The Mustangs will play the Cardinals on Saturday, September 19th, 2026. The matchup takes place at L&N Federal Credit Union Stadium. Watch this exciting Week 3 matchup at 3:30 pm EDT. Check local listings for coverage on ESPN2.
Learn more about College Football betting with our handy tutorial and guide. We explain spread, total and money line bets.
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Table of Contents
- Matchup Stats
- Best Odds
- Interactive Odds Example
- Prop Bets
- Recent Meetings
- Team Standings
- Futures Odds
- Team Pages
- Team Schedules & Results
- Other Games Today
Key Matchup Stats
The 2026 college football season continues with SMU matching up against Louisville at L&N Federal Credit Union Stadium. Let's review how each team is doing so far to better understand how this game will play out.
- SportsBetting3.com Power Rankings - SMU has a 98.33 conference power ranking for the 2026 season so far. The 2026 conference power ranking for Louisville is 97.00.
- Away SMU - SMU currently has a 1-0 record as an away team for the 2026 regular season, ranking them 1st in the ACC Conference for away team wins. Not much can be concluded from this stat just yet, so stay tuned.
- Home Louisville - So far, Louisville has a 1-0 record as a home team. They currently rank 2nd in the ACC Conference for home team wins in 2026. Keep tabs on this figure, as it will change in the coming weeks.
- Points Scored - SMU ranks 6th (83) in the ACC Conference, with Louisville currently ranking 3rd (97) for points scored in the 2026 ACC Conference.
- Points Against - SMU stands 9th (34) in the ACC Conference for points scored by opponents in 2026. Louisville sits at 6th (54) in the 2026 ACC Conference for points against in the 2026 season.
- Team Records - SMU has a 2-0 regular season overall record, with Louisville currently possessing a 1-1 regular season standing for the 2026 NCAAF season.
Best Mustangs at Cardinals Odds
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College Football Odds Example
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SMU at Louisville Prop Bets
Important Note: Some states expressly forbid individual college athlete prop bets. The following wagers may not be available depending on your particular state laws.
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SMU
Louisville
9/19/26 3:30pm EDT | Pending |
Recent Meetings Since 2022
| Week | Game | Result | Margin |
|---|---|---|---|
| 2026 Week 3 | SMU vs Louisville Saturday, September 19th, 2026 | LOU 41, SMU 31 L&N Federal Credit Union Stadium | Louisville by 10 |
| 2025 Week 13 | Louisville vs SMU Saturday, November 22nd, 2025 | SMU 38, LOU 6 Gerald J. Ford Stadium | SMU by 32 |
| 2024 Week 6 | SMU vs Louisville Saturday, October 5th, 2024 | SMU 34, LOU 27 L&N Federal Credit Union Stadium | SMU by 7 |
Team Standings
| Team | Conf | Conf% | W | L | PF | PA | Home | Away | Strk |
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| #16 Louisville | 1-0 | 1.000 | 2 | 1 | 138 | 85 | 2-0 | 0-0 | W2 |
| #22 SMU | 1-1 | 0.500 | 2 | 1 | 114 | 75 | 1-0 | 1-1 | L1 |
SMU & Louisville Futures Odds
Latest NCAA Championship odds, if available, for each team. Review odds for other teams and learn the best College Football bets.
SMU Championship OddsNo NCAA College Football Championship TM SMU YR: futures available
Louisville Championship OddsNo NCAA College Football Championship TM Louisville YR: futures available
SMU & Louisville Team Pages
Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:
Team Schedules & Results
| Week | Matchup | Date & Result |
|---|---|---|
| Week 1 | SMU vs Florida State | SMU 27, FSU 24 Monday, September 7th, 2026 |
| Week 2 | UC Davis vs SMU | SMU 56, UCD 10 Saturday, September 12th, 2026 |
| Week 3 | SMU vs Louisville | LOU 41, SMU 31 Saturday, September 19th, 2026 |
| Week 4 | Missouri State vs SMU | Saturday, September 26th, 2026 9:00 pm EDT |
| Week 5 | Boston College vs SMU | Saturday, October 3rd, 2026 12:00 pm EDT |
| Week 7 | Virginia vs SMU | Saturday, October 17th, 2026 12:00 am EDT |
| Week 8 | California vs SMU | Saturday, October 24th, 2026 12:00 am EDT |
| Week 9 | SMU vs Syracuse | Saturday, October 31st, 2026 12:00 am EDT |
| Week 10 | Virginia Tech vs SMU | Friday, November 6th, 2026 7:00 pm EST |
| Week 11 | Wake Forest vs SMU | Saturday, November 14th, 2026 12:00 am EST |
| Week 12 | SMU vs Notre Dame | Saturday, November 21st, 2026 7:30 pm EST |
| Week 13 | SMU vs Stanford | Saturday, November 28th, 2026 12:00 am EST |
| Week | Matchup | Date & Result |
|---|---|---|
| Week 1 | Louisville vs Ole Miss | MISS 41, LOU 38 Sunday, September 6th, 2026 |
| Week 2 | Villanova vs Louisville | LOU 59, VILL 13 Friday, September 11th, 2026 |
| Week 3 | SMU vs Louisville | LOU 41, SMU 31 Saturday, September 19th, 2026 |
| Week 4 | Wake Forest vs Louisville | Saturday, September 26th, 2026 12:00 pm EDT |
| Week 5 | Louisville vs NC State | Saturday, October 3rd, 2026 3:30 pm EDT |
| Week 6 | Florida State vs Louisville | Friday, October 9th, 2026 7:00 pm EDT |
| Week 7 | Louisville vs Syracuse | Saturday, October 17th, 2026 12:00 am EDT |
| Week 9 | Stanford vs Louisville | Saturday, October 31st, 2026 12:00 am EDT |
| Week 10 | Louisville vs Georgia Tech | Saturday, November 7th, 2026 12:00 am EST |
| Week 11 | Louisville vs North Carolina | Saturday, November 14th, 2026 12:00 am EST |
| Week 12 | Pittsburgh vs Louisville | Saturday, November 21st, 2026 12:00 am EST |
| Week 13 | Louisville vs Kentucky | Saturday, November 28th, 2026 12:00 am EST |
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the SMU vs Louisville College Football Game
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Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Saturday, September 19th, 2026 at 3:30 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
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Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
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Tap to the sportsbook's College Football page, look for the SMU vs Louisville Game.
Navigate to the sportsbook's College Football page. Next, look for live or upcoming matchups. Select the SMU vs Louisville Game.
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Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.
Other September 19, 2026 NCAAFB Games
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- Buffalo vs Penn State - 9/19/26 12:00pm EDT
- North Texas vs Texas State - 9/19/26 12:00pm EDT
- Akron vs Minnesota - 9/19/26 12:00pm EDT
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- Lafayette vs Columbia - 9/19/26 12:00pm EDT
- Kent State vs Ohio State - 9/19/26 12:00pm EDT
- Villanova vs Long Island University - 9/19/26 12:00pm EDT
- Dartmouth vs Lehigh - 9/19/26 12:00pm EDT
- Bowling Green vs Iowa State - 9/19/26 12:00pm EDT
- Georgia vs Arkansas - 9/19/26 12:00pm EDT
- West Georgia vs East Tennessee State - 9/19/26 12:00pm EDT
- Mercer vs Georgia Tech - 9/19/26 12:00pm EDT
- North Carolina vs Clemson - 9/19/26 12:00pm EDT
- Arizona State vs Kansas - 9/19/26 12:00pm EDT
- Eastern Michigan vs Wisconsin - 9/19/26 12:30pm EDT
- NC State vs Vanderbilt - 9/19/26 12:45pm EDT
- VMI vs Davidson - 9/19/26 1:00pm EDT
- Harvard vs New Hampshire - 9/19/26 1:00pm EDT
- Cornell vs Colgate - 9/19/26 1:00pm EDT
- Princeton vs Bryant - 9/19/26 1:00pm EDT
- Valparaiso vs Indiana State - 9/19/26 1:00pm EDT
- Wyoming vs Central Michigan - 9/19/26 1:00pm EDT
- Southern Illinois vs Illinois - 9/19/26 2:00pm EDT
- Maine vs Boston College - 9/19/26 2:00pm EDT
- Yale vs Holy Cross - 9/19/26 2:00pm EDT
- Southern Utah vs St. Thomas - 9/19/26 2:00pm EDT
- Rhode Island vs Stony Brook - 9/19/26 2:30pm EDT
- Presbyterian vs Western Carolina - 9/19/26 2:30pm EDT
- Temple vs Toledo - 9/19/26 3:00pm EDT
- Eastern Illinois vs Illinois State - 9/19/26 3:00pm EDT
- Penn vs Bucknell - 9/19/26 3:00pm EDT
- Central Connecticut vs Montana State - 9/19/26 3:00pm EDT
- UTEP vs Michigan - 9/19/26 3:30pm EDT
- Miami (OH) vs Cincinnati - 9/19/26 3:30pm EDT
- Monmouth vs Albany - 9/19/26 3:30pm EDT
- Utah State vs Utah - 9/19/26 3:30pm EDT
- USC vs Rutgers - 9/19/26 3:30pm EDT
- Duquesne vs Washington State - 9/19/26 3:30pm EDT
- Stonehill vs UMass - 9/19/26 3:30pm EDT
- Kentucky vs Texas A&M - 9/19/26 3:30pm EDT
- Georgetown vs Richmond - 9/19/26 3:30pm EDT
- Northern Iowa vs Iowa - 9/19/26 4:00pm EDT
- Stanford vs Duke - 9/19/26 4:00pm EDT
- Louisiana Tech vs Baylor - 9/19/26 4:00pm EDT
- Ball State vs Liberty - 9/19/26 4:00pm EDT
- Hampton vs Norfolk State - 9/19/26 4:00pm EDT
- Abilene Christian vs Idaho - 9/19/26 4:00pm EDT
- Western Kentucky vs Indiana - 9/19/26 4:00pm EDT
- Mississippi State vs South Carolina - 9/19/26 4:15pm EDT
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- Florida State vs Alabama - 9/19/26 5:10pm EDT
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- Western Michigan vs Rice - 9/19/26 7:00pm EDT
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- UConn vs Southern Miss - 9/19/26 7:00pm EDT
- Morehead State vs Western Illinois - 9/19/26 7:00pm EDT
- Troy vs Missouri - 9/19/26 7:00pm EDT
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- Youngstown State vs South Dakota State - 9/19/26 7:00pm EDT
- Florida vs Auburn - 9/19/26 7:00pm EDT
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- Nicholls vs Sam Houston State - 9/19/26 7:00pm EDT
- Delaware State vs South Florida - 9/19/26 7:00pm EDT
- Murray State vs Oklahoma State - 9/19/26 7:00pm EDT
- UT-Martin vs Memphis - 9/19/26 7:00pm EDT
- Eastern Washington vs Washington - 9/19/26 7:15pm EDT
- North Dakota vs Nebraska - 9/19/26 7:15pm EDT
- West Virginia vs Virginia - 9/19/26 7:30pm EDT
- Michigan State vs Notre Dame - 9/19/26 7:30pm EDT
- Virginia Tech vs Maryland - 9/19/26 7:30pm EDT
- LSU vs Ole Miss - 9/19/26 7:30pm EDT
- New Mexico vs Oklahoma - 9/19/26 7:30pm EDT
- Colorado vs Northwestern - 9/19/26 7:30pm EDT
- Kennesaw State vs Tennessee - 9/19/26 7:45pm EDT
- San Diego vs Cal Poly - 9/19/26 8:00pm EDT
- Stephen F. Austin vs Prairie View A&M - 9/19/26 8:00pm EDT
- Northern Arizona vs Utah Tech - 9/19/26 8:00pm EDT
- UAB vs Louisiana - 9/19/26 8:02pm EDT
- Northwestern State vs Weber State - 9/19/26 8:02pm EDT
- UTSA vs Texas - 9/19/26 8:02pm EDT
- Arkansas State vs TCU - 9/19/26 8:05pm EDT
- BYU vs Colorado State - 9/19/26 8:10pm EDT
- Charlotte vs Appalachian State - 9/19/26 9:00pm EDT
- Stetson vs UC Davis - 9/19/26 10:00pm EDT
- South Dakota vs Boise State - 9/19/26 10:00pm EDT
- James Madison vs San Diego State - 9/19/26 10:00pm EDT
- Northern Illinois vs Arizona - 9/19/26 10:30pm EDT
- North Dakota State vs Sacramento State - 9/19/26 10:30pm EDT
- Fresno State vs San Jose State - 9/19/26 11:00pm EDT
- Montana vs Oregon State - 9/19/26 11:00pm EDT
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