Eastern Kentucky vs Louisville Football Odds

The Colonels will play the Cardinals on Saturday, August 30th, 2025. The matchup takes place at L&N Federal Credit Union Stadium. Watch this exciting Week 1 matchup at 3:00 pm EDT. Check local listings for coverage on ACC Network.

Learn more about College Football betting with our handy tutorial and guide. We explain spread, total and money line bets.


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Table of Contents

Key Matchup Stats

The 2025 college football season has begun, with Eastern Kentucky and Louisville scheduled to matchup at L&N Federal Credit Union Stadium. First, let's review each team's stats from the 2024 season to get an idea of what we can expect on gameday.

  • SportsBetting3.com Power Rankings - Eastern Kentucky had a 97.00 conference power ranking in the 2024 season. The conference power ranking for Louisville in the 2024 season was 98.00.
  • Away Eastern Kentucky - At the end of the 2024 regular season, Eastern Kentucky had a 2-5 record as an away team, ranking them 4th in the UAC Conference for away team wins.
  • Home Louisville - Louisville finished the 2024 regular season with a 4-2 record as a home team. They ranked 3rd in the ACC Conference for home team wins in 2024.
  • Points Scored - Eastern Kentucky wound up 6th (291) in the UAC Conference, with Louisville ranked 4th (474) for points scored in the 2024 ACC Conference.
  • Points Against - Eastern Kentucky finished 8th (308) in the UAC Conference for points scored by opponents in 2024. Louisville wound up 13th (313) in the 2024 ACC Conference for points against.
  • Team Records - Eastern Kentucky had a 8-5 regular season overall record, with Louisville notching a 9-4 regular season standing last year.

Paddy O'Parlay

The "Sports Network" talking heads have nothing on my Irish arse!

Paddy O'Parlay
Paddy O'Parlay

Are you ready for some college football madness? Eastern Kentucky vs. Louisville, August 30th!

The battle begins at L&N Federal Credit Union Stadium, where the teams clash. Eastern Kentucky, with an 8-5 record, faces Louisville, standing at 9-4.

Expect a fierce showdown as these teams fight to kick off the season right. SportsBetting3.com has all the details - bet on this game and review the odds below. Let the games begin!

Best Colonels at Cardinals Odds


Best Point Spread Betting Odds
Underdog

Eastern Kentucky
Favorite

Louisville
Louisville has a -37.5 -110 point spread at BetMGM OH. They are the point spread favorite in this matchup. Eastern Kentucky has a +37.5 -110 point spread at BetMGM OH. Eastern Kentucky is the point spread underdog. Review how to bet on a point spread with our text and video tutorials.

Best Total Betting Odds
OverUnder
BetMGM has the best over line of 56.5 points. Risk $110 to win $100. BetMGM has the best under line of 56.5 points. Risk $110 to win $100. Our tutorial explains more about total bets.

Best Moneyline Betting Odds
TBDTBD
Moneyline odds are updating, please check back soon.

Matchup Odds FAQs

What is the point spread for the Eastern Kentucky vs Louisville College Football game on Saturday, August 30th, 2025?

Louisville is a -37.5 -110 point spread favorite at BetMGM, while Eastern Kentucky is a +37.5 -110 point spread underdog at BetMGM.

What is the over-under total line for the Eastern Kentucky vs Louisville College Football game on Saturday, August 30th, 2025?

The best over line is 56.5 -110 points at BetMGM, which means you risk $110 to win $100 betting the over. The best under line is 56.5 -110 points at BetMGM, and that means you risk $110 to win $100 betting the under.

College Football Odds Example

College Football Odds and Outcomes Explained

Game
BetMGM Sports Betting BetMGM
Bet
Eastern Kentucky
Louisville
8/30/25 3:00pm EDT
+37.5 -110-37.5 -110
Bet $100 at BetMGM Ohio
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Underdog Eastern Kentucky - Eastern Kentucky bettors risk $100 to win $90.91 at -110 odds.

A +37.5 Eastern Kentucky underdog bet wins if they lose by 37 or fewer, tie, or win outright. Your bet loses if they lose by 38 or more.

Favorite Louisville - Louisville bettors risk $100 to win $90.91 at -110 odds.

A -37.5 Louisville favorite bet wins if they win by 38 or more. Your bet loses if they win by 37 or fewer, tie, or lose outright.

Eastern Kentucky at Louisville Prop Bets

Important Note: Some states expressly forbid individual college athlete prop bets. The following wagers may not be available depending on your particular state laws.

College Football Prop Bets
+ Displays more odds
BetMGM Sports Betting BetMGM
Bet
Eastern Kentucky
Louisville
8/30/25 3:00pm EDT
Pending BetMGM

Recent Meetings Since 2021

Recent Meetings Since 2021
WeekGameResultMargin
2021
Week 2
Eastern Kentucky vs Louisville
Saturday, September 11th, 2021
LOU 30, EKU 3
Cardinal Stadium
Louisville by 27

Team Standings

2025-2026 College Football Regular Season Standings - Eastern Kentucky, Louisville
Team Conf Conf% W L PF PA Home Away Strk
UAC
Eastern Kentucky0-00.00000000-00-0-
ACC
Louisville0-00.0001051171-00-0W1

Eastern Kentucky & Louisville Futures Odds

Latest NCAA Championship odds, if available, for each team. Review odds for other teams and learn the best College Football bets.

Eastern Kentucky Championship Odds

No NCAA College Football Championship TM Eastern Kentucky YR: futures available

Louisville Championship Odds
2025-26 Louisville NCAA College Football Championship Odds

Team
BetMGM Sports Betting BetMGM
Louisville
+8000
Bet

Eastern Kentucky & Louisville Team Pages

Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Schedules & Results


2025-26 Eastern Kentucky Games & Results
WeekMatchupDate & Result
Week 1Eastern Kentucky vs
Louisville
Saturday, August 30th, 2025
3:00 pm EDT
Week 3Eastern Kentucky vs
Marshall
Saturday, September 13th, 2025
6:00 pm EDT


2025-26 Louisville Games & Results
WeekMatchupDate & Result
Week 1Eastern Kentucky vs
Louisville
Saturday, August 30th, 2025
3:00 pm EDT
Week 2James Madison vs
Louisville
Friday, September 5th, 2025
7:00 pm EDT
Week 4Bowling Green vs
Louisville
Saturday, September 20th, 2025
12:00 am EDT
Week 5Louisville vs
Pittsburgh
Saturday, September 27th, 2025
12:00 am EDT
Week 6Virginia vs
Louisville
Saturday, October 4th, 2025
12:00 am EDT
Week 8Louisville vs
Miami (FL)
Friday, October 17th, 2025
7:00 pm EDT
Week 9Boston College vs
Louisville
Saturday, October 25th, 2025
12:00 am EDT
Week 10Louisville vs
Virginia Tech
Saturday, November 1st, 2025
12:00 am EDT
Week 11California vs
Louisville
Saturday, November 8th, 2025
12:00 am EST
Week 12Clemson vs
Louisville
Friday, November 14th, 2025
8:00 pm EST
Week 13Louisville vs
SMU
Saturday, November 22nd, 2025
12:00 am EST
Week 14Kentucky vs
Louisville
Saturday, November 29th, 2025
12:00 am EST

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Eastern Kentucky vs Louisville College Football Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Saturday, August 30th, 2025 at 3:00 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's College Football page, look for the Eastern Kentucky vs Louisville Game.

    Navigate to the sportsbook's College Football page. Next, look for live or upcoming matchups. Select the Eastern Kentucky vs Louisville Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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