The Wildcats will play the Trojans on Friday, November 7th, 2025. The matchup takes place at Los Angeles Memorial Coliseum. Watch this exciting Week 11 matchup at 9:00 pm EST. Check local listings for coverage on FOX.
Learn more about College Football betting with our handy tutorial and guide. We explain spread, total and money line bets.
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Table of Contents
- Matchup Stats
- Paddy O'Parlay
- Best Odds
- Interactive Odds Example
- Prop Bets
- Recent Meetings
- Team Standings
- Futures Odds
- Team Pages
- Team Schedules & Results
- Other Games Today
Key Matchup Stats
It's now the back half of the 2025 college football season, as we begin looking towards the annual bowl games and college football playoffs. Week 11 action features a matchup between Northwestern and USC, kicking off at Los Angeles Memorial Coliseum on Friday, November 7th, 2025. Have a look at the following season performance stats to better handicap this game.
- SportsBetting3.com Power Rankings - Northwestern has a 93.00 conference power ranking for the 2025 season. The conference power ranking for USC is 96.00.
- Away Northwestern - As Week 11 looms, Northwestern currently has a 1-2 record as an away team for the 2025 regular season. This ranks them 3rd in the Big Ten Conference for away team wins. Remember that a team's overall record and schedule strength will affect whether or not they make a bowl game or the playoffs.
- Home USC - USC has a 4-0 record as a home team as they approach Week 11. They currently rank 3rd in the Big Ten Conference for home team wins. Continue monitoring their performance to see if they have a shot at a postseason bowl game or playoff berth.
- Points Scored - For the 2025 season, Northwestern ranks 16th (180) in the Big Ten Conference, with USC currently ranking 3rd (318) for points scored in the Big Ten Conference.
- Points Against - Northwestern stands 14th (134) in the Big Ten Conference for points scored by opponents in the 2025 college football season. USC sits at 8th (179) in the Big Ten Conference for points against them heading into Week 11 of the 2025 season.
- Team Records - Northwestern has a 5-3 overall record for the 2025 regular season, with USC currently 6-2 for the 2025 college football regular season.
Paddy O'Parlay
The "Sports Network" talking heads have nothing on my Irish arse!
Get ready for a wild showdown between Northwestern and USC on November 7th!
The game will be held at Los Angeles Memorial Coliseum in the heart of Hollywood.
Northwestern sits at 93.00 in the Power Rankings, while USC is at 96.00.
Northwestern has a 5-3 record, while USC boasts a 6-2 standing.
Place a bet on this college football game at BetMGM or BetRivers, see this matchup's prop bets below, and compare each sportsbook's point spread, total, and moneyline.
Best Wildcats at Trojans Odds
| Underdog Northwestern | Favorite USC |
|---|---|
| Over | Under |
|---|---|
| Underdog Northwestern | Favorite USC |
|---|---|
Matchup Odds FAQs
USC is a -14 -118 point spread favorite at BetMGM, while Northwestern is a +14 -110 point spread underdog at BetMGM.
The best over line is 53.5 -115 points at BetMGM, which means you risk $115 to win $100 betting the over. The best under line is 53.5 -105 points at BetMGM, and that means you risk $105 to win $100 betting the under.
USC is a -625 moneyline favorite at BetMGM and Northwestern is a +450 moneyline underdog at BetMGM.
College Football Odds Example
|
Game |
 BetMGMBet |
|---|---|
Northwestern
USC
11/07/25 9:00pm EST | +14 -110-14 -118 |
Underdog Northwestern - Northwestern bettors risk $100 to win $90.91 at -110 odds.
A +14 Northwestern underdog bet wins if they lose by 13 or fewer, tie, or win outright. The bet pushes if they lose by 14. Your bet loses if they lose by 15 or more.
Favorite USC - USC bettors risk $100 to win $84.75 at -118 odds.
A -14 USC favorite bet wins if they win by 15 or more. The bet pushes if they win by 14. Your bet loses if they win by 13 or fewer, tie, or lose outright.
Northwestern at USC Prop Bets
Important Note: Some states expressly forbid individual college athlete prop bets. The following wagers may not be available depending on your particular state laws.
| BetMGM Bet |
|
|---|---|
Northwestern
USC
No Touchdown
To Score 1st Touchdown
11/07/25 9:00pm EST | +210-325+10000Bet |
Northwestern
USC
Game to Overtime
11/07/25 9:00pm EST | Yes +1400No -10000Bet |
Northwestern
USC
Both Teams Score 10+
11/07/25 9:00pm EST | Yes -650No +425Bet |
Northwestern
USC
Both Teams Score 20+
11/07/25 9:00pm EST | Yes +100No -130Bet |
| BetMGM | |
Northwestern
USC
Both Teams Score 30+
11/07/25 9:00pm EST | Yes +550No -1000Bet |
Recent Meetings Since 2021
| Week | Game | Result | Margin |
|---|---|---|---|
| 2025 Week 11 | Northwestern vs USC Friday, November 7th, 2025 | USC 38, NU 17 Los Angeles Memorial Coliseum | USC by 21 |
Team Standings
| Team | Conf | Conf% | W | L | PF | PA | Home | Away | Strk |
|---|---|---|---|---|---|---|---|---|---|
| #16 USC | 7-2 | 0.778 | 9 | 3 | 438 | 269 | 7-0 | 2-3 | W1 |
| Northwestern | 4-5 | 0.444 | 6 | 6 | 270 | 251 | 5-2 | 1-4 | L1 |
Northwestern & USC Futures Odds
Latest NCAA Championship odds, if available, for each team. Review odds for other teams and learn the best College Football bets.
Northwestern Championship OddsNo NCAA College Football Championship TM Northwestern YR: futures available
USC Championship OddsNo NCAA College Football Championship TM USC YR: futures available
Northwestern & USC Team Pages
Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:
Team Schedules & Results
| Week | Matchup | Date & Result |
|---|---|---|
| Week 1 | Northwestern vs Tulane | TULN 23, NU 3 Saturday, August 30th, 2025 |
| Week 2 | Western Illinois vs Northwestern | NU 42, WIU 7 Friday, September 5th, 2025 |
| Week 3 | Oregon vs Northwestern | ORE 34, NU 14 Saturday, September 13th, 2025 |
| Week 5 | UCLA vs Northwestern | NU 17, UCLA 14 Saturday, September 27th, 2025 |
| Week 6 | Louisiana-Monroe vs Northwestern | NU 42, ULM 7 Saturday, October 4th, 2025 |
| Week 7 | Northwestern vs Penn State | NU 22, PSU 21 Saturday, October 11th, 2025 |
| Week 8 | Purdue vs Northwestern | NU 19, PUR 0 Saturday, October 18th, 2025 |
| Week 9 | Northwestern vs Nebraska | NEB 28, NU 21 Saturday, October 25th, 2025 |
| Week 11 | Northwestern vs USC | USC 38, NU 17 Friday, November 7th, 2025 |
| Week 12 | Michigan vs Northwestern | MICH 24, NU 22 Saturday, November 15th, 2025 |
| Week 13 | Minnesota vs Northwestern | NU 38, MINN 35 Saturday, November 22nd, 2025 |
| Week 14 | Northwestern vs Illinois | ILL 20, NU 13 Saturday, November 29th, 2025 |
| Bowls | Central Michigan vs Northwestern Gameabove Sports Bowl | Friday, December 26th, 2025 1:00 pm EST |
| Week | Matchup | Date & Result |
|---|---|---|
| Week 1 | Missouri State vs USC | USC 73, MOST 13 Saturday, August 30th, 2025 |
| Week 2 | Georgia Southern vs USC | USC 59, GASO 20 Saturday, September 6th, 2025 |
| Week 3 | USC vs Purdue | USC 33, PUR 17 Saturday, September 13th, 2025 |
| Week 4 | Michigan State vs USC | USC 45, MSU 31 Saturday, September 20th, 2025 |
| Week 5 | USC vs Illinois | ILL 34, USC 32 Saturday, September 27th, 2025 |
| Week 7 | Michigan vs USC | USC 31, MICH 13 Saturday, October 11th, 2025 |
| Week 8 | USC vs Notre Dame | ND 34, USC 24 Saturday, October 18th, 2025 |
| Week 10 | USC vs Nebraska | USC 21, NEB 17 Saturday, November 1st, 2025 |
| Week 11 | Northwestern vs USC | USC 38, NU 17 Friday, November 7th, 2025 |
| Week 12 | Iowa vs USC | USC 26, IOWA 21 Saturday, November 15th, 2025 |
| Week 13 | USC vs Oregon | ORE 42, USC 27 Saturday, November 22nd, 2025 |
| Week 14 | UCLA vs USC | USC 29, UCLA 10 Saturday, November 29th, 2025 |
| Bowls | USC vs TCU Valero Alamo Bowl | Tuesday, December 30th, 2025 9:00 pm EST |
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the Northwestern vs USC College Football Game
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Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Friday, November 7th, 2025 at 9:00 pm EST, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
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Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
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Tap to the sportsbook's College Football page, look for the Northwestern vs USC Game.
Navigate to the sportsbook's College Football page. Next, look for live or upcoming matchups. Select the Northwestern vs USC Game.
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Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.