The Colonels will play the Cardinals on Saturday, August 30th, 2025. The matchup takes place at L&N Federal Credit Union Stadium. Watch this exciting Week 1 matchup at 3:00 pm EDT. Check local listings for coverage on ACC Extra.
Learn more about College Football betting with our handy tutorial and guide. We explain spread, total and money line bets.
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Table of Contents
- Matchup Stats
- Paddy O'Parlay
- Best Odds
- Interactive Odds Example
- Prop Bets
- Recent Meetings
- Team Standings
- Futures Odds
- Team Pages
- Team Schedules & Results
- Other Games Today
Key Matchup Stats
The 2025 college football season has begun, with Eastern Kentucky and Louisville scheduled to matchup at L&N Federal Credit Union Stadium. First, let's review each team's stats from the 2024 season to get an idea of what we can expect on gameday.
- SportsBetting3.com Power Rankings - Eastern Kentucky had a 97.00 conference power ranking in the 2024 season. The conference power ranking for Louisville in the 2024 season was 98.00.
- Away Eastern Kentucky - At the end of the 2024 regular season, Eastern Kentucky had a 2-5 record as an away team, ranking them 4th in the UAC Conference for away team wins.
- Home Louisville - Louisville finished the 2024 regular season with a 4-2 record as a home team. They ranked 3rd in the ACC Conference for home team wins in 2024.
- Points Scored - Eastern Kentucky wound up 6th (291) in the UAC Conference, with Louisville ranked 4th (474) for points scored in the 2024 ACC Conference.
- Points Against - Eastern Kentucky finished 8th (308) in the UAC Conference for points scored by opponents in 2024. Louisville wound up 13th (313) in the 2024 ACC Conference for points against.
- Team Records - Eastern Kentucky had a 8-5 regular season overall record, with Louisville notching a 9-4 regular season standing last year.
Paddy O'Parlay
The "Sports Network" talking heads have nothing on my Irish arse!

Are you ready for some college football madness? Eastern Kentucky vs. Louisville, August 30th!
The battle begins at L&N Federal Credit Union Stadium, where the teams clash. Eastern Kentucky, with an 8-5 record, faces Louisville, standing at 9-4.
Expect a fierce showdown as these teams fight to kick off the season right. SportsBetting3.com has all the details - bet on this game and review the odds below. Let the games begin!
Best Colonels at Cardinals Odds
Underdog Eastern Kentucky | Favorite Louisville |
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Over | Under |
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TBD | TBD |
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Matchup Odds FAQs
Louisville is a -37.5 -110 point spread favorite at BetMGM, while Eastern Kentucky is a +37.5 -110 point spread underdog at BetMGM.
The best over line is 56.5 -110 points at BetMGM, which means you risk $110 to win $100 betting the over. The best under line is 56.5 -110 points at BetMGM, and that means you risk $110 to win $100 betting the under.
College Football Odds Example
Game |
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Eastern Kentucky
Louisville
8/30/25 3:00pm EDT | +37.5 -110-37.5 -110 |
Underdog Eastern Kentucky - Eastern Kentucky bettors risk $100 to win $90.91 at -110 odds.
A +37.5 Eastern Kentucky underdog bet wins if they lose by 37 or fewer, tie, or win outright. Your bet loses if they lose by 38 or more.
Favorite Louisville - Louisville bettors risk $100 to win $90.91 at -110 odds.
A -37.5 Louisville favorite bet wins if they win by 38 or more. Your bet loses if they win by 37 or fewer, tie, or lose outright.
Eastern Kentucky at Louisville Prop Bets
Important Note: Some states expressly forbid individual college athlete prop bets. The following wagers may not be available depending on your particular state laws.
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Eastern Kentucky
Louisville
8/30/25 3:00pm EDT | Pending BetMGM |
Recent Meetings Since 2021
Week | Game | Result | Margin |
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2025 Week 1 | Eastern Kentucky vs Louisville Saturday, August 30th, 2025 | LOU 51, EKU 17 L&N Federal Credit Union Stadium | Louisville by 34 |
2021 Week 2 | Eastern Kentucky vs Louisville Saturday, September 11th, 2021 | LOU 30, EKU 3 Cardinal Stadium | Louisville by 27 |
Team Standings
Team | Conf | Conf% | W | L | PF | PA | Home | Away | Strk |
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UAC | |||||||||
Eastern Kentucky | 1-2 | 0.333 | 3 | 4 | 131 | 194 | 3-0 | 0-4 | L1 |
ACC | |||||||||
Louisville | 2-1 | 0.667 | 5 | 1 | 204 | 126 | 3-1 | 2-0 | W1 |
Eastern Kentucky & Louisville Futures Odds
Latest NCAA Championship odds, if available, for each team. Review odds for other teams and learn the best College Football bets.
Eastern Kentucky Championship OddsNo NCAA College Football Championship TM Eastern Kentucky YR: futures available
Louisville Championship Odds
Team | ![]() |
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Louisville | +15000 Bet |
Eastern Kentucky & Louisville Team Pages
Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:
Team Schedules & Results
Week | Matchup | Date & Result |
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Week 1 | Eastern Kentucky vs Louisville | LOU 51, EKU 17 Saturday, August 30th, 2025 |
Week 3 | Eastern Kentucky vs Marshall | MRSH 38, EKU 7 Saturday, September 13th, 2025 |
Week | Matchup | Date & Result |
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Week 1 | Eastern Kentucky vs Louisville | LOU 51, EKU 17 Saturday, August 30th, 2025 |
Week 2 | James Madison vs Louisville | LOU 28, JMU 14 Friday, September 5th, 2025 |
Week 4 | Bowling Green vs Louisville | LOU 40, BGSU 17 Saturday, September 20th, 2025 |
Week 5 | Louisville vs Pittsburgh | LOU 34, PITT 27 Saturday, September 27th, 2025 |
Week 6 | Virginia vs Louisville | UVA 30, LOU 27 (OT) Saturday, October 4th, 2025 |
Week 8 | Louisville vs Miami (FL) | LOU 24, MIA 21 Friday, October 17th, 2025 |
Week 9 | Boston College vs Louisville | Saturday, October 25th, 2025 7:30 pm EDT |
Week 10 | Louisville vs Virginia Tech | Saturday, November 1st, 2025 12:00 am EDT |
Week 11 | California vs Louisville | Saturday, November 8th, 2025 12:00 am EST |
Week 12 | Clemson vs Louisville | Friday, November 14th, 2025 7:30 pm EST |
Week 13 | Louisville vs SMU | Saturday, November 22nd, 2025 12:00 am EST |
Week 14 | Kentucky vs Louisville | Saturday, November 29th, 2025 12:00 am EST |
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the Eastern Kentucky vs Louisville College Football Game
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Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Saturday, August 30th, 2025 at 3:00 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
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Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
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Tap to the sportsbook's College Football page, look for the Eastern Kentucky vs Louisville Game.
Navigate to the sportsbook's College Football page. Next, look for live or upcoming matchups. Select the Eastern Kentucky vs Louisville Game.
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Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.
Other August 30, 2025 NCAAFB Games
- Tennessee vs Syracuse
- Richmond vs Lehigh
- Mississippi State vs Southern Miss
- Ball State vs Purdue
- North Dakota State vs The Citadel
- Duquesne vs Pittsburgh
- Florida Atlantic vs Maryland
- VMI vs Navy
- Northwestern vs Tulane
- Texas vs Ohio State
- Merrimack College vs Kent State
- Toledo vs Kentucky
- Butler vs Northern Iowa
- William & Mary vs Furman
- Fordham vs Boston College
- Central Connecticut vs UConn
- Robert Morris vs West Virginia
- Old Dominion vs Indiana
- Hampton vs Jackson State
- Nevada vs Penn State
- Bucknell vs Air Force
- Holy Cross vs Northern Illinois
- Temple vs UMass
- Marshall vs Georgia
- Alabama vs Florida State
- South Dakota vs Iowa State
- Maine vs Liberty
- Howard vs Florida A&M
- Montana State vs Oregon
- Alabama A&M vs Arkansas
- North Carolina A&T vs Tennessee State
- Chattanooga vs Memphis
- Southern vs Miss Valley State
- Murray State vs East Tennessee State
- Albany vs Iowa
- Stonehill vs Sacred Heart
- Gardner-Webb vs Western Carolina
- New Hampshire vs North Carolina Central
- Presbyterian vs Mercer
- Coastal Carolina vs Virginia
- Wofford vs South Carolina State
- Illinois State vs Oklahoma
- Weber State vs James Madison
- Sacramento State vs South Dakota State
- Eastern Washington vs Incarnate Word
- Southeast Missouri State vs Arkansas State
- Austin Peay vs Middle Tennessee
- Morgan State vs South Alabama
- North Alabama vs Western Kentucky
- North Dakota vs Kansas State
- Nicholls vs Troy
- UTSA vs Texas A&M
- Charleston Southern vs Vanderbilt
- Long Island University vs Florida
- LIU vs Florida
- New Mexico vs Michigan
- LSU vs Clemson
- UTEP vs Utah State
- Arkansas-Pine Bluff vs Texas Tech
- Missouri State vs USC
- Southeastern Louisiana vs Louisiana Tech
- Georgia State vs Ole Miss
- Cal Poly vs San Diego
- Prairie View A&M vs Texas Southern
- Portland State vs BYU
- Rice vs Louisiana
- Eastern Michigan vs Texas State
- Abilene Christian vs Tulsa
- Lamar vs North Texas
- Idaho State vs Southern Utah
- Bryant vs New Mexico State
- East Texas A&M vs SMU
- Georgia Southern vs Fresno State
- Idaho vs Washington State
- Northern Arizona vs Arizona State
- UC Davis vs Utah Tech
- California vs Oregon State
- Hawaii vs Arizona
- Colorado State vs Washington
- Utah vs UCLA