Ohio vs Buffalo Football Odds

The Bobcats will play the Bulls on Friday, November 28th, 2025. The matchup takes place at UB Stadium. Watch this exciting Week 14 matchup at 12:00 pm EST. Check local listings for coverage on ESPNU.

Learn more about College Football betting with our handy tutorial and guide. We explain spread, total and money line bets.


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Table of Contents

Key Matchup Stats

We're now in the home stretch of the 2025 college football season, with Ohio and Buffalo meeting at UB Stadium for a key late-season matchup on Friday, November 28th, 2025. The playoffs are fast approaching, along with the annual Bowl games that kick off in December. Here's an overview of some important 2025 performance data for each team.

  • SportsBetting3.com Power Rankings - As we wrap up the 2025 regular season, Ohio has notched a 99.00 MAC Conference conference power ranking. On the other side of the gridiron, Buffalo has a 96.33 MAC Conference power ranking.
  • Away Ohio - Looking at Week 14, Ohio heads into this matchup with a 1-4 record as an away team. This ranks them 3rd in the MAC Conference for away team wins in 2025. Remember that a team's overall record and schedule strength will affect whether or not they make a December bowl game or qualify for the playoffs.
  • Home Buffalo - Meanwhile, Buffalo has a 2-4 record as a home team for 2025. They currently rank 5th in the MAC Conference for home team wins. Let's see if they can add another win to their record when they battle Ohio on Friday, November 28th, 2025.
  • Points Scored - Now late in the 2025 season, Ohio ranks 2nd (313) in the MAC Conference, with Buffalo currently ranking 6th (262) for points scored in the MAC Conference.
  • Points Against - Ohio currently stands 9th (249) in the MAC Conference for points scored by opponents in the 2025 college football season. Their opponent, Buffalo, ranks 8th (251) in the MAC Conference for points against them as the 2025 college football season comes to a close.
  • Team Records - As we head into Week 14, Ohio has a 7-4 overall record for the 2025 regular season, with Buffalo possessing a 5-6 standing for the 2025 college football season.

Paddy O'Parlay

The "Sports Network" talking heads have nothing on my Irish arse!

Paddy O'Parlay
Paddy O'Parlay

Top o' the morning to ya, lads and lasses! Ohio is ready to rumble in Buffalo.

The showdown will go down at UB Stadium in a crucial Week 14 matchup.

The regular season is winding down, with December bowl games on the horizon.

Ohio holds a Power Ranking of 99.00, while Buffalo comes in at 96.33.

The Bobcats stand at 7-4, while the Bulls are currently at 5-6.

We recommend BetRivers or BetMGM for a bet on this game. Review this game's prop bets.

Compare the best point spread, total, and moneylines from our partner sportsbooks below.

Best Bobcats at Bulls Odds


Best Point Spread Betting Odds
Underdog

Buffalo
Favorite

Ohio
Ohio has a -7 -110 point spread at BetMGM OH. They are the point spread favorite in this matchup. Buffalo has a +7 -110 point spread at BetMGM OH. Buffalo is the point spread underdog. Review how to bet on a point spread with our text and video tutorials.

Best Total Betting Odds
OverUnder
BetMGM has the best over line of 44.5 points. Risk $115 to win $100. BetMGM has the best under line of 44.5 points. Risk $105 to win $100. Our tutorial explains more about total bets.

Best Moneyline Betting Odds
Underdog

Buffalo
Favorite

Ohio
Ohio is the -250 moneyline favorite. Risk $250 to win $100 on Ohio at BetMGM. Buffalo is the +200 underdog at BetMGM. Risk $100 to win $200 on Buffalo. Learn more about how to bet on money lines.

Matchup Odds FAQs

What is the point spread for the Ohio vs Buffalo College Football game on Friday, November 28th, 2025?

Ohio is a -7 -110 point spread favorite at BetMGM, while Buffalo is a +7 -110 point spread underdog at BetMGM.

What is the over-under total line for the Ohio vs Buffalo College Football game on Friday, November 28th, 2025?

The best over line is 44.5 -115 points at BetMGM, which means you risk $115 to win $100 betting the over. The best under line is 44.5 -105 points at BetMGM, and that means you risk $105 to win $100 betting the under.

What is the moneyline for the Ohio vs Buffalo College Football game on Friday, November 28th, 2025?

Ohio is a -250 moneyline favorite at BetMGM and Buffalo is a +200 moneyline underdog at BetMGM.

College Football Odds Example

College Football Odds and Outcomes Explained

Game
BetMGM Sports Betting BetMGM
Bet
Ohio
Buffalo
11/28/25 12:00pm EST
-7 -110+7 -110
Bet $100 at BetMGM Ohio
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Underdog Buffalo - Buffalo bettors risk $100 to win $90.91 at -110 odds.

A +7 Buffalo underdog bet wins if they lose by 6 or fewer, tie, or win outright. The bet pushes if they lose by 7. Your bet loses if they lose by 8 or more.

Favorite Ohio - Ohio bettors risk $100 to win $90.91 at -110 odds.

A -7 Ohio favorite bet wins if they win by 8 or more. The bet pushes if they win by 7. Your bet loses if they win by 6 or fewer, tie, or lose outright.

Ohio at Buffalo Prop Bets

Important Note: Some states expressly forbid individual college athlete prop bets. The following wagers may not be available depending on your particular state laws.

College Football Prop Bets
+ Displays more odds
BetMGM Sports Betting BetMGM
Bet
Ohio
Buffalo
No Touchdown
To Score 1st Touchdown
11/28/25 12:00pm EST
-190+130+10000Bet
Ohio
Buffalo
Game to Overtime
11/28/25 12:00pm EST
Yes +1200No -10000Bet
Ohio
Buffalo
Both Teams Score 10+
11/28/25 12:00pm EST
Yes -525No +350Bet
Ohio
Buffalo
Both Teams Score 20+
11/28/25 12:00pm EST
Yes +154No -200Bet
BetMGM Sports Betting BetMGM
Ohio
Buffalo
Both Teams Score 30+
11/28/25 12:00pm EST
Yes +1000No -3000Bet

Recent Meetings Since 2021

Recent Meetings Since 2021
WeekGameResultMargin
2025
Week 14
Ohio vs Buffalo
Friday, November 28th, 2025
OHIO 31, BUFF 26
UB Stadium
Ohio by 5
2024
Week 9
Buffalo vs Ohio
Saturday, October 26th, 2024
OHIO 47, BUFF 16
Peden Stadium
Ohio by 31
2023
Week 11
Ohio vs Buffalo
Tuesday, November 7th, 2023
OHIO 20, BUFF 10
UB Stadium
Ohio by 10
2022
Week 10
Buffalo vs Ohio
Tuesday, November 1st, 2022
OHIO 45, BUFF 24
Peden Stadium
Ohio by 21
2021
Week 7
Ohio vs Buffalo
Saturday, October 16th, 2021
BUFF 27, OHIO 26
UB Stadium
Buffalo by 1

Team Standings

2025-2026 College Football Regular Season Standings - Ohio, Buffalo
Team Conf Conf% W L PF PA Home Away Strk
Ohio6-20.750843442756-02-4W2
Buffalo4-40.500572882822-53-2L3

Ohio & Buffalo Futures Odds

Latest NCAA Championship odds, if available, for each team. Review odds for other teams and learn the best College Football bets.

Ohio Championship Odds

No NCAA College Football Championship TM Ohio YR: futures available

Buffalo Championship Odds

No NCAA College Football Championship TM Buffalo YR: futures available

Ohio & Buffalo Team Pages

Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Schedules & Results


2025-26 Ohio Games & Results
WeekMatchupDate & Result
Week 1Ohio vs
Rutgers
RUTG 34, OHIO 31
Thursday, August 28th, 2025
Week 2West Virginia vs
Ohio
OHIO 17, WVU 10
Saturday, September 6th, 2025
Week 3Ohio vs
Ohio State
OSU 37, OHIO 9
Saturday, September 13th, 2025
Week 4Gardner-Webb vs
Ohio
OHIO 52, GWEB 35
Saturday, September 20th, 2025
Week 5Bowling Green vs
Ohio
OHIO 35, BGSU 20
Saturday, September 27th, 2025
Week 6Ohio vs
Ball State
BALL 20, OHIO 14
Saturday, October 4th, 2025
Week 8Northern Illinois vs
Ohio
OHIO 48, NIU 21
Saturday, October 18th, 2025
Week 9Ohio vs
Eastern Michigan
OHIO 28, EMU 21
Saturday, October 25th, 2025
Week 11Miami (OH) vs
Ohio
OHIO 24, M-OH 20
Tuesday, November 4th, 2025
Week 12Ohio vs
Western Michigan
WMU 17, OHIO 13
Tuesday, November 11th, 2025
Week 13UMass vs
Ohio
OHIO 42, MASS 14
Tuesday, November 18th, 2025
Week 14Ohio vs
Buffalo
OHIO 31, BUFF 26
Friday, November 28th, 2025
BowlsUNLV vs
Ohio
Scooter's Coffee Frisco Bowl
Tuesday, December 23rd, 2025
9:00 pm EST


2025-26 Buffalo Games & Results
WeekMatchupDate & Result
Week 1Buffalo vs
Minnesota
MINN 23, BUFF 10
Thursday, August 28th, 2025
Week 2St. Francis (PA) vs
Buffalo
BUFF 45, SFPA 6
Saturday, September 6th, 2025
Week 3Buffalo vs
Kent State
BUFF 31, KENT 28
Saturday, September 13th, 2025
Week 4Troy vs
Buffalo
TROY 21, BUFF 17
Saturday, September 20th, 2025
Week 5UConn vs
Buffalo
CONN 20, BUFF 17
Saturday, September 27th, 2025
Week 6Eastern Michigan vs
Buffalo
BUFF 31, EMU 30 (OT)
Saturday, October 4th, 2025
Week 8Buffalo vs
UMass
BUFF 28, MASS 21
Saturday, October 18th, 2025
Week 9Akron vs
Buffalo
AKR 24, BUFF 16
Saturday, October 25th, 2025
Week 10Buffalo vs
Bowling Green
BUFF 28, BGSU 3
Saturday, November 1st, 2025
Week 12Buffalo vs
Central Michigan
CMU 38, BUFF 19
Wednesday, November 12th, 2025
Week 13Miami (OH) vs
Buffalo
M-OH 37, BUFF 20
Wednesday, November 19th, 2025
Week 14Ohio vs
Buffalo
OHIO 31, BUFF 26
Friday, November 28th, 2025

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Ohio vs Buffalo College Football Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Friday, November 28th, 2025 at 12:00 pm EST, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's College Football page, look for the Ohio vs Buffalo Game.

    Navigate to the sportsbook's College Football page. Next, look for live or upcoming matchups. Select the Ohio vs Buffalo Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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