The Cardinals will play the Orange on Saturday, September 3rd, 2022. The matchup takes place at JMA Wireless Dome. Watch this exciting Week 1 matchup at 8:00 pm EDT. Check local listings for coverage on ACCN.
Learn more about College Football betting with our handy tutorial and guide. We explain spread, total and money line bets.
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Table of Contents
- Best Odds
- Interactive Odds Example
- Prop Bets
- Recent Meetings
- Team Standings
- Futures Odds
- Team Schedules & Results
- Other Games Today
Best Cardinals at Orange Odds
| Underdog Syracuse | Favorite Louisville |
|---|---|
| Over | Under |
|---|---|
| Underdog Syracuse | Favorite Louisville |
|---|---|
Matchup Odds FAQs
Louisville is a -6 +100 point spread favorite at BetRivers, while Syracuse is a +6 -121 point spread underdog at BetRivers.
The best over line is 55.5 -109 points at BetRivers, which means you risk $109 to win $100 betting the over. The best under line is 55.5 -112 points at BetRivers, and that means you risk $112 to win $100 betting the under.
Louisville is a -215 moneyline favorite at BetRivers and Syracuse is a +170 moneyline underdog at BetRivers.
College Football Odds Example
|
Game |
 BetRiversBet |
|---|---|
Louisville
Syracuse
9/03/22 8:00pm EDT | -6 +100+6 -121 |
Underdog Syracuse - Syracuse bettors risk $100 to win $82.64 at -121 odds.
A +6 Syracuse underdog bet wins if they lose by 5 or fewer, tie, or win outright. The bet pushes if they lose by 6. Your bet loses if they lose by 7 or more.
Favorite Louisville - Louisville bettors risk $100 to win $100 at +100 odds.
A -6 Louisville favorite bet wins if they win by 7 or more. The bet pushes if they win by 6. Your bet loses if they win by 5 or fewer, tie, or lose outright.
Louisville at Syracuse Prop Bets
Important Note: Some states expressly forbid individual college athlete prop bets. The following wagers may not be available depending on your particular state laws.
 BetMGMBet |
|
|---|---|
Louisville
Syracuse
9/03/22 8:00pm EDT | Pending BetMGM |
Recent Meetings Since 2018
| Week | Game | Result | Margin |
|---|---|---|---|
| 2022 Week 1 | Louisville vs Syracuse Saturday, September 3rd, 2022 | SYR 31, LOU 7 JMA Wireless Dome | Syracuse by 24 |
| 2021 Week 11 | Syracuse vs Louisville Saturday, November 13th, 2021 | LOU 41, SYR 3 Cardinal Stadium | Louisville by 38 |
| 2019 Week 13 | Syracuse vs Louisville Saturday, November 23rd, 2019 | LOU 56, SYR 34 Cardinal Stadium | Louisville by 22 |
| 2018 Week 11 | Louisville vs Syracuse Friday, November 9th, 2018 | SYR 54, LOU 23 JMA Wireless Dome | Syracuse by 31 |
Team Standings
| Team | Conf | Conf% | W | L | PF | PA | Home | Away | Strk |
|---|---|---|---|---|---|---|---|---|---|
| Louisville | 4-4 | 0.500 | 8 | 5 | 350 | 249 | 5-1 | 2-4 | W1 |
| Syracuse | 4-4 | 0.500 | 7 | 6 | 360 | 300 | 5-2 | 2-3 | L1 |
Louisville & Syracuse Futures Odds
Latest NCAA Championship odds, if available, for each team. Review odds for other teams and learn the best College Football bets.
Louisville Championship Odds|
Team | BetMGM |
BetRivers |
|---|---|---|
| Louisville | +10000 Bet | +10000 Bet |
|
Team | BetMGM |
BetRivers |
|---|---|---|
| Syracuse | +80000 Bet |
Team Schedules & Results
| Week | Matchup | Date & Result |
|---|---|---|
| Week 1 | Louisville vs Syracuse | SYR 31, LOU 7 Saturday, September 3rd, 2022 |
| Week 2 | Louisville vs UCF | LOU 20, UCF 14 Friday, September 9th, 2022 |
| Week 3 | Florida State vs Louisville | FSU 35, LOU 31 Friday, September 16th, 2022 |
| Week 4 | South Florida vs Louisville | LOU 41, USF 3 Saturday, September 24th, 2022 |
| Week 5 | Louisville vs Boston College | BC 34, LOU 33 Saturday, October 1st, 2022 |
| Week 6 | Louisville vs Virginia | LOU 34, UVA 17 Saturday, October 8th, 2022 |
| Week 8 | Pittsburgh vs Louisville | LOU 24, PITT 10 Saturday, October 22nd, 2022 |
| Week 9 | Wake Forest vs Louisville | LOU 48, WAKE 21 Saturday, October 29th, 2022 |
| Week 10 | James Madison vs Louisville | LOU 34, JMU 10 Saturday, November 5th, 2022 |
| Week 11 | Louisville vs Clemson | CLEM 31, LOU 16 Saturday, November 12th, 2022 |
| Week 12 | NC State vs Louisville | LOU 25, NCST 10 Saturday, November 19th, 2022 |
| Week 13 | Louisville vs Kentucky | UK 26, LOU 13 Saturday, November 26th, 2022 |
| Bowls | Cincinnati vs Louisville Wasabi Fenway Bowl | LOU 24, CIN 7 Saturday, December 17th, 2022 |
| Week | Matchup | Date & Result |
|---|---|---|
| Week 1 | Louisville vs Syracuse | SYR 31, LOU 7 Saturday, September 3rd, 2022 |
| Week 2 | Syracuse vs UConn | SYR 48, CONN 14 Saturday, September 10th, 2022 |
| Week 3 | Purdue vs Syracuse | SYR 32, PUR 29 Saturday, September 17th, 2022 |
| Week 4 | Virginia vs Syracuse | SYR 22, UVA 20 Friday, September 23rd, 2022 |
| Week 5 | Wagner vs Syracuse | SYR 59, WAG 0 Saturday, October 1st, 2022 |
| Week 7 | NC State vs Syracuse | SYR 24, NCST 9 Saturday, October 15th, 2022 |
| Week 8 | Syracuse vs Clemson | CLEM 27, SYR 21 Saturday, October 22nd, 2022 |
| Week 9 | Notre Dame vs Syracuse | ND 41, SYR 24 Saturday, October 29th, 2022 |
| Week 10 | Syracuse vs Pittsburgh | PITT 19, SYR 9 Saturday, November 5th, 2022 |
| Week 11 | Florida State vs Syracuse | FSU 38, SYR 3 Saturday, November 12th, 2022 |
| Week 12 | Syracuse vs Wake Forest | WAKE 45, SYR 35 Saturday, November 19th, 2022 |
| Week 13 | Syracuse vs Boston College | SYR 32, BC 23 Saturday, November 26th, 2022 |
| Bowls | Syracuse vs Minnesota Bad Boy Mowers Pinstripe Bowl | MINN 28, SYR 20 Thursday, December 29th, 2022 |
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the Louisville vs Syracuse College Football Game
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Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Saturday, September 3rd, 2022 at 8:00 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
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Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
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Tap to the sportsbook's College Football page, look for the Louisville vs Syracuse Game.
Navigate to the sportsbook's College Football page. Next, look for live or upcoming matchups. Select the Louisville vs Syracuse Game.
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Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.