Louisville vs Duke Football Odds

The Cardinals will play the Blue Devils on Thursday, November 18th, 2021. The matchup takes place at Wallace Wade Stadium. Watch this exciting Week 12 matchup at 7:30 pm EST. Check local listings for coverage on ESPN.

Learn more about College Football betting with our handy tutorial and guide. We explain spread, total and money line bets. Read the following to understand point spread betting.

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Point Spread
Underdog

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Total
OverUnder
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Moneyline
Underdog

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College Football Odds Example

College Football Odds and Outcomes Explained

Game

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2:44pm EDT
TBD VA
VA Odds Pending
No VA Point Spread lines available for this game.

Louisville at Duke Prop Bets

Important Note: Some states expressly forbid individual college athlete prop bets. The following wagers may not be available depending on your particular state laws.

College Football Prop Bets
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Louisville
Duke
11/18/21 7:30pm EST
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Recent Meetings Since 2017

Recent Meetings Since 2017
WeekGameResultMargin
2021
Week 12
Louisville vs Duke
Thursday, November 18th, 2021
LOU 62, DUKE 22
Wallace Wade Stadium
Louisville by 40

Team Season Win Totals

The following are each team's season win totals. Learn more about season win totals.

Louisville Season Win Total
2023 College Football Louisville Season Win Total
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Louisville
2023 Season Win Total
Duke Season Win Total
2023 College Football Duke Season Win Total
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Duke
2023 Season Win Total

College Football Championship Odds

Latest NCAA Championship odds, if available, for each team. Review odds for other teams and learn the best College Football bets here.

Louisville Championship Odds
2024 Louisville NCAA College Football Championship Odds

Team
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Louisville
Duke Championship Odds
2024 Duke NCAA College Football Championship Odds

Team
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Duke

Team Standings

2021-2022 College Football Standings - Louisville, Duke
Team Conf Conf% W L PF PA Home Away Strk
ACC Atlantic
Louisville4-40.500674113554-32-2L2
ACC Coastal
Duke0-80.000392744773-40-5L8

2021-22 Louisville Games & Results

2021-22 Louisville Games & Results
WeekMatchupDate & Time
Week 1Louisville vs
Ole Miss
MISS 43, LOU 24
Monday, September 6th, 2021
Week 2Eastern Kentucky vs
Louisville
LOU 30, EKU 3
Saturday, September 11th, 2021
Week 3UCF vs
Louisville
LOU 42, UCF 35
Friday, September 17th, 2021
Week 4Louisville vs
Florida State
LOU 31, FSU 23
Saturday, September 25th, 2021
Week 5Louisville vs
Wake Forest
WAKE 37, LOU 34
Saturday, October 2nd, 2021
Week 6Virginia vs
Louisville
UVA 34, LOU 33
Saturday, October 9th, 2021
Week 8Boston College vs
Louisville
LOU 28, BC 14
Saturday, October 23rd, 2021
Week 9Louisville vs
NC State
NCST 28, LOU 13
Saturday, October 30th, 2021
Week 10Clemson vs
Louisville
CLEM 30, LOU 24
Saturday, November 6th, 2021
Week 11Syracuse vs
Louisville
LOU 41, SYR 3
Saturday, November 13th, 2021
Week 12Louisville vs
Duke
LOU 62, DUKE 22
Thursday, November 18th, 2021
Week 13Kentucky vs
Louisville
UK 52, LOU 21
Saturday, November 27th, 2021
BowlsAir Force vs
Louisville
Servpro First Responder Bowl
AFA 31, LOU 28
Tuesday, December 28th, 2021

2021-22 Duke Games & Results

2021-22 Duke Games & Results
WeekMatchupDate & Time
Week 1Duke vs
Charlotte
CLT 31, DUKE 28
Friday, September 3rd, 2021
Week 2North Carolina A&T vs
Duke
DUKE 45, NCAT 17
Friday, September 10th, 2021
Week 3Northwestern vs
Duke
DUKE 30, NU 23
Saturday, September 18th, 2021
Week 4Kansas vs
Duke
DUKE 52, KU 33
Saturday, September 25th, 2021
Week 5Duke vs
North Carolina
UNC 38, DUKE 7
Saturday, October 2nd, 2021
Week 6Georgia Tech vs
Duke
GT 31, DUKE 27
Saturday, October 9th, 2021
Week 7Duke vs
Virginia
UVA 48, DUKE 0
Saturday, October 16th, 2021
Week 9Duke vs
Wake Forest
WAKE 45, DUKE 7
Saturday, October 30th, 2021
Week 10Pittsburgh vs
Duke
PITT 54, DUKE 29
Saturday, November 6th, 2021
Week 11Duke vs
Virginia Tech
VT 48, DUKE 17
Saturday, November 13th, 2021
Week 12Louisville vs
Duke
LOU 62, DUKE 22
Thursday, November 18th, 2021
Week 13Miami (FL) vs
Duke
MIA 47, DUKE 10
Saturday, November 27th, 2021

Other November 18, 2021 NCAAFB Games

Matchup
Nicholls vs
Southeastern Louisiana
Odds Preview 2230