score 20+
9/12/25 7:30pm EDT | Yes +140No -180Bet |
| BetMGM | |
Colorado
Houston
Both Teams Score 30+
9/12/25 7:30pm EDT | Yes +825No -2000Bet |
Recent Meetings Since 2021
| Week | Game | Result | Margin |
|---|---|---|---|
| 2025 Week 3 | Colorado vs Houston Friday, September 12th, 2025 | HOU 36, COLO 20 TDECU Stadium | Houston by 16 |
Team Standings
| Team | Conf | Conf% | W | L | PF | PA | Home | Away | Strk |
|---|---|---|---|---|---|---|---|---|---|
| #22 Houston | 4-2 | 0.667 | 7 | 2 | 265 | 194 | 3-2 | 4-0 | L1 |
| Colorado | 1-5 | 0.167 | 3 | 6 | 198 | 271 | 3-3 | 0-3 | L2 |
Colorado & Houston Futures Odds
Latest NCAA Championship odds, if available, for each team. Review odds for other teams and learn the best College Football bets.
Colorado Championship OddsNo NCAA College Football Championship TM Colorado YR: futures available
Houston Championship Odds|
Team | BetMGM |
|---|---|
| Houston |
Colorado & Houston Team Pages
Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:
Team Schedules & Results
| Week | Matchup | Date & Result |
|---|---|---|
| Week 1 | Georgia Tech vs Colorado | GT 27, COLO 20 Friday, August 29th, 2025 |
| Week 2 | Delaware vs Colorado | COLO 31, DEL 7 Saturday, September 6th, 2025 |
| Week 3 | Colorado vs Houston | HOU 36, COLO 20 Friday, September 12th, 2025 |
| Week 4 | Wyoming vs Colorado | COLO 37, WYO 20 Saturday, September 20th, 2025 |
| Week 5 | BYU vs Colorado | BYU 24, COLO 21 Saturday, September 27th, 2025 |
| Week 6 | Colorado vs TCU | TCU 35, COLO 21 Saturday, October 4th, 2025 |
| Week 7 | Iowa State vs Colorado | COLO 24, ISU 17 Saturday, October 11th, 2025 |
| Week 9 | Colorado vs Utah | Saturday, October 25th, 2025 10:15 pm EDT |
| Week 10 | Arizona vs Colorado | Saturday, November 1st, 2025 12:00 am EDT |
| Week 11 | Colorado vs West Virginia | Saturday, November 8th, 2025 12:00 am EST |
| Week 13 | Arizona State vs Colorado | Saturday, November 22nd, 2025 12:00 am EST |
| Week 14 | Colorado vs Kansas State | Saturday, November 29th, 2025 12:00 am EST |
| Week | Matchup | Date & Result |
|---|---|---|
| Week 1 | Stephen F. Austin vs Houston | HOU 27, SFA 0 Thursday, August 28th, 2025 |
| Week 2 | Houston vs Rice | HOU 35, RICE 9 Saturday, September 6th, 2025 |
| Week 3 | Colorado vs Houston | HOU 36, COLO 20 Friday, September 12th, 2025 |
| Week 5 | Houston vs Oregon State | HOU 27, ORST 24 (OT) Friday, September 26th, 2025 |
| Week 6 | Texas Tech vs Houston | TTU 35, HOU 11 Saturday, October 4th, 2025 |
| Week 7 | Houston vs Oklahoma State | HOU 39, OKST 17 Saturday, October 11th, 2025 |
| Week 8 | Arizona vs Houston | HOU 31, ARIZ 28 Saturday, October 18th, 2025 |
| Week 9 | Houston vs Arizona State | Saturday, October 25th, 2025 8:00 pm EDT |
| Week 10 | West Virginia vs Houston | Saturday, November 1st, 2025 12:00 am EDT |
| Week 11 | Houston vs UCF | Friday, November 7th, 2025 12:00 am EST |
| Week 13 | TCU vs Houston | Saturday, November 22nd, 2025 12:00 am EST |
| Week 14 | Houston vs Baylor | Saturday, November 29th, 2025 12:00 am EST |
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the Colorado vs Houston College Football Game
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Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Friday, September 12th, 2025 at 7:30 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
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Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
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Tap to the sportsbook's College Football page, look for the Colorado vs Houston Game.
Navigate to the sportsbook's College Football page. Next, look for live or upcoming matchups. Select the Colorado vs Houston Game.
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Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.