The Colonels will play the Cardinals on Saturday, September 11th, 2021. The matchup takes place at Cardinal Stadium. Watch this exciting Week 2 matchup at 7:00 pm EDT. Check local listings for coverage on ACCNX, ESPN+.
Learn more about College Football betting with our handy tutorial and guide. We explain spread, total and money line bets.
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Table of Contents
- Best Odds
- Interactive Odds Example
- Prop Bets
- Recent Meetings
- Team Standings
- Futures Odds
- Team Schedules & Results
- Other Games Today
Best Colonels at Cardinals Odds
| Underdog | Favorite |
|---|
| Over | Under |
|---|
| Underdog | Favorite |
|---|
College Football Odds Example
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Game |
Bet |
|---|---|
11:30pm EDT | TBD VA |
No VA Point Spread lines available for this game.
Eastern Kentucky at Louisville Prop Bets
Important Note: Some states expressly forbid individual college athlete prop bets. The following wagers may not be available depending on your particular state laws.
 BetRiversBet |
|
|---|---|
Eastern Kentucky
Louisville
9/11/21 7:00pm EDT | Pending BetRivers |
Recent Meetings Since 2017
| Week | Game | Result | Margin |
|---|---|---|---|
| 2021 Week 2 | Eastern Kentucky vs Louisville Saturday, September 11th, 2021 | LOU 30, EKU 3 Cardinal Stadium | Louisville by 27 |
Team Standings
| Team | Conf | Conf% | W | L | PF | PA | Home | Away | Strk |
|---|---|---|---|---|---|---|---|---|---|
| ASUN-WAC | |||||||||
| Eastern Kentucky | 4-2 | 0.667 | 7 | 4 | 304 | 275 | 5-1 | 2-3 | W1 |
| ACC Atlantic | |||||||||
| Louisville | 4-4 | 0.500 | 6 | 7 | 411 | 355 | 4-3 | 2-2 | L2 |
Eastern Kentucky & Louisville Futures Odds
Latest NCAA Championship odds, if available, for each team. Review odds for other teams and learn the best College Football bets here.
Eastern Kentucky Championship OddsNo NCAA College Football Championship TM Eastern Kentucky YR: futures available
Louisville Championship Odds|
Team | BetRivers |
 BetMGM |
|---|---|---|
| Louisville |
Team Schedules & Results
| Week | Matchup | Date & Result |
|---|---|---|
| Week 2 | Eastern Kentucky vs Louisville | LOU 30, EKU 3 Saturday, September 11th, 2021 |
| Week | Matchup | Date & Result |
|---|---|---|
| Week 1 | Louisville vs Ole Miss | MISS 43, LOU 24 Monday, September 6th, 2021 |
| Week 2 | Eastern Kentucky vs Louisville | LOU 30, EKU 3 Saturday, September 11th, 2021 |
| Week 3 | UCF vs Louisville | LOU 42, UCF 35 Friday, September 17th, 2021 |
| Week 4 | Louisville vs Florida State | LOU 31, FSU 23 Saturday, September 25th, 2021 |
| Week 5 | Louisville vs Wake Forest | WAKE 37, LOU 34 Saturday, October 2nd, 2021 |
| Week 6 | Virginia vs Louisville | UVA 34, LOU 33 Saturday, October 9th, 2021 |
| Week 8 | Boston College vs Louisville | LOU 28, BC 14 Saturday, October 23rd, 2021 |
| Week 9 | Louisville vs NC State | NCST 28, LOU 13 Saturday, October 30th, 2021 |
| Week 10 | Clemson vs Louisville | CLEM 30, LOU 24 Saturday, November 6th, 2021 |
| Week 11 | Syracuse vs Louisville | LOU 41, SYR 3 Saturday, November 13th, 2021 |
| Week 12 | Louisville vs Duke | LOU 62, DUKE 22 Thursday, November 18th, 2021 |
| Week 13 | Kentucky vs Louisville | UK 52, LOU 21 Saturday, November 27th, 2021 |
| Bowls | Air Force vs Louisville Servpro First Responder Bowl | AFA 31, LOU 28 Tuesday, December 28th, 2021 |
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the Eastern Kentucky vs Louisville College Football Game
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Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Saturday, September 11th, 2021 at 7:00 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
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Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
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Tap to the sportsbook's College Football page, look for the Eastern Kentucky vs Louisville Game.
Navigate to the sportsbook's College Football page. Next, look for live or upcoming matchups. Select the Eastern Kentucky vs Louisville Game.
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Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.