Louisville vs USC Football Odds

The Cardinals will play the Trojans on Wednesday, December 27th, 2023, in the annual Directv Holiday Bowl event. The matchup takes place at Petco Park. Check local listings for coverage on FOX.

Learn more about College Football betting with our handy tutorial and guide. We explain spread, total and money line bets.


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Table of Contents

Key Matchup Stats

The college football bowls have arrived, with Louisville and USC scheduled to play at the 2023 Directv Holiday Bowl held at Petco Park. Be sure to bet before the game kicks off on Wednesday, December 27th, 2023. Carefully review how each team has played this season before placing a bet. We've compiled some key performance stats for each team from the 2023 college football regular season below.

  • SportsBetting3.com Power Rankings - At the conclusion of the 2023 regular season, Louisville had a 97.67 ACC Conference conference power ranking. Their Directv Holiday Bowl opponent, USC, had a 95.00 Pac-12 Conference power ranking.
  • Away Louisville - Heading into this bowl game, Louisville has a 2-1 record as an away team. This ranked them 4th in the ACC Conference for away team wins in 2023.
  • Home USC - USC has a 4-3 record as a home team for 2023. They finished the regular season ranked 4th in the Pac-12 Conference for home team wins.
  • Points Scored - At the end of the 2023 regular season, Louisville ranked 3rd (402) in the ACC Conference, with USC winding up 2nd (502) for points scored in the Pac-12 Conference.
  • Points Against - Louisville comes to this bowl game ranked 10th (256) in the ACC Conference for points scored by opponents in the 2023 college football season. Meanwhile, USC ranked 3rd (419) in the Pac-12 Conference for points against them during the 2023 college football season.
  • Team Records - Louisville finished the 2023 regular season with a 10-3 overall record, with USC tallying a 7-5 standing.

Paddy O'Parlay

The "Sports Network" talking heads have nothing on my Irish arse!

Paddy O'Parlay
Paddy O'Parlay

Get ready for a wild and wacky showdown as the Louisville Cardinals take on the USC Trojans! This explosive clash is set to unfold at Petco Park on December 27, 2023, in the Directv Holiday Bowl game. Brace yourself for a thrilling battle of talent and strategy!

When it comes to the SportsBetting3.com Power Rankings, Louisville brings a fiery 97.67, while USC boasts a solid 95.00. These teams are sure to put on a spectacular show, leaving fans on the edge of their seats throughout the game.

Louisville ended the regular season with an impressive 10-3 standing, showcasing their strength and determination. On the other hand, USC finished with a respectable 7-5 standing, proving they have what it takes to compete at a high level.

If you're looking to amp up the excitement, we recommend placing a bowl game wager at BetWay, BetMGM, or BetRivers. Compare the best point spread, total, and moneylines from our partner sportsbooks below and make the most out of this thrilling matchup. Don't miss out on one of your last chances to bet on 2023 college football!

So grab your lucky charms and get ready to witness a clash of titans at the Petco Park this December 27th. The Louisville Cardinals and USC Trojans are geared up to deliver a game for the ages. Buckle up, sports fans! It's going to be one epic battle!

Best Cardinals at Trojans Odds


Best Point Spread Betting Odds
Underdog

USC
Favorite

Louisville
Louisville has a -4.5 -110 point spread at BetMGM VA. They are the point spread favorite in this matchup. USC has a +4.5 -110 point spread at BetMGM VA. USC is the point spread underdog. Review how to bet on a point spread with our text and video tutorials.

Best Total Betting Odds
OverUnder
BetMGM has the best over line of 58 points. Risk $110 to win $100. BetMGM has the best under line of 58 points. Risk $110 to win $100. Our tutorial explains more about total bets.

Best Moneyline Betting Odds
Underdog

USC
Favorite

Louisville
Louisville is the -190 moneyline favorite. Risk $190 to win $100 on Louisville at BetMGM. USC is the +155 underdog at BetMGM. Risk $100 to win $155 on USC. Learn more about how to bet on money lines.

Matchup Odds FAQs

What is the point spread for the Louisville vs USC College Football game on Wednesday, December 27th, 2023?

Louisville is a -4.5 -110 point spread favorite at BetMGM, while USC is a +4.5 -110 point spread underdog at BetMGM.

What is the over-under total line for the Louisville vs USC College Football game on Wednesday, December 27th, 2023?

The best over line is 58 -110 points at BetMGM, which means you risk $110 to win $100 betting the over. The best under line is 58 -110 points at BetMGM, and that means you risk $110 to win $100 betting the under.

What is the moneyline for the Louisville vs USC College Football game on Wednesday, December 27th, 2023?

Louisville is a -190 moneyline favorite at BetMGM and USC is a +155 moneyline underdog at BetMGM.

College Football Odds Example

College Football Odds and Outcomes Explained

Game
BetMGM Sports Betting BetMGM
Bet
Louisville
USC
12/27/23 8:00pm EST
-4.5 -110+4.5 -110
Bet $100 at BetMGM Virginia
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Underdog USC - USC bettors risk $100 to win $90.91 at -110 odds.

A +4.5 USC underdog bet wins if they lose by 4 or fewer, tie, or win outright. Your bet loses if they lose by 5 or more.

Favorite Louisville - Louisville bettors risk $100 to win $90.91 at -110 odds.

A -4.5 Louisville favorite bet wins if they win by 5 or more. Your bet loses if they win by 4 or fewer, tie, or lose outright.

Louisville at USC Prop Bets

Important Note: Some states expressly forbid individual college athlete prop bets. The following wagers may not be available depending on your particular state laws.

College Football Prop Bets
+ Displays more odds
BetMGM Sports Betting BetMGM
Bet
Louisville
USC
First Team To Score
12/27/23 8:00pm EST
-145+110Bet
Louisville
USC
No Touchdown
To Score 1st Touchdown
12/27/23 8:00pm EST
-160+110+10000Bet
Louisville
USC
Game to Overtime
12/27/23 8:00pm EST
Yes +900No -5000Bet
Louisville
USC
Both Teams Score 10+
12/27/23 8:00pm EST
Yes -2500No +950Bet
BetMGM Sports Betting BetMGM
Louisville
USC
Both Teams Score 20+
12/27/23 8:00pm EST
Yes -225No +175Bet
Louisville
USC
Both Teams Score 30+
12/27/23 8:00pm EST
Yes +270No -375Bet

Recent Meetings Since 2019

Recent Meetings Since 2019
WeekGameResultMargin
2023
Bowls
Louisville vs USC
Wednesday, December 27th, 2023
Directv Holiday Bowl
USC 42, LOU 28
Petco Park
USC by 14

Team Standings

2023-2024 College Football Regular Season Standings - Louisville, USC
Team Conf Conf% W L PF PA Home Away Strk
ACC
#19 Louisville7-10.8751044302986-12-1L3
Pac-12
USC5-40.556855444474-33-2W1

Louisville & USC Futures Odds

Latest NCAA Championship odds, if available, for each team. Review odds for other teams and learn the best College Football bets.

Louisville Championship Odds
2024-25 Louisville NCAA College Football Championship Odds

Team
BetMGM Sports Betting BetMGM
Louisville
+25000
Bet
USC Championship Odds
2024-25 USC NCAA College Football Championship Odds

Team
BetMGM Sports Betting BetMGM
USC
+5000
Bet

Team Schedules & Results


2023-24 Louisville Games & Results
WeekMatchupDate & Result
Week 1Louisville vs
Georgia Tech
LOU 39, GT 34
Friday, September 1st, 2023
Week 2Murray State vs
Louisville
LOU 56, MUR 0
Thursday, September 7th, 2023
Week 3Louisville vs
Indiana
LOU 21, IU 14
Saturday, September 16th, 2023
Week 4Boston College vs
Louisville
LOU 56, BC 28
Saturday, September 23rd, 2023
Week 5Louisville vs
NC State
LOU 13, NCSU 10
Friday, September 29th, 2023
Week 6Notre Dame vs
Louisville
LOU 33, ND 20
Saturday, October 7th, 2023
Week 7Louisville vs
Pittsburgh
PITT 38, LOU 21
Saturday, October 14th, 2023
Week 9Duke vs
Louisville
LOU 23, DUKE 0
Saturday, October 28th, 2023
Week 10Virginia Tech vs
Louisville
LOU 34, VT 3
Saturday, November 4th, 2023
Week 11Virginia vs
Louisville
LOU 31, UVA 24
Thursday, November 9th, 2023
Week 12Louisville vs
Miami (FL)
LOU 38, MIA 31
Saturday, November 18th, 2023
Week 13Kentucky vs
Louisville
UK 38, LOU 31
Saturday, November 25th, 2023
Week 14Louisville vs
Florida State
FSU 16, LOU 6
Saturday, December 2nd, 2023
BowlsLouisville vs
USC
Directv Holiday Bowl
USC 42, LOU 28
Wednesday, December 27th, 2023


2023-24 USC Games & Results
WeekMatchupDate & Result
Week 1San Jose State vs
USC
USC 56, SJSU 28
Saturday, August 26th, 2023
Week 1Nevada vs
USC
USC 66, NEV 14
Saturday, September 2nd, 2023
Week 2Stanford vs
USC
USC 56, STAN 10
Saturday, September 9th, 2023
Week 4USC vs
Arizona State
USC 42, ASU 28
Saturday, September 23rd, 2023
Week 5USC vs
Colorado
USC 48, COLO 41
Saturday, September 30th, 2023
Week 6Arizona vs
USC
USC 43, ARIZ 41 (3OT)
Saturday, October 7th, 2023
Week 7USC vs
Notre Dame
ND 48, USC 20
Saturday, October 14th, 2023
Week 8Utah vs
USC
UTAH 34, USC 32
Saturday, October 21st, 2023
Week 9USC vs
California
USC 50, CAL 49
Saturday, October 28th, 2023
Week 10Washington vs
USC
WASH 52, USC 42
Saturday, November 4th, 2023
Week 11USC vs
Oregon
ORE 36, USC 27
Saturday, November 11th, 2023
Week 12UCLA vs
USC
UCLA 38, USC 20
Saturday, November 18th, 2023
BowlsLouisville vs
USC
Directv Holiday Bowl
USC 42, LOU 28
Wednesday, December 27th, 2023

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Louisville vs USC College Football Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Wednesday, December 27th, 2023 at 8:00 pm EST, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's College Football page, look for the Louisville vs USC Game.

    Navigate to the sportsbook's College Football page. Next, look for live or upcoming matchups. Select the Louisville vs USC Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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