Wake Forest vs Clemson Football Odds

The Demon Deacons will play the Tigers on Saturday, November 20th, 2021. The matchup takes place at Memorial Stadium (Clemson, SC). Watch this exciting Week 12 matchup at 12:00 pm EST. Check local listings for coverage on ESPN.

Learn more about College Football betting with our handy tutorial and guide. We explain spread, total and money line bets. Read the following to understand point spread betting.

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2:37pm EDT
TBD VA
VA Odds Pending
No VA Point Spread lines available for this game.

Wake Forest at Clemson Prop Bets

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Wake Forest
Clemson
11/20/21 12:00pm EST
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Recent Meetings Since 2017

WeekGameResultMargin
2022
Week 4
Clemson vs Wake Forest
Saturday, September 24th, 2022
CLEM 51, WAKE 45 (2OT)
Truist Field
Clemson by 6
2021
Week 12
Wake Forest vs Clemson
Saturday, November 20th, 2021
CLEM 48, WAKE 27
Memorial Stadium (Clemson, SC)
Clemson by 21
2020
Week 2
Clemson vs Wake Forest
Saturday, September 12th, 2020
CLEM 37, WAKE 13
Truist Field
Clemson by 24
2019
Week 12
Wake Forest vs Clemson
Saturday, November 16th, 2019
CLEM 52, WAKE 3
Memorial Stadium (Clemson, SC)
Clemson by 49
2018
Week 6
Clemson vs Wake Forest
Saturday, October 6th, 2018
CLEM 63, WAKE 3
Truist Field
Clemson by 60
2017
Week 6
Wake Forest vs Clemson
Saturday, October 7th, 2017
CLEM 28, WAKE 14
Memorial Stadium (Clemson, SC)
Clemson by 14

Team Season Win Totals

The following are each team's season win totals. Learn more about season win totals.

Wake Forest Season Win Total
2022 College Football Wake Forest Season Win Total
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2022 Season Win Total
Clemson Season Win Total
2022 College Football Clemson Season Win Total
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Clemson
2022 Season Win Total

College Football Championship Odds

Latest NCAA Championship odds, if available, for each team. Review odds for other teams and learn the best College Football bets here.

Wake Forest Championship Odds
2023 Wake Forest NCAA College Football Championship Odds

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Clemson Championship Odds
2023 Clemson NCAA College Football Championship Odds

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2021 Wake Forest Games & Results

WeekMatchupDate & Time
Week 1Old Dominion vs
Wake Forest
WAKE 42, ODU 10
Friday, September 3rd, 2021
Week 2Norfolk State vs
Wake Forest
WAKE 41, NORF 16
Saturday, September 11th, 2021
Week 3Florida State vs
Wake Forest
WAKE 35, FSU 14
Saturday, September 18th, 2021
Week 4Wake Forest vs
Virginia
WAKE 37, UVA 17
Friday, September 24th, 2021
Week 5Louisville vs
Wake Forest
WAKE 37, LOU 34
Saturday, October 2nd, 2021
Week 6Wake Forest vs
Syracuse
WAKE 40, SYR 37 (OT)
Saturday, October 9th, 2021
Week 8Wake Forest vs
Army
WAKE 70, ARMY 56
Saturday, October 23rd, 2021
Week 9Duke vs
Wake Forest
WAKE 45, DUKE 7
Saturday, October 30th, 2021
Week 10Wake Forest vs
North Carolina
UNC 58, WAKE 55
Saturday, November 6th, 2021
Week 11NC State vs
Wake Forest
WAKE 45, NCST 42
Saturday, November 13th, 2021
Week 12Wake Forest vs
Clemson
CLEM 48, WAKE 27
Saturday, November 20th, 2021
Week 13Wake Forest vs
Boston College
WAKE 41, BC 10
Saturday, November 27th, 2021
Week 14Pittsburgh vs
Wake Forest
PITT 45, WAKE 21
Saturday, December 4th, 2021
BowlsWake Forest vs
Rutgers
Taxslayer Gator Bowl
WAKE 38, RUTG 10
Friday, December 31st, 2021

2021 Clemson Games & Results

WeekMatchupDate & Time
Week 1Georgia vs
Clemson
UGA 10, CLEM 3
Saturday, September 4th, 2021
Week 2South Carolina State vs
Clemson
CLEM 49, SCST 3
Saturday, September 11th, 2021
Week 3Georgia Tech vs
Clemson
CLEM 14, GT 8
Saturday, September 18th, 2021
Week 4Clemson vs
NC State
NCST 27, CLEM 21 (2OT)
Saturday, September 25th, 2021
Week 5Boston College vs
Clemson
CLEM 19, BC 13
Saturday, October 2nd, 2021
Week 7Clemson vs
Syracuse
CLEM 17, SYR 14
Friday, October 15th, 2021
Week 8Clemson vs
Pittsburgh
PITT 27, CLEM 17
Saturday, October 23rd, 2021
Week 9Florida State vs
Clemson
CLEM 30, FSU 20
Saturday, October 30th, 2021
Week 10Clemson vs
Louisville
CLEM 30, LOU 24
Saturday, November 6th, 2021
Week 11UConn vs
Clemson
CLEM 44, CONN 7
Saturday, November 13th, 2021
Week 12Wake Forest vs
Clemson
CLEM 48, WAKE 27
Saturday, November 20th, 2021
Week 13Clemson vs
South Carolina
CLEM 30, SC 0
Saturday, November 27th, 2021
BowlsClemson vs
Iowa State
Cheez-It Bowl
CLEM 20, ISU 13
Wednesday, December 29th, 2021

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