Notre Dame vs USC Football Odds

The Fighting Irish will play the Trojans on Saturday, November 26th, 2022. The matchup takes place at Los Angeles Memorial Coliseum. Watch this exciting Week 13 matchup at 7:30 pm EST. Check local listings for coverage on ABC.

Learn more about College Football betting with our handy tutorial and guide. We explain spread, total and money line bets. Read the following to understand point spread betting.

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Point Spread
Underdog

Notre Dame
Favorite

USC
SportsBetting3.com has analyzed the latest lines. Review our "Point Spread" table above to smash the books. BetRivers VA has the best favorite USC point spread at -4.5 points. BetRivers has the best underdog Notre Dame point spread at +4.5 points. Review our point spread betting tutorial and video for more information.

Total
OverUnder
The over under line estimates the combined total of each team's final score. BetRivers has the best over line of 63.5 points laying $108 to win $100. BetMGM has the best under line of 63.5 points.

Moneyline
Underdog

Notre Dame
Favorite

USC
Here are money lines for the outright winner. Favorite USC has a minus value. Lay $180 to win $100 at BetRivers. Underdog Notre Dame has a positive value. Risk $100 at BetMGM to win $165.

SportsBetting3.com College Football Odds Example

College Football Odds and Outcomes Explained

Game
BetRivers BetRivers
Bet
Notre Dame
USC
11/26/22 7:30pm EST

Underdog Notre Dame - Notre Dame bettors risk $100 to win $90.91 at -110 odds.

A +4.5 Notre Dame underdog bet wins if they lose by 4 or fewer, tie, or win outright. Your bet loses if they lose by 5 or more.

Favorite USC - USC bettors risk $100 to win $90.91 at -110 odds.

A -4.5 USC favorite bet wins if they win by 5 or more. Your bet loses if they win by 4 or fewer, tie, or lose outright.

Notre Dame at USC Prop Bets

College Football Prop Bets
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Notre Dame
USC
11/26/22 7:30pm EST - First Team To Score
Notre Dame
USC
Tie
11/26/22 7:30pm EST - First to 20 Points

Recent Meetings Since 2018

WeekGameResultMargin
2022
Week 13
Notre Dame vs USC
Saturday, November 26th, 2022
USC 38, ND 27
Los Angeles Memorial Coliseum
USC by 11
2021
Week 8
USC vs Notre Dame
Saturday, October 23rd, 2021
ND 31, USC 16
Notre Dame Stadium
Notre Dame by 15
2019
Week 7
USC vs Notre Dame
Saturday, October 12th, 2019
ND 30, USC 27
Notre Dame Stadium
Notre Dame by 3
2018
Week 13
Notre Dame vs USC
Saturday, November 24th, 2018
ND 24, USC 17
Los Angeles Memorial Coliseum
Notre Dame by 7

Team Season Win Totals

The following are each team's season win totals. Learn more about season win totals.

Notre Dame Season Win Total
2022 College Football Notre Dame Season Win Total
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Notre Dame
2022 Season Win Total
USC Season Win Total
2022 College Football USC Season Win Total
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USC
2022 Season Win Total

College Football Championship Odds

Latest NCAA Championship odds, if available, for each team. Review odds for other teams and learn the best College Football bets here.

Notre Dame Championship Odds

No NCAA College Football Championship TM Notre Dame YR: futures available

USC Championship Odds
2023 USC NCAA College Football Championship Odds

Team
BetRivers BetRivers BetMGM BetMGM
USC

2022 Notre Dame Games & Results

WeekMatchupDate & Time
Week 1Notre Dame vs
Ohio State
OSU 21, ND 10
Saturday, September 3rd, 2022
Week 2Marshall vs
Notre Dame
MRSH 26, ND 21
Saturday, September 10th, 2022
Week 3California vs
Notre Dame
ND 24, CAL 17
Saturday, September 17th, 2022
Week 4Notre Dame vs
North Carolina
ND 45, UNC 32
Saturday, September 24th, 2022
Week 6BYU vs
Notre Dame
ND 28, BYU 20
Saturday, October 8th, 2022
Week 7Stanford vs
Notre Dame
STAN 16, ND 14
Saturday, October 15th, 2022
Week 8UNLV vs
Notre Dame
ND 44, UNLV 21
Saturday, October 22nd, 2022
Week 9Notre Dame vs
Syracuse
ND 41, SYR 24
Saturday, October 29th, 2022
Week 10Clemson vs
Notre Dame
ND 35, CLEM 14
Saturday, November 5th, 2022
Week 11Notre Dame vs
Navy
ND 35, NAVY 32
Saturday, November 12th, 2022
Week 12Boston College vs
Notre Dame
ND 44, BC 0
Saturday, November 19th, 2022
Week 13Notre Dame vs
USC
USC 38, ND 27
Saturday, November 26th, 2022

2022 USC Games & Results

WeekMatchupDate & Time
Week 1Rice vs
USC
USC 66, RICE 14
Saturday, September 3rd, 2022
Week 2USC vs
Stanford
USC 41, STAN 28
Saturday, September 10th, 2022
Week 3Fresno State vs
USC
USC 45, FRES 17
Saturday, September 17th, 2022
Week 4USC vs
Oregon State
USC 17, ORST 14
Saturday, September 24th, 2022
Week 5Arizona State vs
USC
USC 42, ASU 25
Saturday, October 1st, 2022
Week 6Washington State vs
USC
USC 30, WSU 14
Saturday, October 8th, 2022
Week 7USC vs
Utah
UTAH 43, USC 42
Saturday, October 15th, 2022
Week 9USC vs
Arizona
USC 45, ARIZ 37
Saturday, October 29th, 2022
Week 10California vs
USC
USC 41, CAL 35
Saturday, November 5th, 2022
Week 11Colorado vs
USC
USC 55, COLO 17
Friday, November 11th, 2022
Week 12USC vs
UCLA
USC 48, UCLA 45
Saturday, November 19th, 2022
Week 13Notre Dame vs
USC
USC 38, ND 27
Saturday, November 26th, 2022
Week 14Utah vs
USC
Friday, December 2nd, 2022
8:00 pm EST

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