Louisville vs Duke Football Odds

The Cardinals will play the Blue Devils on Thursday, November 18th, 2021. The matchup takes place at Wallace Wade Stadium - Durham, NC. Watch this exciting Week 12 matchup at 7:30 pm EST. Check local listings for coverage on ESPN.

Learn more about College Football betting with our handy tutorial and guide. We explain spread, total and money line bets. Read the following to understand point spread betting.


Point Spread
Underdog

Favorite

Point Spread odds are updating, please check back soon.

Total
OverUnder
Total odds are updating, please check back soon.

Moneyline
Underdog

Favorite

Moneyline odds are updating, please check back soon.

Recent Meetings Since 2017

WeekGameResultMargin
2021
Wk 12
Louisville vs Duke
Thursday, November 18th, 2021
LOU 62, DUKE 22
Wallace Wade Stadium - Durham, NC
Louisville by 40

College Football Championship Odds

Latest NCAA Championship odds, if available, for each team. Review odds for other teams and learn the best College Football bets here.

Louisville Championship Odds
2023 NCAA College Football Championship Odds

Team
BetRivers BetRivers
Louisville
Duke Championship Odds
2023 NCAA College Football Championship Odds

Team
BetRivers BetRivers
Duke

2021 Louisville Games & Results

WeekMatchupDate & Time
1Louisville vs
Ole Miss
Chick-Fil-A Kickoff Game
MISS 43, LOU 24
Monday, September 6th, 2021
2Eastern Kentucky vs
Louisville
LOU 30, EKU 3
Saturday, September 11th, 2021
3UCF vs
Louisville
LOU 42, UCF 35
Friday, September 17th, 2021
4Louisville vs
Florida State
LOU 31, FSU 23
Saturday, September 25th, 2021
5Louisville vs
Wake Forest
WAKE 37, LOU 34
Saturday, October 2nd, 2021
6Virginia vs
Louisville
UVA 34, LOU 33
Saturday, October 9th, 2021
8Boston College vs
Louisville
LOU 28, BC 14
Saturday, October 23rd, 2021
9Louisville vs
NC State
NCST 28, LOU 13
Saturday, October 30th, 2021
10Clemson vs
Louisville
CLEM 30, LOU 24
Saturday, November 6th, 2021
11Syracuse vs
Louisville
LOU 41, SYR 3
Saturday, November 13th, 2021
12Louisville vs
Duke
LOU 62, DUKE 22
Thursday, November 18th, 2021
13Kentucky vs
Louisville
UK 52, LOU 21
Saturday, November 27th, 2021
1Air Force vs
Louisville
Servpro First Responder Bowl
AFA 31, LOU 28
Tuesday, December 28th, 2021

2021 Duke Games & Results

WeekMatchupDate & Time
1Duke vs
Charlotte
CLT 31, DUKE 28
Friday, September 3rd, 2021
2North Carolina A&T vs
Duke
DUKE 45, NCAT 17
Friday, September 10th, 2021
3Northwestern vs
Duke
DUKE 30, NU 23
Saturday, September 18th, 2021
4Kansas vs
Duke
DUKE 52, KU 33
Saturday, September 25th, 2021
5Duke vs
North Carolina
UNC 38, DUKE 7
Saturday, October 2nd, 2021
6Georgia Tech vs
Duke
GT 31, DUKE 27
Saturday, October 9th, 2021
7Duke vs
Virginia
UVA 48, DUKE 0
Saturday, October 16th, 2021
9Duke vs
Wake Forest
WAKE 45, DUKE 7
Saturday, October 30th, 2021
10Pittsburgh vs
Duke
PITT 54, DUKE 29
Saturday, November 6th, 2021
11Duke vs
Virginia Tech
VT 48, DUKE 17
Saturday, November 13th, 2021
12Louisville vs
Duke
LOU 62, DUKE 22
Thursday, November 18th, 2021
13Miami (FL) vs
Duke
MIA 47, DUKE 10
Saturday, November 27th, 2021

Current College Football Lines

Next 20 NCAAFB Matchups
+ Displays more odds

Game
BetRivers BetRivers
Play
Nebraska
Northwestern
8/27/22 12:00pm EDT
Charlotte
Florida Atlantic
8/27/22 1:00pm EDT
Vanderbilt
Hawaii
8/27/22 1:00pm EDT
Wyoming
Illinois
8/27/22 1:00pm EDT
Nevada
New Mexico State
8/27/22 1:00pm EDT
North Texas
UTEP
8/27/22 1:00pm EDT
UConn
Utah State
8/27/22 1:00pm EDT
West Virginia
Pittsburgh
9/01/22 12:00pm EDT
Penn State
Purdue
9/01/22 12:00pm EDT
Central Michigan
Oklahoma State
9/01/22 1:00pm EDT
New Mexico State
Minnesota
9/01/22 1:00pm EDT
TCU
Colorado
9/02/22 12:00pm EDT
Illinois
Indiana
9/02/22 12:00pm EDT
Western Michigan
Michigan State
9/02/22 12:00pm EDT
Temple
Duke
9/02/22 1:00pm EDT
Virginia Tech
Old Dominion
9/02/22 1:00pm EDT
North Carolina
Appalachian State
9/03/22 12:00pm EDT
Notre Dame
Ohio State
9/03/22 12:00pm EDT
Memphis
Mississippi State
9/03/22 12:00pm EDT
Colorado State
Michigan
9/03/22 12:00pm EDT
Odds Preview 2230