The Blue Devils will play the Cavaliers on Saturday, December 6th, 2025. The matchup takes place at Bank of America Stadium. Watch this exciting Week 15 matchup at 8:10 pm EST. Check local listings for coverage on ABC.
Learn more about College Football betting with our handy tutorial and guide. We explain spread, total and money line bets.
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Table of Contents
- Best Odds
- Interactive Odds Example
- Prop Bets
- Recent Meetings
- Team Standings
- Futures Odds
- Team Pages
- Team Schedules & Results
- Other Games Today
Best Blue Devils at Cavaliers Odds
| Underdog Duke | Favorite Virginia |
|---|---|
| Over | Under |
|---|---|
| Underdog Duke | Favorite Virginia |
|---|---|
Matchup Odds FAQs
Virginia is a -3.5 -105 point spread favorite at BetMGM, while Duke is a +3.5 -115 point spread underdog at BetMGM.
The best over line is 57.5 -115 points at BetMGM, which means you risk $115 to win $100 betting the over. The best under line is 57.5 -105 points at BetMGM, and that means you risk $105 to win $100 betting the under.
Virginia is a -165 moneyline favorite at BetMGM and Duke is a +140 moneyline underdog at BetMGM.
College Football Odds Example
|
Game |
 BetMGMBet |
|---|---|
Duke
Virginia
12/06/25 8:10pm EST | +3.5 -115-3.5 -105 |
Underdog Duke - Duke bettors risk $100 to win $86.96 at -115 odds.
A +3.5 Duke underdog bet wins if they lose by 3 or fewer, tie, or win outright. Your bet loses if they lose by 4 or more.
Favorite Virginia - Virginia bettors risk $100 to win $95.24 at -105 odds.
A -3.5 Virginia favorite bet wins if they win by 4 or more. Your bet loses if they win by 3 or fewer, tie, or lose outright.
Duke at Virginia Prop Bets
Important Note: Some states expressly forbid individual college athlete prop bets. The following wagers may not be available depending on your particular state laws.
| BetMGM Bet |
|
|---|---|
Duke
Virginia
No Touchdown
To Score 1st Touchdown
12/06/25 8:10pm EST | +105-150+10000Bet |
Duke
Virginia
Game to Overtime
12/06/25 8:10pm EST | Yes +1050No -10000Bet |
Duke
Virginia
Both Teams Score 10+
12/06/25 8:10pm EST | Yes -2500No +950Bet |
Duke
Virginia
Both Teams Score 20+
12/06/25 8:10pm EST | Yes -220No +170Bet |
| BetMGM | |
Duke
Virginia
Both Teams Score 30+
12/06/25 8:10pm EST | Yes +275No -375Bet |
Recent Meetings Since 2021
| Week | Game | Result | Margin |
|---|---|---|---|
| 2025 Week 15 | Duke vs Virginia Saturday, December 6th, 2025 | DUKE 27, UVA 20 (OT) Bank of America Stadium | Duke by 7 |
| 2025 Week 12 | Virginia vs Duke Saturday, November 15th, 2025 | UVA 34, DUKE 17 Wallace Wade Stadium | Virginia by 17 |
| 2023 Week 12 | Duke vs Virginia Saturday, November 18th, 2023 | UVA 30, DUKE 27 Scott Stadium | Virginia by 3 |
| 2022 Week 5 | Virginia vs Duke Saturday, October 1st, 2022 | DUKE 38, UVA 17 Wallace Wade Stadium | Duke by 21 |
| 2021 Week 7 | Duke vs Virginia Saturday, October 16th, 2021 | UVA 48, DUKE 0 Scott Stadium | Virginia by 48 |
Team Standings
| Team | Conf | Conf% | W | L | PF | PA | Home | Away | Strk |
|---|---|---|---|---|---|---|---|---|---|
| #19 Virginia | 7-1 | 0.875 | 11 | 3 | 431 | 274 | 6-1 | 4-1 | W1 |
| Duke | 6-2 | 0.750 | 9 | 5 | 484 | 412 | 3-3 | 4-2 | W4 |
Duke & Virginia Futures Odds
Latest NCAA Championship odds, if available, for each team. Review odds for other teams and learn the best College Football bets.
Duke Championship OddsNo NCAA College Football Championship TM Duke YR: futures available
Virginia Championship OddsNo NCAA College Football Championship TM Virginia YR: futures available
Duke & Virginia Team Pages
Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:
Team Schedules & Results
| Week | Matchup | Date & Result |
|---|---|---|
| Week 1 | Elon vs Duke | DUKE 45, ELON 17 Thursday, August 28th, 2025 |
| Week 2 | Illinois vs Duke | ILL 45, DUKE 19 Saturday, September 6th, 2025 |
| Week 3 | Duke vs Tulane | TULN 34, DUKE 27 Saturday, September 13th, 2025 |
| Week 4 | NC State vs Duke | DUKE 45, NCSU 33 Saturday, September 20th, 2025 |
| Week 5 | Duke vs Syracuse | DUKE 38, SYR 3 Saturday, September 27th, 2025 |
| Week 6 | Duke vs California | DUKE 45, CAL 21 Saturday, October 4th, 2025 |
| Week 8 | Georgia Tech vs Duke | GT 27, DUKE 18 Saturday, October 18th, 2025 |
| Week 10 | Duke vs Clemson | DUKE 46, CLEM 45 Saturday, November 1st, 2025 |
| Week 11 | Duke vs UConn | CONN 37, DUKE 34 Saturday, November 8th, 2025 |
| Week 12 | Virginia vs Duke | UVA 34, DUKE 17 Saturday, November 15th, 2025 |
| Week 13 | Duke vs North Carolina | DUKE 32, UNC 25 Saturday, November 22nd, 2025 |
| Week 14 | Wake Forest vs Duke | DUKE 49, WAKE 32 Saturday, November 29th, 2025 |
| Week 15 | Duke vs Virginia | DUKE 27, UVA 20 (OT) Saturday, December 6th, 2025 |
| Bowls | Arizona State vs Duke Tony The Tiger Sun Bowl | DUKE 42, ASU 39 Wednesday, December 31st, 2025 |
| Week | Matchup | Date & Result |
|---|---|---|
| Week 1 | Coastal Carolina vs Virginia | UVA 48, CCU 7 Saturday, August 30th, 2025 |
| Week 2 | Virginia vs NC State | NCSU 35, UVA 31 Saturday, September 6th, 2025 |
| Week 3 | William & Mary vs Virginia | UVA 55, W&M 16 Saturday, September 13th, 2025 |
| Week 4 | Stanford vs Virginia | UVA 48, STAN 20 Saturday, September 20th, 2025 |
| Week 5 | Florida State vs Virginia | UVA 46, FSU 38 (2OT) Friday, September 26th, 2025 |
| Week 6 | Virginia vs Louisville | UVA 30, LOU 27 (OT) Saturday, October 4th, 2025 |
| Week 8 | Washington State vs Virginia | UVA 22, WSU 20 Saturday, October 18th, 2025 |
| Week 9 | Virginia vs North Carolina | UVA 17, UNC 16 (OT) Saturday, October 25th, 2025 |
| Week 10 | Virginia vs California | UVA 31, CAL 21 Saturday, November 1st, 2025 |
| Week 11 | Wake Forest vs Virginia | WAKE 16, UVA 9 Saturday, November 8th, 2025 |
| Week 12 | Virginia vs Duke | UVA 34, DUKE 17 Saturday, November 15th, 2025 |
| Week 14 | Virginia Tech vs Virginia | UVA 27, VT 7 Saturday, November 29th, 2025 |
| Week 15 | Duke vs Virginia | DUKE 27, UVA 20 (OT) Saturday, December 6th, 2025 |
| Bowls | Virginia vs Missouri Taxslayer Gator Bowl | UVA 13, MIZ 7 Saturday, December 27th, 2025 |
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the Duke vs Virginia College Football Game
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Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Saturday, December 6th, 2025 at 8:10 pm EST, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
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Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
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Tap to the sportsbook's College Football page, look for the Duke vs Virginia Game.
Navigate to the sportsbook's College Football page. Next, look for live or upcoming matchups. Select the Duke vs Virginia Game.
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Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.
Other December 6, 2025 NCAAFB Games
- BYU vs Texas Tech
- Villanova vs Lehigh
- South Dakota vs Mercer
- Miami (OH) vs Western Michigan
- Illinois State vs North Dakota State
- North Dakota vs Tarleton
- Prairie View A&M vs Jackson State
- Yale vs Montana State
- South Dakota State vs Montana
- Abilene Christian vs Stephen F. Austin
- Alabama vs Georgia
- Georgia vs Alabama
- Indiana vs Ohio State
- Rhode Island vs UC Davis