Colorado vs Houston Football Odds

The Buffaloes will play the Cougars on Friday, September 12th, 2025. The matchup takes place at TDECU Stadium. Watch this exciting Week 3 matchup at 7:30 pm EDT. Check local listings for coverage on ESPN.

Learn more about College Football betting with our handy tutorial and guide. We explain spread, total and money line bets.


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Table of Contents

Key Matchup Stats

The 2025 college football season continues with Colorado matching up against Houston at TDECU Stadium. Let's review how each team is doing so far to better understand how this game will play out.

  • SportsBetting3.com Power Rankings - Colorado has a 95.00 conference power ranking for the 2025 season so far. The 2025 conference power ranking for Houston is 97.33.
  • Away Colorado - Colorado currently has a 0-0 record as an away team for the 2025 regular season, ranking them 2nd in the Big 12 Conference for away team wins. Not much can be concluded from this stat just yet, so stay tuned.
  • Home Houston - So far, Houston has a 1-0 record as a home team. They currently rank 2nd in the Big 12 Conference for home team wins in 2025. Keep tabs on this figure, as it will change in the coming weeks.
  • Points Scored - Colorado ranks 13th (51) in the Big 12 Conference, with Houston currently ranking 10th (62) for points scored in the 2025 Big 12 Conference.
  • Points Against - Colorado stands 7th (34) in the Big 12 Conference for points scored by opponents in 2025. Houston sits at 13th (9) in the 2025 Big 12 Conference for points against in the 2025 season.
  • Team Records - Colorado has a 1-1 regular season overall record, with Houston currently possessing a 2-0 regular season standing for the 2025 NCAAF season.

Paddy O'Parlay

The "Sports Network" talking heads have nothing on my Irish arse!

Paddy O'Parlay
Paddy O'Parlay

Get ready for a wild showdown at TDECU Stadium as Colorado takes on Houston this Friday!

Houston is looking to defend their home turf in this crucial early season matchup.

With Colorado at 1-1 and Houston at 2-0, anything can happen - review this game's prop bets at SportsBetting3.com and compare the odds below!

Best Buffaloes at Cougars Odds


Best Point Spread Betting Odds
Underdog

Colorado
Favorite

Houston
Houston has a -5.5 -105 point spread at BetMGM OH. They are the point spread favorite in this matchup. Colorado has a +5.5 -115 point spread at BetMGM OH. Colorado is the point spread underdog. Review how to bet on a point spread with our text and video tutorials.

Best Total Betting Odds
OverUnder
BetMGM has the best over line of 43.5 points. Risk $115 to win $100. BetMGM has the best under line of 43.5 points. Risk $105 to win $100. Our tutorial explains more about total bets.

Best Moneyline Betting Odds
Underdog

Colorado
Favorite

Houston
Houston is the -220 moneyline favorite. Risk $220 to win $100 on Houston at BetMGM. Colorado is the +180 underdog at BetMGM. Risk $100 to win $180 on Colorado. Learn more about how to bet on money lines.

Matchup Odds FAQs

What is the point spread for the Colorado vs Houston College Football game on Friday, September 12th, 2025?

Houston is a -5.5 -105 point spread favorite at BetMGM, while Colorado is a +5.5 -115 point spread underdog at BetMGM.

What is the over-under total line for the Colorado vs Houston College Football game on Friday, September 12th, 2025?

The best over line is 43.5 -115 points at BetMGM, which means you risk $115 to win $100 betting the over. The best under line is 43.5 -105 points at BetMGM, and that means you risk $105 to win $100 betting the under.

What is the moneyline for the Colorado vs Houston College Football game on Friday, September 12th, 2025?

Houston is a -220 moneyline favorite at BetMGM and Colorado is a +180 moneyline underdog at BetMGM.

College Football Odds Example

College Football Odds and Outcomes Explained

Game
BetMGM Sports Betting BetMGM
Bet
Colorado
Houston
9/12/25 7:30pm EDT
+5.5 -115-5.5 -105
Bet $100 at BetMGM Ohio
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Gambling Problem? Call 1-800-589-9966

Underdog Colorado - Colorado bettors risk $100 to win $86.96 at -115 odds.

A +5.5 Colorado underdog bet wins if they lose by 5 or fewer, tie, or win outright. Your bet loses if they lose by 6 or more.

Favorite Houston - Houston bettors risk $100 to win $95.24 at -105 odds.

A -5.5 Houston favorite bet wins if they win by 6 or more. Your bet loses if they win by 5 or fewer, tie, or lose outright.

Colorado at Houston Prop Bets

Important Note: Some states expressly forbid individual college athlete prop bets. The following wagers may not be available depending on your particular state laws.

College Football Prop Bets
+ Displays more odds
BetMGM Sports Betting BetMGM
Bet
Colorado
Houston
9/12/25 7:30pm EDT
Pending BetMGM

Recent Meetings Since 2021

Recent Meetings Since 2021
WeekGameResultMargin

Team Standings

2025-2026 College Football Regular Season Standings - Colorado, Houston
Team Conf Conf% W L PF PA Home Away Strk
Colorado0-00.0001151341-10-0W1
Houston0-00.000206291-01-0W2

Colorado & Houston Futures Odds

Latest NCAA Championship odds, if available, for each team. Review odds for other teams and learn the best College Football bets.

Colorado Championship Odds
2025-26 Colorado NCAA College Football Championship Odds

Team
BetMGM Sports Betting BetMGM
Colorado
+30000
Bet
Houston Championship Odds
2025-26 Houston NCAA College Football Championship Odds

Team
BetMGM Sports Betting BetMGM
Houston
+25000
Bet

Colorado & Houston Team Pages

Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Schedules & Results


2025-26 Colorado Games & Results
WeekMatchupDate & Result
Week 1Georgia Tech vs
Colorado
GT 27, COLO 20
Friday, August 29th, 2025
Week 2Delaware vs
Colorado
COLO 31, DEL 7
Saturday, September 6th, 2025
Week 3Colorado vs
Houston
Friday, September 12th, 2025
7:30 pm EDT
Week 4Wyoming vs
Colorado
Saturday, September 20th, 2025
12:00 am EDT
Week 5BYU vs
Colorado
Saturday, September 27th, 2025
10:15 pm EDT
Week 6Colorado vs
TCU
Saturday, October 4th, 2025
12:00 am EDT
Week 7Iowa State vs
Colorado
Saturday, October 11th, 2025
12:00 am EDT
Week 9Colorado vs
Utah
Saturday, October 25th, 2025
12:00 am EDT
Week 10Arizona vs
Colorado
Saturday, November 1st, 2025
12:00 am EDT
Week 11Colorado vs
West Virginia
Saturday, November 8th, 2025
12:00 am EST
Week 13Arizona State vs
Colorado
Saturday, November 22nd, 2025
12:00 am EST
Week 14Colorado vs
Kansas State
Saturday, November 29th, 2025
12:00 am EST


2025-26 Houston Games & Results
WeekMatchupDate & Result
Week 1Stephen F. Austin vs
Houston
HOU 27, SFA 0
Thursday, August 28th, 2025
Week 2Houston vs
Rice
HOU 35, RICE 9
Saturday, September 6th, 2025
Week 3Colorado vs
Houston
Friday, September 12th, 2025
7:30 pm EDT
Week 5Houston vs
Oregon State
Friday, September 26th, 2025
10:30 pm EDT
Week 6Texas Tech vs
Houston
Saturday, October 4th, 2025
12:00 am EDT
Week 7Houston vs
Oklahoma State
Saturday, October 11th, 2025
12:00 am EDT
Week 8Arizona vs
Houston
Saturday, October 18th, 2025
12:00 am EDT
Week 9Houston vs
Arizona State
Saturday, October 25th, 2025
12:00 am EDT
Week 10West Virginia vs
Houston
Saturday, November 1st, 2025
12:00 am EDT
Week 11Houston vs
UCF
Friday, November 7th, 2025
12:00 am EST
Week 13TCU vs
Houston
Saturday, November 22nd, 2025
12:00 am EST
Week 14Houston vs
Baylor
Saturday, November 29th, 2025
12:00 am EST

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Colorado vs Houston College Football Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Friday, September 12th, 2025 at 7:30 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's College Football page, look for the Colorado vs Houston Game.

    Navigate to the sportsbook's College Football page. Next, look for live or upcoming matchups. Select the Colorado vs Houston Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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