Louisville vs Duke Football Odds

The Cardinals will play the Blue Devils on Thursday, November 18th, 2021. The matchup takes place at Wallace Wade Stadium - Durham, NC. Watch this exciting Week 12 matchup at 7:30 pm EST. Check local listings for coverage on ESPN.

Learn more about College Football betting with our handy tutorial and guide. We explain spread, total and money line bets. Read the following to understand point spread betting.

**Point Spread**
Underdog	Favorite

Point Spread odds are updating, please check back soon.

**Total**
Over	Under

Total odds are updating, please check back soon.

**Moneyline**
Underdog	Favorite

Moneyline odds are updating, please check back soon.

Recent Meetings Since 2017

Week	Game	Result	Margin
2021 Wk 12	Louisville vs Duke Thursday, November 18th, 2021	LOU 62, DUKE 22 Wallace Wade Stadium - Durham, NC	Louisville by 40

College Football Championship Odds

Latest NCAA Championship odds, if available, for each team. Review odds for other teams and learn the best College Football bets here.

Louisville Championship Odds

2023 NCAA College Football Championship Odds
Team	BetRivers
Louisville	+20000 Play

Duke Championship Odds

2023 NCAA College Football Championship Odds
Team	BetRivers
Duke	+100000 Play

2021 Louisville Games & Results

Week	Matchup	Date & Time
1	Louisville vs Ole Miss Chick-Fil-A Kickoff Game	MISS 43, LOU 24 Monday, September 6th, 2021
2	Eastern Kentucky vs Louisville	LOU 30, EKU 3 Saturday, September 11th, 2021
3	UCF vs Louisville	LOU 42, UCF 35 Friday, September 17th, 2021
4	Louisville vs Florida State	LOU 31, FSU 23 Saturday, September 25th, 2021
5	Louisville vs Wake Forest	WAKE 37, LOU 34 Saturday, October 2nd, 2021
6	Virginia vs Louisville	UVA 34, LOU 33 Saturday, October 9th, 2021
8	Boston College vs Louisville	LOU 28, BC 14 Saturday, October 23rd, 2021
9	Louisville vs NC State	NCST 28, LOU 13 Saturday, October 30th, 2021
10	Clemson vs Louisville	CLEM 30, LOU 24 Saturday, November 6th, 2021
11	Syracuse vs Louisville	LOU 41, SYR 3 Saturday, November 13th, 2021
12	Louisville vs Duke	LOU 62, DUKE 22 Thursday, November 18th, 2021
13	Kentucky vs Louisville	UK 52, LOU 21 Saturday, November 27th, 2021
1	Air Force vs Louisville Servpro First Responder Bowl	AFA 31, LOU 28 Tuesday, December 28th, 2021

2021 Duke Games & Results

Week	Matchup	Date & Time
1	Duke vs Charlotte	CLT 31, DUKE 28 Friday, September 3rd, 2021
2	North Carolina A&T vs Duke	DUKE 45, NCAT 17 Friday, September 10th, 2021
3	Northwestern vs Duke	DUKE 30, NU 23 Saturday, September 18th, 2021
4	Kansas vs Duke	DUKE 52, KU 33 Saturday, September 25th, 2021
5	Duke vs North Carolina	UNC 38, DUKE 7 Saturday, October 2nd, 2021
6	Georgia Tech vs Duke	GT 31, DUKE 27 Saturday, October 9th, 2021
7	Duke vs Virginia	UVA 48, DUKE 0 Saturday, October 16th, 2021
9	Duke vs Wake Forest	WAKE 45, DUKE 7 Saturday, October 30th, 2021
10	Pittsburgh vs Duke	PITT 54, DUKE 29 Saturday, November 6th, 2021
11	Duke vs Virginia Tech	VT 48, DUKE 17 Saturday, November 13th, 2021
12	Louisville vs Duke	LOU 62, DUKE 22 Thursday, November 18th, 2021
13	Miami (FL) vs Duke	MIA 47, DUKE 10 Saturday, November 27th, 2021

Current College Football Lines

Next 20 NCAAFB Matchups
+ Displays more odds
Game	BetRivers Play
Nebraska Northwestern 8/27/22 12:00pm EDT	-12.5 -110 +12.5 -110
Charlotte Florida Atlantic 8/27/22 1:00pm EDT	+7.5 -112 -7.5 -109
Vanderbilt Hawaii 8/27/22 1:00pm EDT	-6.5 -117 +6.5 -105
Wyoming Illinois 8/27/22 1:00pm EDT	+11 -110 -11 -110
Nevada New Mexico State 8/27/22 1:00pm EDT	-13.5 -121 +13.5 +100
North Texas UTEP 8/27/22 1:00pm EDT	-2 -113 +2 -108
UConn Utah State 8/27/22 1:00pm EDT	+27.5 -110 -27.5 -110
West Virginia Pittsburgh 9/01/22 12:00pm EDT	+6.5 -103 -6.5 -118
Penn State Purdue 9/01/22 12:00pm EDT	-3.5 -110 +3.5 -110
Central Michigan Oklahoma State 9/01/22 1:00pm EDT	+20.5 -103 -20.5 -120
New Mexico State Minnesota 9/01/22 1:00pm EDT	+38.5 -113 -38.5 -108
TCU Colorado 9/02/22 12:00pm EDT	-7.5 +100 +7.5 -122
Illinois Indiana 9/02/22 12:00pm EDT	+5.5 -110 -5.5 -110
Western Michigan Michigan State 9/02/22 12:00pm EDT	+18.5 -110 -18.5 -110
Temple Duke 9/02/22 1:00pm EDT	+8 -109 -8 -112
Virginia Tech Old Dominion 9/02/22 1:00pm EDT	-8.5 -110 +8.5 -110
North Carolina Appalachian State 9/03/22 12:00pm EDT	-3.5 -110 +3.5 -110
Notre Dame Ohio State 9/03/22 12:00pm EDT	+14.5 -112 -14.5 -109
Memphis Mississippi State 9/03/22 12:00pm EDT	+16.5 -110 -16.5 -110
Colorado State Michigan 9/03/22 12:00pm EDT	+27.5 -104 -27.5 -118

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